摘要
目的研究环磷腺苷和参麦注射液联合治疗老年冠心病慢性心力衰竭的临床疗效。方法选取我院2012年3月至2014年4月收治的老年冠心病慢性心力衰竭患者140例,随机分为实验组和对照组。对照组采取常规抗心衰治疗;实验组在此基础上联合环磷腺苷和参麦注射液治疗,治疗2周后观察两组患者的左室射血分数(LVEF)、左室舒张末径(LVEDD)、舒张早期/晚期最大血流速度比值(E/A)、血浆脑钠肽(BNP)及其临床疗效。结果治疗2周后,实验组总有效率(91.43%)明显优于对照组(75.71%),差异具有统计学意义(P<0.05)。两组各指标(除对照组LVEDD和E/A)均较治疗前有明显改善,并且实验组各项指标均明显优于对照组,差异具有统计学意义(P<0.05)。结论环磷腺苷联合参麦注射液在治疗老年冠心病慢性心力衰竭上临床疗效显著。
Objective To investigate the clinical curative effect of adenosine cyclophosphate and Shenmai injection in the treatment of senile coronary heart disease（CHD） patients with chronic heart failure（CHF）. Methods 140 aged CHD patients diagnosed with CHF were randomly divided into experimental group and control group. The control group received conventional anti heart failure treatment,while the experimental group received combined therapy of adenosine cyclophosphate and Shenmai injection on the basis of conventional therapy. The left ventricular ejection fraction（LVEF）, left ventricular end-diastolic diameter（LVEDD）, E peak of diastolic early flowvelocity/A peak of diastolic later flow-velocity（E/A）, brain natriuretic peptide（BNP） and clinical efficacy were observed and compared between two groups. Results After 2 weeks of therapy, the total effective rate of experimental group was 91.43%, significantly higher than75.71% of control group（P〈0.05）. The LVEF, LVEDD, E/A ratio and BNP of experimental group improved significantly after therapy（P0.05）, and were significant better than those of control group after therapy（P〈0.05）. The LVEF and BNP of control group improved significantly after therapy（P〈0.05）, but there were no statistical differences in LVEDD and E/A ratio. Conclusions Adenosine cyclophosphate combined with Shenmai injection is effective in the treatment of senile chronic heart failure of coronary heart disease.
出处
《临床医学工程》
2015年第3期321-322,共2页
Clinical Medicine & Engineering
关键词
环磷腺苷
参麦注射液
冠心病
慢性心力衰竭
Adenosine cyclophosphate
Shenmai injection
Coronary heart disease
Chronic heart failure
