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生物人工硬脑膜在颅脑损伤患者去骨瓣减压术中的应用

Application of Bioartificial Dura Mater in Decompressive Craniectomy in Patients with Craniocerebral Injury
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摘要 目的观察生物人工硬脑膜在颅脑损伤患者去骨瓣减压术中的应用效果。方法回顾性分析2013年2月-2017年2月我院80例颅脑损伤患者临床资料,所有患者均采用在去骨瓣减压术中用生物人工硬脑膜减张缝合修补硬脑膜治疗,记录患者手术相关指标、治疗前后认知功能评分(MMSE)、生活自理能力评分(BI)、预后评分(GOS),随访患者术后并发症发生率。结果患者平均手术时间为(75.29±8.34)min,平均术中出血量为(70.38±12.14)m L,硬膜外总引流量为(54.29±8.34)m L,患者ICU住院天数为(8.19±2.24)d;患者MMSE评分、BI评分、GOS评分术后3个月均提高,手术前后比较差异有统计学意义(P<0.05);随访患者术后并发症发生率,显示有1例出现脑积水,1例皮下积液,1例切口感染,占3.75%(3/80)。结论生物人工硬脑膜在颅脑损伤患者去骨瓣减压术中的应用,能够减轻手术创伤,促进患者认知功能及自理能力提升,并发症少,有利于增强患者预后,可在临床广泛推广。 Objective This paper aims to observe the application effect of bioartificial dura mater in decompressive craniectomy in patients with craniocerebral injury.Methods 80 patients with craniocerebral injury were treated with bio artificial dural decompressive craniectomy.The operation related indexes,cognitive function score(MMSE),self-care ability score(BI)and prognosis score(GOS)were recorded before and after treatment.The incidence of postoperative complications was followed up.Results The average operation time was(75.29±8.34)min,the average intraoperative blood loss was(70.38±12.14)m L,the total epidural drainage volume was(54.29±8.34)m L,the length of stay in ICU was(8.19±2.24)d;the MMSE score,Bi score and GOS score were increased 3 months after operation,and the difference was statistically significant(P<0.05);the incidence of postoperative complications was statistically significant(P<0.05)There were 1 case of hydrocephalus,1 case of subcutaneous effusion and 1 case of incision infection.Conclusion The application of bioartificial dura mater in decompressive craniectomy in patients with craniocerebral injury can reduce the surgical trauma,promote the cognitive function and self-care ability of patients,with fewer complications,which is conducive to enhance the prognosis of patients.
作者 钟鸣
出处 《透析与人工器官》 2017年第3期19-20,23,共3页 Chinese Journal of Dialysis and Artificial Organs
关键词 生物人工硬脑膜 颅脑损伤 去骨瓣减压术 MMSE评分 GOS评分 并发症 bioartificial dura mater craniocerebral injury decompressive craniectomy MMSE score GOS score complications
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