摘要
TORCH感染,包括弓形虫(Toxoplasma gondii,TOX)、风疹病毒(Rubella virus,RUV)、巨细胞病毒(Cytomegalovirus,CMV)和单纯疱疹病毒(Herpes simplex virus,HSV),是育龄男女面临的重要公共卫生问题。这些病原体可通过母婴传播导致不孕、流产、死胎、死产及胎儿先天畸形等严重后果。本文深入探讨了TORCH感染的流行病学特征,揭示了其在不同年龄段、季节及地区的差异性分布,并强调了不良妊娠史与TORCH感染率之间的显著关联。同时,文章综述了TORCH感染的诊断方法,涵盖血清学检测、病原学检测及影像学与临床评估的综合运用。在治疗策略上,尽管多数病原体尚无特效疗法,但本文提出了针对性的干预措施,旨在减轻病情、降低传播风险。此外,本文还强调了孕前筛查、健康教育、疫苗接种及孕期监测与管理在TORCH感染预防与控制中的关键作用。通过综合分析TORCH感染的流行病学、诊断及治疗,为优化妊娠结局、提高人口素质提供了重要参考。
TORCH infection,including Toxoplasma gondii(TOX),Rubella virus(RUV),Cytomegalovirus(CMV),and Herpes simplex virus(HSV),is a significant public health issue in populations of men and women with childbearing age.These pathogens can cause serious consequences,such as infertility,miscarriage,stillbirth,and congenital malformations of the fetus,through mother to child transmission.This article delves into the epidemiological characteristics of TORCH infection,revealing its differential distributions across different age groups,seasons,and regions,and emphasizing the significant association between adverse pregnancy history and TORCH infection rate.Furthermore,the article reviews the diagnostic methods for TORCH infection,covering serological testing,pathogen detection,and the comprehensive application of imaging and clinical evaluation.In terms of treatment strategies,although most pathogens do not have specific therapies,this article proposes targeted intervention measures reducing the disease condition and lowering the risk of transmission.In addition,this article emphasizes the key roles of pre-pregnancy screening,health education,vaccination,and monitoring and management during pregnancy to facilitate the prevention and control of TORCH infection.By comprehensively analyzing the epidemiology,diagnosis,and treatment of TORCH infection,this article provides important references for optimizing pregnancy outcomes and improving population quality.
作者
徐东
翟艳红
李雷
曹正
XU Dong;ZHAI Yanhong;LI Lei;CAO Zheng(Department of Laboratory Medicine,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing Maternal and Child Health Care Hospital,Beijing 100026,China)
出处
《标记免疫分析与临床》
CAS
2024年第10期1952-1957,共6页
Labeled Immunoassays and Clinical Medicine
基金
北京妇产医院青年基金专项课题(编号:FCYYQN-2021)。
关键词
TORCH感染
流行病学
诊断
治疗
育龄男女
TORCH infection
Epidemiology
Diagnosis
Treatment
Men and women of childbearing age
