摘要
目的:探讨头针对脑卒中后认知障碍患者治疗前后蒙特利尔认知功能评分(Mo CA)和血清同型半胱氨酸(Hcy)含量变化的影响。方法:将符合入选标准的90例患者随机分成对照组(认知训练组,A组)、按摩组(头部自我按摩+认知训练组,B组)、头针组(头针+认知训练组,C组),每组30例。分别检测3组患者治疗前、治疗15 d后Mo CA量表评分和血清Hcy含量。结果:3组患者治疗前、治疗15 d后Hcy含量比较示差异均无统计学意义(P>0.05);Mo CA评分比较示治疗前差异无统计学意义(P>0.05),治疗15 d后与B组比较,A组间差异无统计学意义(t_(A-B)=1.30,P>0.05);与C组比较,A组、B组间差异均有统计学意义(t_(A-C)=3.66,t_(B-C)=2.48,P均<0.05)。结论:头针治疗对脑卒中后认知障碍患者血清Hcy含量变化无影响,但可提高Mo CA评分,即改善脑卒中后认知障碍患者的认知功能,值得临床推广应用。
AIM:To investigate the effect of scalp acupuncture on the score of MoCA (Montreal cognitive function score effect) and serum of Hcy in stroke patients with cognitive disorder before and after treatment.METHODS:90 patients,who met the inclusion criteria were randomly divided into control group (cognitive training group),massage group (head self massage and cognitive training group),scalp acupuncture group (scalp acupuncture plus cognitive training group),30 cases in each group.The MoCA scale and content of Hcy in serum were evaluated before and after 15 d treatment respectively in three groups.RESULTS:Before and after 15 d treatment,the content of Hcy had no significant difference among three groups (all P 〉 0.05).Before treatment,the score of MoCA also had no significant difference among three groups.After treatment of 15 d,the score of MoCA had no significant difference between the control group and massage group (tA-B =1.30,P 〉 0.05);between the control group and scalp acupuncture group,massage group and scalp acupuncture group,the difference had statistically significant difference (tA-c =3.66,tB-c =2.48,P 〈 0.05).CONCLUSION:Scalp acupuncture treatment has no effect on the change of serum Hcy levels in stroke patients with cognitive impairment,but can improve the MoCA score,namely to improve cognitive function of stroke patients and it is worthy of clinical application.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2017年第2期165-169,共5页
Chinese Journal of Clinical Pharmacology and Therapeutics
基金
安徽省教育厅项目(KJ2013B312)