摘要
对140例糖尿病患者进行血液流变学测定,观察了眼球结膜血细胞的聚集性,并与82例非糖尿病患者作比较。结果表明:糖尿病患者全血粘度升高,血细胞聚集性也升高;而伴有视网膜病变者全血粘度和血细胞聚集性则进一步升高,眼球结膜血细胞的聚集性和血液液粘度密切相关(r=+0.6983,P<0.01)。由此提示:糖尿病患者有明显的血流障碍,是发生视刚膜病变的病理生理学基础。
Seven hemorheological tests,namely,hematecrit,whole blood relative viscosity,whote blood reduced viscosity,plasma relative viscosity,ESR,erythrocyte sedimentation equation coefficient K and erythrocyte electrophoretic time,were studied in 140 diabetics,with 82 non-diabetics as controls.At the same time,the aggregation of blood cells in bulbar conjunctiva was observed.It was found that whole blood viscosity was significantly higher in diabetics.This was related to the increased aggregation of blood ceils and plasma viscosity and decreased blood cell plasticity.The further increase of whole blood viscosity in diabetics with fundoscopic retinopathy aggravated the disturbance of blood flow.The aggregation of blood cells in bulbar conjunctiva correlated well with the whole blood viscosity(r=+0.6983,P<0.01).This confirms the disturbance of blood flow in diabetics and it might be the physiopathologic basis of development of diabetic retinopathy.
出处
《上海医学》
CAS
1983年第2期85-89,共5页
Shanghai Medical Journal