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2010年-2016年日照市手足口病病原学分析 被引量:1

Etiological analysis of hand-foot-mouth disease in Rizhao during 2010-2016
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摘要 目的了解日照市HFMD的流行特征,为日照市手足口病的防治提供实验室病原学依据。方法对2010年-2016年日照市疾病预防控制中心收集的1 870份手足口病患者的粪便、咽拭子标本,通过荧光定量PCR方法进行肠道病毒核酸检测。结果 2010年-2016年共检测标本1 870份,其中核酸检测阳性标本1 533份,总阳性率为81.98%,其中EV71型病毒568份,占阳性总数的37.05%,CA16型519份,占阳性总数的33.86%,其他类型肠道病毒446份,占阳性总数的29.09%。结论导致手足口病流行的肠道病毒在每年的流行过程中的组成不同,有一定的规律,在男女患儿中的分布也不完全相同,同时在咽拭子和粪便中的分布也不相同。 Objective According to the laboratory results analysis of hand - toot - mouth disease(HFMD) , to understand the epidemiological characteristics of HFMD in Rizhao, so as to provide laboratory basis for the prevention of HFMD in Rizhao. Methods 1 870 stool and throat swab specimens collected from HFMD patients by Rizhao CDC were conducted for the determi- nation of enterovirus with real time - PCR. Results 1870 specimens of HFMD were detected during 2010 - 2016, amtmg which 1 533 specimens are enterovirus test positive, with the total positive rate of 81.98% , in which EV71 virus were detected in 568 copies, accounting for 37.05% of the total number of positive, CA16 virus were detected in 519 copies, accounting for 33.86% of the total number of positive, other types of enterovirus were detected in 446 copies, accounting for 29.09% of the total. Conclusion The causes of HFMD are different in every year with certain rules, and its distribution is different between male and female children, so is between in pharyngeal swabs and fecal ones.
作者 李超 周荣荣
出处 《中国卫生检验杂志》 CAS 2017年第11期1560-1562,共3页 Chinese Journal of Health Laboratory Technology
关键词 手足口病 荧光定量PCR 肠道病毒71型 柯萨奇病毒A16型 其他肠道病毒 Hand - foot - mouth disease Fluorescence quantitative PCR Enterovirus 71 Coxsaekie virus AI 6 Other entero- virus
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