摘要
目的分析和描述上海市新生儿低出生体重(low birth weight,LBW)发生率的产妇年龄、产婴时期和产妇出生队列效应及其特点。方法收集覆盖全市所有接产机构报告的2015—2021年单胎新生儿出生登记信息;基于年龄-时期-队列模型,应用STATA的apc_ie模块分别估计产妇年龄、产婴时期和产妇出生队列对上海市单胎新生儿LBW发生率的影响效应。结果该地产妇的年龄效应表现为25~31岁组RR值均低于1(相应P均<0.05),38~42岁组RR值均>1(除40~41岁组外,相应P<0.05);非本地产妇24~32岁组RR值均低于1(相应P均<0.05),37~42岁组RR值均>1(相应P均<0.05);年龄别RR随年龄增加而增大。两类产妇人群的产婴时期效应表现为2015—2017年的RR值均低于1(相应P均<0.05),2020—2021年RR值均>1(相应P均<0.05);时期别RR呈逐年上升。两类产妇人群出生队列效应表现为大部分队列别RR的P均>0.05。2015年以来两类产妇人群高龄比例呈上升趋势,其变化特征与时期别RR相似。结论逐年上升的高龄产妇比例是上海市新生儿LBW发生率上升的重要原因,有关部门应不断完善生育相关福利政策,以降低高龄生育比例。
Objective To analyze and describe maternal age-period-cohort effects on the incidence rate of neonatal low body weight(LBW)and the features of the effects in Shanghai Municipality.Methods We collected the birth medical records of singleton newborns from all delivery service institutions in Shanghai Municipality from 2015 to 2021.Based on the age-period-cohort model,apc_ie module in STATA was used to estimate maternal age-period-cohort effects on the incidence rate of LBW in singleton newborns in Shanghai Municipality.Results As for Shanghai ID(SID)mothers,the effect of maternal age on the incidence rate of neonatal LBW displayed that the values of relative risks(RRs)in the age groups of 25-31 years old were all lower than 1(all relative P<0.05),and those in the age groups of 38-42 years old were all bigger than 1(all relative P<0.05 except those in the age groups of 40-41 years old).As for non-SID mothers,the effect of maternal age on the incidence rate of neonatal LBW revealed that the values of RRs in the age groups of 24-32 years were all lower than 1(all relative P<0.05),and those in the age groups of 37-42 years old were all bigger than 1(all relative P<0.05).Maternal age-specific RRs increased with the increasing age.As for both SID and non-SID mothers,the effect of birth period on the incidence rate of neonatal LBW exhibited that the values of RRs in 2015-2017 were all lower than 1(all relative P<0.05),and those in 2020-2021 were both bigger than 1(all relative P<0.05).Maternal period-specific RRs presented an upward trend.As for both SID and non-SID mothers,the effect of maternal cohort on the incidence rate of neonatal LBW showed that most of the cohort RRs had P values bigger than 0.05.The proportion of pregnancy at very advanced maternal age in both SID and non-SID mothers demonstrated an ascending trend since 2015,and its changing features were similar to those of period-specific RRs.Conclusion The year-by-year increase in the proportion of pregnancy at very advanced maternal age is an important facto
作者
周峰
虞慧婷
范和玉
王春芳
ZHOU Feng;YU Huiting;FAN Heyu;WANG Chunfang(Shanghai Municipal Center for Disease Control and Prevention,Shanghai 200336,China;School of Environmental and Biological Science,Rutgers University,New Brunswick,NJ 08901-8525,USA)
出处
《实用预防医学》
CAS
2023年第10期1223-1227,共5页
Practical Preventive Medicine
