摘要
目的了解驻马店市2016-2018年丙型肝炎(简称丙肝)病毒(HCV)检测和报告情况,为促进当地丙肝病例的检测发现提供参考。方法收集驻马店市部分医院2016-2018年实验室的血液丙肝病毒抗体(抗-HCV)和HCV核糖核酸(RNA)检测信息,分析血液抗-HCV检测率和阳性率、HCV RNA检测率和阳性率;收集所调查医院报告的HCV RNA阳性病例信息,与医院实验室检测出的血液HCV RNA阳性病例进行比较,分析HCV RNA阳性病例报告率。结果 2016-2018年,6家医院就诊者中抗-HCV平均检测率为5.6%。三级医院检测出的血液抗-HCV阳性率平均为2.3%,HCV RNA检测率平均为54.9%,HCV RNA阳性检出率为81.7%,HCV RNA阳性报告率为52.2%。二级医院检测出的抗-HCV阳性率平均为5.2%,HCV RNA检测率平均为50.5%,HCV RNA阳性检出率为79.9%,HCV RNA阳性报告率为16.9%;三级医院(χ^2趋势=5.93,P <0.01)与二级医院(χ^2趋势=8.02,P <0.01)HCV RNA检测率三年间均呈上升趋势。结论驻马店市医疗机构HCV RNA阳性病例报告率整体仍较低,特别是二级医院。医疗机构需强化丙肝报告能力提高报告数量和质量,为卫生行政部门制定丙肝防治政策提供准确信息。
Objective To understand the status of hepatitis C detection and reporting during 2016-2018 in Zhumadian, so as to provide references for promotion of hepatitis C case detection. Methods The blood anti-HCV and HCV RNA detection information were collected from hospitals in Zhumadian during 2016-2018, and the positive rate of anti-HCV, detection rate and positive rate of HCV-RNA were analyzed accordingly. The report rate of HCV RNA positive cases was analyzed by comparing the basic data of HCV RNA positive cases reported by the investigated hospitals with the HCV RNA positive cases detected by the hospital laboratory. Results The average detection rate of anti-HCV among patients was 5.6%. The positive rate of anti-HCV, the detection rate of HCV RNA, the positive rate of HCV RNA and the report rate of HCV RNA positive cases in tertiary hospitals were 2.3%, 54.9%, 81.7%, and 52.2% respectively during 2016-2018. The positive rate of anti-HCV, the detection rate of HCV RNA, the positive rate of HCV RNA and the report rate of HCV RNA positive cases in secondary hospitals were 5.2%, 50.5%, 79.9% and 16.9% respectively. The detection rates in tertiary(χ^2=5.93,P < 0.001) and secondary hospitals(χ^2=8.02,P < 0.001) were rising. Conclusion Although the detection rate of HCV RNA in Zhumadian hospitals is on the rise, the overall report rate of HCV RNA positive cases is still low, especially in the secondary hospitals. Hospitals need to strengthen the reporting capacity of HCV and improve the quantity and quality of the report, so as to provide accurate information for health administration departments to formulate policies on HCV prevention and treatment.
作者
王耀
毛宇嵘
孙定勇
韩娟
庞琳
李宁
杨文杰
李洁
龚涛
郭敬业
冯小飞
WANG Yao;MAO Yurong;SUN Dingyong;HAN Juan;PANG Lin;LI Ning;YANG Wenjie;LI Jie;GONG Tao;GUO Jingye;FENG Xiaofei(National Center for AIDS/STD Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Institute for STD/AIDS Prevention and Control,Henan Provincial Center for Disease Control and Prevention,Zhengzhou 450016,Henan;Zhumadian Center for Disease Control and Prevention,Zhumadian 463000,Henan)
出处
《中国艾滋病性病》
CAS
CSCD
北大核心
2020年第2期198-200,共3页
Chinese Journal of Aids & STD
基金
广西八桂学者艾滋病防控关键技术岗位专项.
关键词
丙型病毒性肝炎
检出率
报告率
hepatitis C
detection rate of anti-HCV
report rate
