摘要
阴茎海绵体纤维化是导致难治性勃起功能障碍的重要原因,其确切发病机制尚未完全阐明,常规治疗效果不佳,严重影响男性的生活质量和身心健康。随着研究的深入,二维剪切波弹性成像(2D-SWE)、分子影像等技术的进展对海绵体纤维化的早期诊断、分级及分期提供了可能。干细胞治疗、能量治疗、靶向治疗及中医药治疗等的研究在抗阴茎海绵体纤维化中展现了良好的应用前景。该文主要综述阴茎海绵体纤维化诊断及治疗方式的研究进展。
Penis cavernosa fibrosis is an important cause of refractory erectile dysfunction.Its exact pathogenesis remains incompletely elucidated,and conventional treatment is not effective,seriously affecting the quality of life,physical and mental health of men.With the deepening of research,the progress of two-dimensional shear wave elastography(2D-SWE)and molecular imaging provides the possibility for the early diagnosis,grading and staging of cavernous fibrosis.Studies on stem cell therapy,energy-based treatments,targeted therapy,and traditional Chinese medicine show promising applications in the anti-penile cavernous fibrosis.This article reviews the research progress in the diagnosis and treatment of penile cavernosis fibrosis.
作者
张琪(综述)
徐润楠(综述)
吕伯东(审校)
黄文杰(审校)
ZHANG Qi;XU Run-nan;LÜ Bo-dong;HUANG Wen-jie(The Second School of Clinical Medicine,Zhejiang University of Chinese Medicine,Hangzhou 310053,China;Department of Urology,The Second Affiliated Hospital Zhejiang University School of medicine,Hangzhou 310009,China;Zhejiang Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for the Prevention and Treatment of Sexual Dysfunction,Hangzhou 310000,China)
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2023年第4期358-363,共6页
National Journal of Andrology
基金
国家自然科学基金面上项目(82174376、82074433)
浙江省中医药防治重大疾病攻关计划(2018ZY007)
