摘要
目的分析在冲击治疗小儿急性病毒性心肌炎中丙种球蛋白的临床效果。方法据随机的原则将于2017年3月至2018年8月该院接受治疗的76例小儿急性病毒性心肌炎患儿均分为两组,即常规组(38例)和丙种组(38例)。将常规的治疗方法如抗病毒药物、维生素C、肾上腺皮质激素等应用于常规组患儿进行治疗,而丙种组则在常规组患儿对症治疗的前提下加用丙种球蛋白进行治疗,将两组患儿治疗后的肌酸激酶(CK)、肌酸激酶同工酶MB (CK-MB)、乳酸脱氢酶(LDH)的心肌酶谱情况变化以及治疗效果进行比对。结果治疗后丙种组患儿的CK、CK-MB、LDH的下降水平均显著低于常规组,P<0.05;丙种组的总有效率(89.47%)大于常规组的总有效率(68.42%),P<0.05,差异具有统计学意义。结论冲击治疗小儿急性病毒性心肌炎在对症治疗的前提下,应用丙种球蛋白治疗的临床疗效较为显著,对患儿的心肌酶谱改善情况较为明显,值得临床应用。
【Objective】To analyze the clinical effect of gamma globulin in the treatment of acute viral myocarditis in children with impulse therapy.【Methods】According to the principle of randomization, 76 children with acute viral myocarditis treated in our hospital from March 2017 to August 2018 were divided into two groups: routine group(38 cases) and C group(38 cases).Conventional treatment methods such as antiviral drugs, vitamin C and adrenocortical hormones were used to treat children in the conventional group, while gamma globulin was added to treat children in group C on the premise of symptomatic treatment. The myocardial enzymes of creatine kinase(CK), creatine kinase isoenzyme MB(CK-MB) and lactate dehydrogenase(LDH) were changed after treatment in the two groups. Chemicals and therapeutic effects were compared. 【Results】 After treatment, the average precipitation of CK, CK-MB and LDH in group C was significantly lower than that in the conventional group(P<0.05);the total effective rate in group C(89.47%) was higher than that in the conventional group(68.42%) and the difference was statistically significant(P<0.05).【Conclusion】On the premise of symptomatic treatment of acute viral myocarditis in children, the clinical effect of gamma globulin therapy is remarkable, and the improvement of myocardial enzymes in children is obvious, which is worthy of clinical application.
作者
徐宣启
XU Xuanqi(Emergency Department,Children's Hospital Affiliated to Zhengzhou University(Henan Provincial Children's Hospital,Zhengzhou Children's Hospital),Zhengzhou,Henan 450000,China)
出处
《中国医学工程》
2020年第1期37-39,共3页
China Medical Engineering
