摘要
目的探讨短期小剂量米力农治疗扩张型心肌病顽固性心衰的效果。方法选择我院60例2017年2月至2018年7月扩张型心肌病顽固性心衰患者。随机分组,常规药物治疗组采取常规药物治疗,米力农治疗组则采取常规药物联合短期小剂量米力农治疗。比较两组治疗效率;心室体积缩小时间、心室收缩力恢复正常的时间、水肿症状改善的时间、心功能改善两级时间;治疗前后患者每搏量、左心室射血分数、脑钠肽和左心室舒张末期内径;不良反应。结果米力农治疗组治疗效率、心室体积缩小时间、心室收缩力恢复正常的时间、水肿症状改善的时间、心功能改善两级时间、每搏量、左心室射血分数、脑钠肽和左心室舒张末期内径相比较常规药物治疗组更好,P<0.05。两组未见严重不良反应,P>0.05。结论常规药物联合短期小剂量米力农治疗扩张型心肌病顽固性心衰可获得较好预后。
Objective To investigate the effect of short-term low-dose milrinone in the treatment of refractory heart failure in dilated cardiomyopathy.Methods Sixty patients with refractory heart failure in dilated cardiomyopathy between February 2017 and July 2018 were enrolled in our hospital.Randomized,the conventional drug treatment group received conventional drug therapy,and the milrinone treatment group received conventional drugs combined with short-term low-dose milrinone treatment.The treatment efficiency was compared between the two groups;the time of ventricular volume reduction,the time when ventricular contractility returned to normal,the time of improvement of edema symptoms,and the improvement of cardiac function;the stroke volume,left ventricular ejection fraction,brain natriuretic peptide and left before and after treatment Ventricular end diastolic diameter;adverse reactions.Results The treatment efficiency,ventricular volume reduction time,ventricular contractility returned to normal time,edema symptom improvement time,cardiac function improvement two-stage time,stroke volume,left ventricular ejection fraction,brain natriuretic peptide and The left ventricular end diastolic diameter was better than the conventional drug treatment group,P<0.05.No serious adverse reactions were found in the two groups,P>0.05.Conclusion Conventional drugs combined with short-term low-dose milrinone can achieve better prognosis in the treatment of dilated cardiomyopathy with refractory heart failure.
作者
胡慧
HU Hui(Shandong Provincial First People’s Hospital of Jining,Jining,Shandong 272000)
出处
《智慧健康》
2020年第5期46-47,60,共3页
Smart Healthcare
关键词
短期小剂量米力农
扩张型心肌病顽固性心衰
效果
Short-term low-dose milrinone
Dilated cardiomyopathy refractory heart failure
Effect
