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多指标正交试验法优选红参水提工艺研究 被引量:6

Optimization of Water Extraction Process for Red Ginseng by Multi-index Orthogonal Test
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摘要 目的:优选红参的水提工艺。方法:采用正交试验法,以人参皂苷Rg1、Rb1、Re含量和干膏得率的综合评分为评价指标,以浸泡时间、提取次数、提取时间和加水量4个因素设计L9(34)正交试验,优选红参的最佳水提工艺,并进行验证。结果:红参最佳水提工艺为加8倍量水,浸泡30min,提取3次,每次0.5h。验证试验的干膏得率均值为56.47%、人参皂苷Rg1的含量均值为0.1977%、人参皂苷Re的含量均值为0.1045%、人参皂苷Rb1的含量均值为0.2025%,各指标的RSD均小于3%。结论:优选的水提工艺稳定可行,可为红参的相关制剂研究提供依据。 Objective:To optimize the water extraction technology of Red ginseng.Methods:Taking the comprehensive score of the content of ginsenoside Rg;,Rb;and Re and the dry extract yield as evaluation indexes.Taking soaking time,extraction times,extraction time and water addition as influence factors,L;(3;)orthogonal test was designed to optimize the optimal extraction process of red ginseng,and a verification test was performed.Results:The optimal water extraction process of Red ginseng was soaked in 8 times of water for 30 min and extracted for 3 times,0.5 heach time.The average dry extract yield,ginsenoside Rg;content,ginsenoside Rb;content and ginsenoside Re content of the verification experiment were 56.47%,0.1977%,0.1045%and 0.2025%respectively,and the RSDof each index was less than 3%.Conclusion:The optimized water extraction process is stable and feasible,which can provide the basis for further preparation development of Red ginseng.
作者 陈丹燕 余欣彤 彭帮贵 王瑜婷 汪梅 陈江平 魏梅 Chen Danyan;Yu Xintong;Peng Banggui;Wang Yuting;Wang Mei;Chen Jiangping;Wei Mei(Guangdong YiFang Pharmaceutical Co.,Ltd.,Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granule,Foshan 528244,China)
出处 《亚太传统医药》 2021年第10期42-45,共4页 Asia-Pacific Traditional Medicine
基金 广东省科技计划(2018B030323004)
关键词 红参 正交试验 综合评分 干膏得率 人参皂苷 水提工艺 Red Ginseng Orthogonal Test Comprehensive Score The Dry Extract Yield Ginsenoside Water Extraction Process
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