摘要
目的:探讨冠心病患者动脉僵硬度与其心功能状态的关系。方法:130例确诊冠心病患者,其中男80例,女50例,平均年龄(63.57±9.42)岁(范围40~80岁),按纽约心功能分级标准进行分级,根据不同的心功能分四组,心功能Ⅰ、Ⅱ、Ⅲ、Ⅳ级作为实验组,与实验组性别、年龄匹配的105例健康人作为正常对照组。采用脉搏波传导速度(Pu lse wave velocity,PWV)自动测定系统对上述人群测定颈动脉-股动脉PWV(cfPWV)作为反映动脉僵硬度的指标,比较正常人与不同心功能状态冠心病患者间动脉僵硬度的差异。结果:在调整了年龄、性别、血压、血糖和血脂参数之后,分析结果显示,心功能与cfPWV值呈显著正相关(P<0.01),随心功能的恶化cfPWV值逐渐增加。正常人和纽约心功能Ⅰ、Ⅱ、Ⅲ、Ⅳ及患者的cfPWV值分别为(8.62±0.82)m/s,(9.97±1.26)m/s,(11.82±1.84)m/s,(14.93±1.44)m/s,(16.56±1.64)m/s。结论:PWV所反映的动脉僵硬度增加在冠心病患者中与心功能状态恶化相关,改善动脉僵硬度可能对于改善心功能有益。
Objective:To explore the relationship between arterial stiffness and cardiac function in patients with coronary heart disease.Methods:130 patients with coronary artery disease were included in our study,80 of them were male,50 of them were female,mean age(63.57±9.42) years(range 40~80 years),according to the New York Heart Association cardiac function classification,divided into four groups,the cardiac function I、II、III、IV level acted as the experimental group,105 sex and age matched healthy people acted as...
出处
《中国民康医学》
2008年第3期185-187,189,共4页
Medical Journal of Chinese People’s Health
基金
卫生部十年百项"血管病变早期检测技术推广"项目支助(项目编号:04-10-01)
关键词
脉搏波传导速度
冠心病
心功能
Pulse wave velocity
Coronary disease
Cardiac function
