摘要
目的:调查研究TTM治疗糖尿病的药用植物,探索其降糖机理及治疗糖尿病并发症的机制。方法:以"糖尿病""民间医学""泰国药用植物""传统医学"为关键词,在数据库中进行文献检索,获取治疗糖尿病药用植物的科学验证信息。结果:共纳入药用植物143种,其中104种药用植物的化学成分和降糖机制通过实验验证,筛选24种药用植物,从中分离46种具有降糖作用的活性化合物,其降糖机制已通过实验证实。结论:通过对TTM治疗糖尿病的药用植物调查研究,为进一步探索药用植物的作用机制,发掘民族医药提供新思路。
Objective:To investigate and study the medicinal plants for treating diabetes in traditional medicine in Thailand,explore the hypoglycemic mechanism and the mechanism of treating diabetic complications.Methods:Ethnopharmacological information on the plant materials used in TTM for diabetes treatment was collected through literature search in a range of scientific databases using the search terms:diabetes,folk medicine,Thailand medicinal plants,traditional medicine.Information regarding scientific evidence on the antidiabetic effects of surveyed species was obtained.Results:143 species used for diabetes management in TTM were reviewed,with 104 of them have experimental evidences to support claims regarding the mechanisms and phytochemicals underlying their antidiabetic properties.Moreover,46 bioactive displaying effective antidiabetic effects have been isolated from 24 species,their underlying mechanisms of action being fully or partially disclosed.Conclusion:The review will spark further research on Thailand plants for the development of new standardized phytomedicines through drug discovery programs.
作者
Catarina Andradea
Nelson G.M.Gomesa
Sutsawat Duangsrisai
Catarina Andradea;Nelson G.M.Gomesa;Sutsawat Duangsrisai(Pharmacognosy Laboratory,Department of Chemistry,Faculty of Agriculture,University of Porto,Porto,Portugal;Department of Botany,Faculty of Science,Kasetsart University,Bangkok,Thailand)
出处
《亚太传统医药》
2021年第8期1-5,共5页
Asia-Pacific Traditional Medicine
关键词
泰国传统医学
民族药理学
萜烯
降糖药
多酚
生物碱
Thailand Traditional Medicine
Ethnopharmacology
Terpenes
Antidiabetic
Polyphenols
Alkaloids
