摘要
目的探究稀释及回收式自体输血与异体输血对脑动脉瘤患者手术的影响。方法收集2018年1月至2019年12月深圳市儿童医院收治的84例脑动脉瘤患者的临床资料,根据血液来源的不同将之分为自体回输组(X组)和异体输血组(Y组),每组各42例。观察并比较两组患者各自输血量,术后1d、7d血红蛋白(Hb)、红细胞计数(RBC)、血氧饱和度(SpO_(2))以及凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、C反应蛋白(CRP)、白介素-6(IL-6)等指标以及术后7d内输血不良反应发生情况。结果X组平均输血量为(776.84±31.35)mL,Y组平均输血量为(780.21±28.37)mL,差异无统计学意义(P>0.05);两组患者术后1d、7d检测Hb、RBC、SpO_(2)均较术前明显增高,(P<0.05);术后7d Hb、RBC、SpO_(2)的检测值与术后1d比较无显著性差异(P>0.05);X组术后1d、7d RBC的检测值与Y组同时间段比较显著升高(P<0.05)。两组患者PT、APTT、TT检测值各时间点比较差异无统计学意义(P>0.05),且各组术后1d、7d与术前水平比较差异无统计学意义(P>0.05);两组术后CRP、IL-6水平呈上升趋势,且X组上升幅度小于Y组,P<0.05;X组输血不良反应发生率为7.14%低于Y组的26.19%,P<0.05。结论脑动脉瘤患者手术中应用稀释及回收式自体输血更安全、携氧功能恢复更快、输血不良反应少,值得临床进一步推广。
Objective To explore the application value of dilution and recovery autotransfusion and allogeneic blood transfusion in the operation of cerebral aneurysms.Methods 84 patients with cerebral aneurysms in Shenzhen Children’s Hospital from January 2018 to December 2019 were selected as the research objects,and they were divided into autologous transfusion group(Group X)and allogeneic transfusion group(Group Y)according to different blood sources,with 42 cases in each group.The amount of blood transfusion,hemoglobin(HB),red blood cell count(RBC),blood oxygen saturation(SpO_(2)),prothrombin time(PT),alanine aminotransferase(ALT),total bilirubin(TBIL)and other indicators of the two groups were observed and recorded,as well as the occurrence of adverse reactions of blood transfusion within 7 days after operation.Results The average blood transfusion volume of group X was(776.84±31.35)mL,and that of group y was(780.21±28.37)mL,the difference was not statistically significant(P>0.05);the detection of Hb,RBC and SpO_(2)on postoperative 1d and 7d in the two groups were significantly higher than that before operation,and the difference was statistically significant(P<0.05);the detection of Hb,RBC and SpO_(2)on postoperative 7d in the two groups was significantly higher than that before operation,and the difference was statistically significant(P<0.05).There was no significant difference in the detection values of Hb,RBC and SpO_(2)between 1d and 7d after operation(P>0.05);the detection values of RBC in group X were significantly higher than those in group Y at the same time,and the difference was statistically significant(P<0.05).There was no significant difference in PT,ALT and TBIL between the two groups at each time point(P>0.05),and there was no significant difference in the levels of PT ALT and TBIL between the two groups at 1d and 7d after operation(P>0.05);the incidence of adverse reactions of blood transfusion in group X was 7.14%,which was lower than 26.19%in group Y,and the difference was statistically signific
作者
蒋一红
吴跃平
段立军
邹振梅
JIANG Yi-hong;WU Yue-ping;DUAN Li-jun;ZOU Zhen-mei(Shenzhen Children’s Hospital,Shenzhen,Guangdong 518026)
出处
《智慧健康》
2021年第25期69-71,共3页
Smart Healthcare
关键词
稀释
自体输血
异体输血
脑动脉瘤
Dilution
Autotransfusion
Allogeneic blood transfusion
Cerebral aneurysm
