摘要
采用镀钢镉还原测定沿检测57倒腹水患者血清和腹水中一氧化氮(NO)水平,并动态监测其中19例肝硬化H发性细菌性腹膜炎(SBP)患者治疗前后血和腹水NO水平及腹水NO与血NO比值(NOA/NOB)变化。结果显示:肝硬化SBP漏出性腹水组中,腹水NO水平和NOA/NOB值明显高于漏出性腹水组。若以NOA/NOB≥1.1为阳性判别值,诊断SBP的敏感性为81.5%,特异性为89.5%。19例SBP患者经抗感染治疗后,腹水NO水平和NOA/NOB比值较治疗前明显降低。表明动态监测肝硬化患者腹水与血清NO水平和二者比值的变化,对肝硬化SBP的诊断和预后判断均有一定价值。
ln the present study, levels of nitric oxide (NO) in ascites and blood were determined by activated cadminum in 57 patients with ascites. During the treatment, levels of NO in ascites and blood, ratio of NO in ascites and blood (NOA/NOB) of 19 cirrhosis patients with spontaneous bacterial peritonitis (SBP) were consecutively determined. The results showed that the levels of NO in ascites and NOA/NOB in 19 cirrhosis cases with SBP were sigtnificantly higher than those of 38 cases with ascites transudate, and lower significantly after the effcctive antiinfection treatment. With numerical value ≥ 1.1. as positive discrimination ratio, the sensitivity and specificity of NO/NO in detecting SBP of cirrhosis were 81.5 % and 89.5% respectively. lt suggested that determining and monitoring the levels of NO in ascites and blood, and ratio of NOA/NOB could be used to diagnose SBP of cirrhosis and predicate the prognosis.
出处
《重庆医科大学学报》
CAS
CSCD
1998年第1期51-53,共3页
Journal of Chongqing Medical University