摘要
镁合金材料作为可生物降解植入材料因其可在体内逐渐降解、吸收、消耗和排泄,手术区域愈合后无需二次手术取出。该材料有良好的生物降解性和生物相容性,有与骨骼相似的机械性能,使其在临床上被广泛研究。然而,镁合金在生物体内易腐蚀,限制了其作为骨植入材料的应用。本文从镁合金的腐蚀机理出发,对近年来通过镁合金骨植入材料表面改性从而控制材料的降解速率和改善生物相容性的研究作一综述。
As a biodegradable implant material,magnesium alloy material can be degraded,absorbed,consumed or excreted in the body.It does not require a secondary surgery after the surgical area is healed.The material has good biodegradability and biocompatibility,and has similar mechanical properties to bones.It is widely studied in the clinic.However,magnesium alloys are prone to corrosion in living organisms,limiting their use as bone implant materials.Based on the corrosion mechanism of magnesium alloys,this article reviewed the recent studies on the surface modification of magnesium alloy bone implant materials to control the degradation rate of materials and improve their biocompatibility.
作者
秦浩添
翁鉴
于斐
张卫飞
李国庆
张晟
齐天天
曾晖
QIN Haotian;WENG Jian;YU Fei;ZHANG Weifei;LI Guoqing;ZHANG Sheng;QI Tiantian;ZENG Hui(National&Local Joint Engineering Research Center of Orthopaedic Biomaterials,Peking University Shenzhen Hospital,Shenzhen 518036;Department of Bone&Joint Surgery,Peking University Shenzhen Hospital,Shenzhen 518036,Guangdong,China)
出处
《中华骨与关节外科杂志》
2021年第4期315-320,共6页
Chinese Journal of Bone and Joint Surgery
基金
深圳“医疗卫生三名工程”项目(SZSM201612092)
深圳市科技研发资金项目(JCYJ20170307111755218)
广东省自然科学基金(2019A1515011290)
关键词
生物降解
镁合金
骨植入材料
表面改性
涂层
Biodegradation
Magnesium Alloy
Bone Implant Material
Surface Modification
Coating
