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人工肝血液净化治疗肝功能衰竭患者的临床效果

Clinical Effect of Artificial Liver Blood Purification in the Treatment of Patients with Liver Failure
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摘要 目的探讨人工肝血液净化疗法在肝功能衰竭治疗中的临床有效性。方法选取2015年6月-2020年6月在本院进行肝功能治疗的患者96例,随机分为观察组和对照组,对观察组患者进行人工肝血液净化治疗,对治疗后的有效率、患者的肝功能指标进行记录。结果观察组和对照组的总有效率分别为66.67%和27.45%,观察组与对照组治疗有效率存在统计学差异(P<0.05);两组患者的天门冬氨酸氨基转移酶(AST)、碱性磷酸酶(ALP)、直接胆红素、血清总胆红素、γ-谷氨酰转移酶指标均存在统计学差异(P<0.05),且观察组治疗效果显著优于对照组。结论肝功能衰竭在采用常规内科治疗的基础上,采用人工肝血液净化会提高治疗的有效性,值得临床推广应用。 Objective:To investigate the clinical effect of artificial liver blood purification in the treatment of patients with liver failure.Methods:A total of 96 patients with liver function admitted to our hospital from June 2015 to June 2020 were selected,and were randomly divided into observation group and control group.The observation group was treated with artificial liver blood purification.The effective rate after treatment and liver function indexes of patients were recorded.Results:The total effective rates of the observation group and the control group were 66.67%and 27.45%,respectively,and the effective rates of the observation group and the control group were statistically different(P<0.05).There were statistically significant differences in aspartate aminotransferas(AST),alkaline phosphatase(ALP),direct bilirubin,serum total bilirubin,andγ-glutamyltransferase between the two groups(P<0.05),and the therapeutic effect of the observation group was significantly better than that of the control group.Conclusion:On the basis of conventional medical treatment,artificial liver blood purification can improve the effectiveness of treatment for liver failure,which is worthy promoting in clinic.
作者 黄慧 HUANG Hui(Fifth People's Hospital,Ganzhou Jiangxi 341000,China)
出处 《透析与人工器官》 2023年第2期68-71,共4页 Chinese Journal of Dialysis and Artificial Organs
关键词 人工肝 血液净化 肝功能衰竭 临床效果 artificial liver blood purification liver failure clinical effect
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