摘要
目的:观察变应性鼻炎对不同程度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的影响。方法:选取2018年3月至2021年5月揭阳市人民医院收治的变应性鼻炎(AR)伴不同程度OSAHS患者108例作为研究对象,按照疾病程度分为AR伴轻度OSAHS患者组、AR伴中度OSAHS患者组、AR伴重度OSAHS患者组,每组36例。采用鼻部症状视觉模拟评分法(VAS)比较AR患者治疗前后鼻部症状评分,包含鼻痒、鼻塞、流涕、喷嚏、鼻部整体症状、嗅觉障碍,评分0~10分;比较AR伴不同程度OSAHS患者治疗前后呼吸暂停低通气指数(AHI)与最低血氧饱和度(LSaO_(2));采用Epworth嗜睡量表(ESS)比较AR伴不同程度OSAHS患者治疗前后鼾声指数与ESS评分。结果:经过系统抗敏治疗后,所有AR患者的鼻部症状明显改善,且鼻痒、鼻塞、流涕、喷嚏、鼻部整体症状、嗅觉障碍的鼻部症状评分较治疗前降低,差异有统计学意义(均P<0.05);AR伴轻中度OSAHS患者治疗前后AHI与LSaO_(2)均显著改善,差异有统计学意义(均P<0.05),但AR伴重度OSAHS患者AHI与LSaO_(2)治疗前后无差异(P>0.05);AR伴轻度、中度、重度OSAHS患者治疗后鼾声指数、ESS评分均显著改善,差异有统计学意义(均P<0.05)。结论:经过系统抗敏治疗后AR患者鼻部症状明显改善,且AR伴OSAHS患者治疗后AHI、LSaO_(2)、鼾声指数、ESS评分均显著改善,但AR会加重OSAHS病情,加重患者白天嗜睡症状,影响血氧饱和度等。
Objective:To investigate the effect of allergic rhinitis on different degrees of obstructive sleep apnea hypopnea syndrome(OSAHS).Methods:A total of 108 patients with allergic rhinitis(AR)accompanied by OSAHS at Jieyang People′s Hospital from March 2018 to May 2021 were selected as the study subjects.According to the disease severity,the patients were divided into AR combined with mild OSAHS group,the patients with AR combined with moderate OSAHS group,and the patients with AR combined with severe OSAHS group,with 36 patients in each group.Visual Analogue Scale(VAS)of nasal symptoms was used to compare the scores of nasal symptoms in AR patients before and after treatment,including nasal itching,nasal congestion,runny nose,sneezing,overall nasal symptoms,and olfactory dysfunction,scoring 0~10.Apnea hypopnea index(AHI)and lowest oxygen saturation(LSaO_(2))of AR patients with different degrees of OSAHS before and after treatment were compared.Epworth Sleepiness Scale(ESS)scores of AR patients with different degrees of OSAHS before and after treatment was used to compare snoring index.Results:After systemic antisensitivity therapy,nasal symptoms of all AR patients were significantly improved,and the scores of nasal itching,nasal congestion,runny nose,sneezing,overall nasal symptoms,and nasal symptoms of olfactory dysfunction were reduced compared with before treatment,the differences were statistically significant(Ps<0.05).AHI and LSaO_(2) were significantly improved in AR patients with mild to moderate OSAHS before and after treatment,the difference was statistically significant(P<0.05),but there was no difference between AHI and LSaO_(2) in AR patients with severe OSAHS before and after treatment(P>0.05).Snoring index and ESS score of AR patients with mild,moderate and severe OSAHS were significantly improved after treatment,and the differences were statistically significant(Ps<0.05).Conclusion:After systematic antisensitivity therapy,nasal symptoms of AR patients were significantly improved,and AHI,LSaO_(2),sno
作者
徐展学
林楷生
袁炯聪
XU Zhanxue;LIN Kaisheng;YUAN Jiongcong(Jieyang People′s Hospital,Jieyang 522095,China)
出处
《世界睡眠医学杂志》
2022年第4期759-761,共3页
World Journal of Sleep Medicine
