摘要
目的评估入院时静息呼吸频率与全球急性冠状动脉事件注册评分系统(GRACE)评分在急性冠脉综合征(ACS)风险分层中的作用和价值。方法前瞻性的收集符合纳入标准的ACS患者,在入院时检测患者呼吸频率并进行GRACE评分,根据呼吸频率分级和GRACE评分分级进行分组,观察近期心血管疾病病死率。随访时间为30d。结果死亡组呼吸频率明显高于存活组。Kapian-Meier生存曲线分析揭示呼吸频率和GRACE危险积分高者近期预后明显较差;多变量Cox比例风险模型表明GRACE危险积分和呼吸频率是ACS患者近期病死率的独立危险因素。结论入院时静息呼吸频率与GRACE评分联合对ACS患者危险分层具有重要的临床应用价值,可用于近期死亡风险预警。
Objective The aim of this study is to assess the value of respiratory rate and Global Registry of Acute Coronary E- vents(GRACE) scoring system in risk stratification with Acute Coronary Syndrome(ACS). Methods This study included patients with ACS. They were grouped according to respiratory rate and GRACE score. The patients with ACS met the inclusion criteria were detected for respiratory rate and GRACE score at the time of admissiom the recent mortality of patients with ACS had been observed by follow-up. The follow-up time was 30 days. Results The respiratory rate in the death group were higher than that in the surviving group. The results revealed the higher the respiratory rate and GRACE risk score, the worse the prognosis by using Kapian-Meier survival curve analysis. GRACE risk score and respiratory rate in patients with ACS were independent risk factors for recent cardiovascular mortality in multivariate Cox proportional hazard model. Conclusion The resting respiratory rate and GRACE score have important clinical value for risk stratification of ACS patients,which could he used for the risk warning of recent death.
出处
《重庆医学》
CAS
CSCD
北大核心
2013年第21期2478-2480,共3页
Chongqing medicine