摘要
目的探讨后腹腔镜肾癌根治术治疗T2期肾癌的术中出血量和并发症。方法选取2016年12月至2018年12月间营口市中心医院收治的76例肾癌患者,根据治疗方法不同分为观察组和对照组,每组38例。采用开放性肾癌根治术治疗的纳入对照组,采用后腹腔镜肾癌根治术治疗的纳入观察组。比较两组患者的手术相关指标情况、治疗后7日炎性指标情况以及并发症发生情况。结果观察组患者术中出血量和住院时间比对照组少,手术时间比对照组多,差异均有统计学意义(均P<0.05)。观察组患者治疗后白细胞介素6(IL-6)和C反应蛋白(CRP)均低于对照组,差异均有统计学意义(均P<0.05)。两组患者治疗后的肿瘤坏死因子α和血沉比较,差异无统计学意义(P>0.05)。观察组患者的并发症发生率为7.9%,明显低于对照组患者的23.7%,差异有统计学意义(P<0.05)。结论后腹腔镜肾癌根治术治疗T2期肾癌,能减少患者的术中出血量,缩短住院时间,降低IL-6和CRP水平,减少并发症发生。
Objective To investigate the intraoperative blood loss and complications of retroperitoneal laparoscopic nephrectomy for stage T2 renal cell carcinoma.Methods From December 2016 to December 2018,76 patients with renal cell carcinoma were enrolled at Yingkou Central Hospital.The patients were randomly divided into an observation group and a control group with 38 patients in each group.The observation group underwent retroperitoneal laparoscopic nephrectomy and the control group underwent abdominal nephrectomy.The surgery related indexes,the levels of inflammatory markers at 7 d after the surgery and the incidence of complications were compared between the two groups.Results The intraoperative blood loss and length of hospital stay were significantly less in the observation group than in the control group(all P<0.05).The levels of interleukin-6(IL-6)and C-reactive protein(CRP)were significantly lower in the observation group than in the control group(all P<0.05).There was no significant difference in tumor necrosis factor-α(TNF-α)and erythrocyte sedimentation rate(ESR)between the two groups(P>0.05).The incidence of complications was 7.9%in the observation group,which was significantly lower than 23.7%of the control group(P<0.05)Conclusion Retroperitoneal laparoscopic nephrectomy for T2 renal cell carcinoma can significantly reduce intraoperative blood loss,shorten hospital stay,and reduce levels of IL-6 and CRP,and incidence of complications.
作者
袁晓光
王作江
刘建军
韩铁
YUAN Xiao-guang;WANG Zuo-jiang;LIU Jian-jun;HAN Tie(Department of Urology,Yingkou Central Hospital,Yingkou 115001,China)
出处
《中国肿瘤临床与康复》
2020年第2期211-213,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
后腹腔镜肾癌根治术
T2期肾癌
术中出血量
并发症
Retroperitoneal laparoscopic nephrectomy
Stage T2 renal cell carcinoma
Intraoperative blood loss
Complications
