摘要
目的：探讨动态血糖监测在胰岛素瘤患者中的应用价值。方法选择本院2013年10月至2015年12月收治的胰岛素瘤患者16例为观察组,同期在本院确诊的2型糖尿病反应性低血糖患者15例为糖尿病组,健康体检正常的志愿者15例为对照组。上述三组均接受72 h动态血糖监测。比较各组一般资料、24 h血糖均值、标准差、最大血糖值、最小血糖值、最大波动幅度、低血糖发生次数和持续时间等。结果观察组BMI指数和胰岛素释放指数显著高于糖尿病组、对照组（ P〈0.05）。糖尿病组 HbAlc 显著高于观察组和对照组（ t=4.615、4.273,P〈0.05）,MAD则显著低于观察组和对照组（t=5.124、5.238,P〈0.05）。观察组72h饥饿-运动试验阳性13例,阴性3例。观察组平均血糖、最小血糖值分别为（4.69±1.53）mmol/L、（2.46±0.29）mmol/L,均显著低于糖尿病组和对照组（ P〈0.05）。观察组最大血糖值和最大波动幅度显著低于糖尿病组,但显著高于对照组（ P〈0.05）。观察组昼间、夜间和24 h内低血糖发生次数均显著多于糖尿病组,且低血糖持续时间显著长于糖尿病组（ P〈0.05）。结论动态血糖监测能够反映胰岛素瘤患者24 h内血糖动态变化,具有较大的应用价值。
Objective To explore the application value of dynamic blood glucose monitoring in the blood glu-cose monitoring for patients with insulinoma. Methods A total of 16 patients with insulinoma treated in our hospital from October 2013 to December 2015 were taken as the observation group. While 15 cases with hypoglycemia caused by the type 2 diabetic reaction were taken as the diabetic group and 15 cases of normal healthy volunteers as control group. Three groups all received 72 hours dynamic blood glucose monitoring. The general information, the mean value of 24 hours blood glucose, the standard deviation of the blood glucose, the maximum of the blood sugar, the minimum of the blood sugar, the maximum fluctuation range and the frequency and duration of hypoglycemia were compared. Results The BMI index and insulin releasing index of the observation group were significantly higher than that of the diabetic group and the control group （ P〈0. 05 ） . The HbAlc of diabetic group was significantly higher than that of the observa-tion group and control group （ t=4. 615 , 4. 273 , P〈0. 05 ） , while the MAD of the diabetic group was significantly lower than that of the observation group and control group （ t=5. 124 , 5. 238 , P〈0. 05 ） . The 72-hour starvation-exercise test found 13 positive cases and 3 negative cases in the observation group. The average blood glucose and blood glucose of the observation group were （4. 69 ＋1. 53） mmol/L and （2. 46 ＋0. 29） mmol/L respectively, which were significantly low-er than that of the diabetic group and the control group （ P〈0. 05 ） . The maximum blood glucose level and the maximum fluctuation range of the observation group were significantly lower than that of the diabetic group, which were significant-ly higher than that of the control group （ P〈0. 05 ） . The frequency of hypoglycemia of observation group was significantly higher than that of the diabetic group and the duration of hypoglycemia was significantly longer than that of the diabetic
作者
李胜超
李妙
吴海洋
李文
Li Shengchao Li Miao Wu Haiyang Li Wen(Department of Hepatobiliary Surgery, the Fourth Hospital of Hebei Medical University, Shifiazhuang 050000, Chin)
出处
《国际护理学杂志》
2016年第20期2753-2755,F0004,共4页
international journal of nursing
关键词
胰岛素瘤
血糖监测
动态血糖监测
运用价值
Insulinoma
Blood glucose monitoring
Dynamic blood glucose monitoring
Application value
