摘要
目的 探讨原发性胃非何杰金淋巴瘤 (PG -NHL)的临床特点 ,提高其诊治水平。方法 分析 8例PG -NHL的临床资料 ,探讨其临床特点。结果 8例患者平均年龄 45 .6岁 ,临床表现以腹痛多见。胃镜下活检诊为PG -NHL2例 (阳性率 2 5 % )。病理类型均为B细胞性。PG -NHL胃镜下表现严重或呈多中心起源而临床表现轻 ,好发于胃体。手术能确诊及分期。结论 PG -NHL常规活检阳性率低 ,易误诊 ,提高对其临床特点的认识 ,结合较为敏感的活检方法 ,有望提高其确诊率。手术对于ⅠE、ⅡE期PG -NHL应作为首选。
Objective To evaluate the clinical features of primary gastric non-Hodgkin lymphoma(PG-NHL) and improve its diagnosis and clinical outcome. Methods The clinical data of 8 patients with PG-NHL were retrospectively reviewed. Results Median age of patients was 45.6(range 18～64). The clinical manifestations were abdominal pain, hematemesis, melena, nausea, vomiting, burping. Two out of eight patients were confirmed by routine endoscopic biopsy. All patients were of B-cell origin. Endoscopic findings of PG-NHL were similar to that found in gastric cancer or ulcer. PG-NHL had lighter symptoms in comparison with gastric cancer, but endoscopic appearance was more serious, and some of them showed multicentric origin which was seen frequently at gastric corpus, otherwise, there was no metastases observed in gastric cancer. Operation was able to help to confirm diagnosis and clinical stage and prevent complication. Conclusion Because of low morbidity and high false negativity in routine biopsies, PG-NHL is hard to be diagnosed. Our studies indicates that knowledge of its clinical features together with more sensitive bioptic means might be important in diagnosis and patients got beneficial from surgical management, especially for those in stages IE and ⅡE .
出处
《苏州医学院学报》
2001年第2期152-153,共2页
Acta Academiae Medicinae Suzhou
