摘要
目的观察PICCO指导脓毒症并发心力衰竭患者液体复苏的疗效。方法收集本院2019年6月至2021年5月收治的60例脓毒症并发心力衰竭患者,用随机数字法分组,其中30例接受常规方式液体复苏(对照组),另30例在PICCO指导下进行液体复苏(观察组),比较两组治疗效果。结果对照组与治疗组在接受治疗之前各项指标差异无统计学意义。经过治疗后,观察组GEF、GEDI、ITBL、MAP高于对照组,ELWI、NT-proBNP低于对照组(P<0.05)。观察组EGDT达标率(83.33%vs 56.67%)、7d死亡率(3.33%vs 20%)、28d死亡率(6.67%vs33.33%)显著低于对照组。此外,观察者住ICU时间明显比对照组短,差异具有统计学意义(P<0.05)。结论脓毒症并发心力衰竭患者在接受液体复苏治疗时,加以PICCO指导,确保治疗的精准性,可显著改善其血流动力学指标和心功能,降低死亡率。
Objective To observe the effect of PICCO on fluid resuscitation in patients with sepsis complicated with heart failure.Methods 60 patients with sepsis complicated with heart failure treated in our hospital from June 2019 to may 2021 were collected and divided into two groups randomly.Among them,30 patients received conventional fluid resuscitation(control group)and the other 30 patients underwent fluid resuscitation under the guidance of PICCO(observation group).The therapeutic effects of the two groups were compared.Results There was no significant difference between the control group and the treatment group before treatment.After treatment,GEF,GEDI,ITBL and MAP in the observation group were higher than those in the control group,ELWI and NT proBNP were lower than those in the control group(P<0.05).The compliance rate of EGDT in the observation group was(83.33%vs 56.67%),the 7-day mortality rate(3.33%vs 20%),and the 28 day mortality rate(6.67%vs 33.33%)was significantly lower than that of the control group.In addition,the length of stay in ICU was significantly shorter than that in the control group(P<0.05).Conclusions PICCO guidance can significantly improve the hemodynamic indexes and cardiac function,decrease the mortality in patients with sepsis complicated with heart failure.
作者
李明
胡俞
曹莉
何胜
张辉
LiMing;Hu Yu;Cao Li;He Sheng;Zhang Hui(Department of critical medicine,Shiyan people's Hospital,Shenzhen,Guangdong.)
基金
深圳市宝安区科技计划项目(项目编号:20200506105157108)
