摘要
目的了解非淋菌性尿道炎(NGU)中支原体感染的情况及对药物耐药性的状况。方法对414例NGU患者的分泌物、前列腺液等进行支原体培养、鉴定、计数及药敏试验。结果414例中支原体阳性284例,感染率为68.60%;解脲脲支原体(Uu)、人支原体(Mh)及Uu+Mh混合感染的阳性率分别为21.74%(90例)、12.56%(52例)、34.30%(142例);支原体对12种抗菌药物敏感性最高的是米诺环素(76.76%),其次是多西环素(73.24%);耐药性最高的为环丙沙星(77.46%)、司帕沙星(68.31%)、红霉素(68.31%)。结论NGU患者支原体感染率高,以Uu+Mh混合感染为主;且对环丙沙星、司帕沙星等药物的耐药性呈上升趋势,并出现多药耐药性;因此,对NGU患者,加强支原体培养和药敏试验,对指导临床用药,最大限度地控制耐药菌株的产生,尤为重要。
OBJECTIVE To investigate the infection of Mycoplasma and drug resistance in the patients of nongonococcal urethritis （NGU）in the local area. METHODS Totally 414 specimens in the patients of NGU were collected, cultured and tested for drug sensitvity. RESULTS From them there were 284 patients who had Mycoplasma （68.60%）. The simple infection of Ureaplasma urealyticum （Uu）was 90 cases （21. 74%） and that of Mycoplasma hominis （Mh） was 52 cases （12. 56%）. The mixed was 142 cases （34.30%）. The result of drug sensitivity showed that sensitivity of Mycoplasma to minocycline （Minocin） was the highest, then was to doxycycline. Ciprofloxacin was with the highest drug resistance, then were sparfloxacin and erythromycin. CONCLUSIONS The infection rate of Mycoplasma in the patients of NGU is in a rising tendency% Mycoplasma are severely resistant to ciprofloxacin, sparfloxacin, and erythromycin, and have multi-resistance. It is important to culture and test the drug sensitivity of Mycoplasma. To control the Mycoplasma infection and supervision management of antibiotics is a urged and important task for us.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2008年第1期134-136,共3页
Chinese Journal of Nosocomiology
关键词
非淋菌性尿道炎
支原体
药敏
耐药性
Nongonococcal urethritis
Mycoplasma
Drug sensitivity
Drug resistance
