摘要
目的探讨妊娠合并梅毒的治疗对围产儿预后的影响。方法根据妊娠期是否行全疗程抗梅毒治疗,将68例经血清学检查确诊为梅毒的孕妇分为治疗组和未治疗组,比较两组孕妇的妊娠结局、围产儿预后及新生儿先天梅毒的发生情况。结果治疗组足月分娩率为84.38%,而未治疗组仅为41.67%(P<0.01);治疗组早产及死胎的发生率分别为12.50%和3.13%,明显低于未治疗组的36.11%和22.22%(P<0.01);治疗组分娩正常新生儿者占64.52%,而未治疗组仅占28.57%(P<0.01)。结论妊娠期梅毒患者及早规范的抗梅毒治疗,可以降低围产儿的死亡率及先天梅毒的发生;孕期常规梅毒筛查特别重要。
Objective To analyze the effect of treatment of pregnant women with syphilis on perinatal prognosis. Methods Sixty- eight pregnant women with syphilis serologicaUy confirmed were divided into treatment group and control group based on whether given full course of treatment during pregnancy. The gestational outcomes, perinatal prognosis and the occurrence of congenital syphilis between the two groups were compared. Results Term delivery reaehed 84.38 % in treatment group and only 41.67% in control group （P 〈 0.01）. The rate of premature birth and fetal intrauterine death were 12.50% and 3.13% in treatment group sigficantly lower than 36.11% and 22.22% in control group （ P 〈 0.01 ）. The normal rate of neonates was 64.52% in treatment group , significantly higher than that of 28.57 % in the control group （ P 〈0.01 ）. Conclusion Regular and early treatment of pregnant women with syphilis can reduce the perinatal mortality and the incidence of congenital syphilis. Therefore routine screening of syphilis in pregnant women is particularly important for perinatal health.
出处
《中国热带医学》
CAS
2007年第6期951-951,962,共2页
China Tropical Medicine
基金
汕头市科技计划项目(汕府科[2005]116号)
关键词
梅毒
妊娠
治疗
梅毒螺旋体
先天性
Syphilis
Complications due to Pregnancy
Syphilis
Perinatal prognosis
