摘要
目的:总结妊娠滋养细胞肿瘤的诊治经验。方法:总结我院于2000年至2008年间收治的46例妊娠滋养细胞肿瘤患者的诊疗资料。结果:侵蚀性葡萄胎39例,其中Ⅰ期25例,Ⅱ期11例,Ⅲ期3例;38例经化疗达到临床治愈,1例因化疗副反应放弃继续化疗,但定期随访临床转归良好,达到治愈的标准,总治愈率100%。绒毛膜癌7例,其中Ⅰ期4例,Ⅱ期1例,Ⅲ期2例;3例经化疗达到临床治愈,2例因化疗副反应放弃继续化疗,定期随访临床转归良好,达到治愈的标准,1例化疗耐药,无生育要求行全子宫切除术,1例因肺转移病灶持续存在转院行肺叶切除术,总治愈率85.7%。结论:恶性滋养细胞肿瘤对化疗敏感,是可通过化疗治愈的肿瘤,随着诊疗技术的提高,治疗的个体化可减少化疗的毒副反应。
Objective： To observe the effects of different treatment measures on the prognosis of gestational trophoblastic tumor.Methods： A total of 46 cases of gestational trophoblastic tumor from 2000 to 2008 in our hospital were analyzed retrospectively.Results： Invasive mole,39 cases of which 25 cases of stage Ⅰ,11 cases of stage Ⅱ and 3 cases of stage Ⅲ,38 cases of chemotherapy to achieve clinical cure,1 patient with side effects gave up chemotherapy,but regular follow-up of good clinical outcomes to the standard cure,the total cure rate was 100%;7 cases choriocarcinoma,including four cases of stage Ⅰ,1 case of stage Ⅱ,2 cases of stage Ⅲ,3 patients achieved clinical cure after chemotherapy,2 patients gave up due to chemotherapy side effects,regular follow-up clinical outcome was good at healing the standard,one case of resistance to chemotherapy,no growth requirements with a hysterectomy,1 patient with lung metastases persist referral line lobectomy,total cure rate of 85.7%.Conclusion： Gestational trophoblastic tumor is sensitive to chemotherapy,which can be cured by chemotherapy.Individualized treatment can reduce the toxic side effects.
出处
《现代医学》
2012年第4期423-425,共3页
Modern Medical Journal
关键词
妊娠滋养细胞肿瘤
侵蚀性葡萄胎
绒毛膜癌
化疗
治疗个体化
gestational trophoblastic tumor
invasive mole
choriocarcinoma
chemotherapy
individualized treatment
