摘要
目的探讨自制丹香乳癖散外敷联合天宗穴刮痧在治疗肝郁痰凝型乳癖患者中的临床效果及对患者证候积分、毒副反应的影响。方法选择2018年3月—2019年3月嘉兴中医院治疗的84例肝郁痰凝型乳癖患者,采用随机数字表法分为对照组和观察组,各42例。对照组给予自制丹香乳癖散外敷治疗,观察组在对照组基础上联合天宗穴刮痧治疗,10 d治疗后对患者效果进行评估,从肿块硬度、肿块范围、肿块大小及全身伴随症状对2组治疗前、治疗后10 d证候积分进行评定;采用全自动生化分析仪完成患者卵泡期雌二醇及孕酮水平测定;比较2组证候积分、激素水平及毒副反应。结果观察组治疗后10 d肿块硬度(1.42±0.28)分、肿块范围(1.41±0.27)分、肿块大小(1.32±0.24)分及全身伴随症状评分(1.51±0.27)分,均低于对照组(t=13.249、13.009、13.296、12.797,均P<0.05);观察组治疗后10 d卵泡期雌二醇水平[(121.39±10.23)pg/mL]低于对照组的(132.57±12.15)pg/mL(t=4.562,P<0.05);孕酮水平[(14.64±1.48)ng/mL]高于对照组的(12.12±1.36)ng/mL(t=8.125,P<0.001);2组治疗后胃肠道反应、血压波动、肝肾功能异常等不良反应发生率差异均无统计学意义(P>0.05)。结论将自制丹香乳癖散外敷联合天宗穴刮痧用于肝郁痰凝型乳癖中降低患者证候积分,改善激素水平,并未增加毒副反应发生率,值得推广应用。
Objective To investigate the clinical effect of self-made Danxiang Rupi Powder and Tianzhu Point Scraping in patients with liver stagnation and phlegm-type chyle and its influence on syndrome score and toxic side effects.Methods Eighty-four patients with liver stagnation and chyle-type chyle who were treated from March 2018 to March 2019 were enrolled.The random number table was divided into control group(n=42)and observation group(n=42).The control group was treated with self-made Danxiang granules and external application.The observation group was treated with Tianzong acupoint scraping on the basis of the control group.The effect of the patient was evaluated after 10 days of treatment.From the mass of the tumor,the extent of the tumor,the size of the tumor and the symptoms of the whole body.The scores of syndromes before and 10 days after treatment were evaluated.The levels of estradiol and progesterone in the follicular phase were determined by automatic biochemical analyzer.The syndrome scores,hormone levels and side effects were compared between the two groups.Results In the observation group,the mass of the mass(1.42±0.28),the extent of the tumor(1.41±0.27),the size of the mass(1.32±0.24)and the score of the systemic accompanying symptom(1.51±0.27)were lower than those of the control group.(t=13.249,13.009,13.296,12.797,all P<0.05).Estradiol level[(121.39±10.23)pg/mL]in the follicular phase of the observation group was lower than that of the control group(t=4.562,P<0.05).Progesterone level[(14.64±1.48)ng/mL]was higher than that of the control group(t=8.125,P<0.05).Gastrointestinal reaction,blood pressure fluctuation,liver and kidney dysfunction,dizziness headache and other occurrences in the observation group and the control group after treatment were not statistically significant(P>0.05).Conclusion The self-made Danxiang sputum powder external application combined with Tianzong point scraping for liver stagnation and phlegm-type chyle reduces the syndrome score of patients,improves hormone levels,an
作者
邱娟娟
许月萍
于恩光
邢亚华
QIU Juan-juan;XU Yue-ping;YU En-guang;XING Ya-hua(Department of Breast Surgery,Jiaxing Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Traditional Chinese Medicine,Jiaxing,Zhejiang 314001,China)
出处
《中华全科医学》
2020年第1期122-124,共3页
Chinese Journal of General Practice
基金
2019年度浙江省中医药科学研究基金(2019ZA123).
关键词
丹香乳癖散外敷
天宗穴刮痧
肝郁痰凝型乳癖
证候积分
激素水平
毒副反应
Danxiang sputum sputum external application
Tianzong point scraping
Liver stagnation phlegm chyle
Syndrome score
Hormone levels
Toxic side effects
