Over the past years,many efforts have been accomplished to achieve fast and accurate meta-heuristic algorithms to optimize a variety of real-world problems.This study presents a new optimization method based on an unu...Over the past years,many efforts have been accomplished to achieve fast and accurate meta-heuristic algorithms to optimize a variety of real-world problems.This study presents a new optimization method based on an unusual geological phenomenon in nature,named Geyser inspired Algorithm(GEA).The mathematical modeling of this geological phenomenon is carried out to have a better understanding of the optimization process.The efficiency and accuracy of GEA are verified using statistical examination and convergence rate comparison on numerous CEC 2005,CEC 2014,CEC 2017,and real-parameter benchmark functions.Moreover,GEA has been applied to several real-parameter engineering optimization problems to evaluate its effectiveness.In addition,to demonstrate the applicability and robustness of GEA,a comprehensive investigation is performed for a fair comparison with other standard optimization methods.The results demonstrate that GEA is noticeably prosperous in reaching the optimal solutions with a high convergence rate in comparison with other well-known nature-inspired algorithms,including ABC,BBO,PSO,and RCGA.Note that the source code of the GEA is publicly available at https://www.optim-app.com/projects/gea.展开更多
The reconstitution of a fully organized and functional hair follicle from dissociated cells propagated under defined tissue culture conditions is a challenge stillpending in tissue engineering. The loss of hair follic...The reconstitution of a fully organized and functional hair follicle from dissociated cells propagated under defined tissue culture conditions is a challenge stillpending in tissue engineering. The loss of hair follicles caused by injuries or pathologies such as alopecia not only affects the patients' psychological well-being, but also endangers certain inherent functions of the skin. It is then of great interest to find different strategies aiming to regenerate or neogenerate the hair follicle under conditions proper of an adult individual. Based upon current knowledge on the epithelial and dermal cells and their interactions during the embryonic hair generation and adult hair cycling, many researchers have tried to obtain mature hair follicles using different strategies and approaches depending on the causes of hair loss. This review summarizes current advances in the different experimental strategies to regenerate or neogenerate hair follicles, with emphasis on those involving neogenesis of hair follicles in adult individuals using isolated cells and tissue engineering. Most of these experiments were performed using rodent cells, particularly from embryonic or newborn origin. However, no successful strategy to generate human hair follicles from adult cells has yet been reported. This review identifies several issues that should be considered to achieve this objective. Perhaps the most important challenge is to provide threedimensional culture conditions mimicking the structure of living tissue. Improving culture conditions that allow the expansion of specific cells while protecting their inductive properties, as well as methods for selecting populations of epithelial stem cells, should give us the necessary tools to overcome the difficulties that constrain human hair follicle neogenesis. An analysis of patent trends shows that the number of patent applications aimed at hair follicle regeneration and neogenesis has been increasing during the last decade. This field is attractive not only to academic researchers展开更多
1.The need to develop a holographic digital mannequin Life processes,including high intelligence,self-organization,and homeostasis,are characterized by the biological organism in the form of self-renewal,self-replicat...1.The need to develop a holographic digital mannequin Life processes,including high intelligence,self-organization,and homeostasis,are characterized by the biological organism in the form of self-renewal,self-replication and self-regulation,metabolism,self-repair,and self-reproduction,which are all processes of multisystem coordinated movement[1].Research in the field of life sciences is not limited to the use of advanced observational methods to reveal microscopic structures at the subcellular or molecular level.Discoveries based on these methods alone cannot characterize the dynamic processes of life at the microscopic and molecular level[2].展开更多
Heart disease remains a leading cause of morbidity and mortality worldwide,highlighting the need for improved diagnostic methods.Traditional diagnostics face limitations such as reliance on single-modality data and vu...Heart disease remains a leading cause of morbidity and mortality worldwide,highlighting the need for improved diagnostic methods.Traditional diagnostics face limitations such as reliance on single-modality data and vulnerability to apparatus faults,which can reduce accuracy,especially with poor-quality images.Additionally,these methods often require significant time and expertise,making them less accessible in resource-limited settings.Emerging technologies like artificial intelligence and machine learning offer promising solutions by integrating multi-modality data and enhancing diagnostic precision,ultimately improving patient outcomes and reducing healthcare costs.This study introduces Heart-Net,a multi-modal deep learning framework designed to enhance heart disease diagnosis by integrating data from Cardiac Magnetic Resonance Imaging(MRI)and Electrocardiogram(ECG).Heart-Net uses a 3D U-Net for MRI analysis and a Temporal Convolutional Graph Neural Network(TCGN)for ECG feature extraction,combining these through an attention mechanism to emphasize relevant features.Classification is performed using Optimized TCGN.This approach improves early detection,reduces diagnostic errors,and supports personalized risk assessments and continuous health monitoring.The proposed approach results show that Heart-Net significantly outperforms traditional single-modality models,achieving accuracies of 92.56%forHeartnetDataset Ⅰ(HNET-DSⅠ),93.45%forHeartnetDataset Ⅱ(HNET-DSⅡ),and 91.89%for Heartnet Dataset Ⅲ(HNET-DSⅢ),mitigating the impact of apparatus faults and image quality issues.These findings underscore the potential of Heart-Net to revolutionize heart disease diagnostics and improve clinical outcomes.展开更多
The article describes a new method for malware classification,based on a Machine Learning(ML)model architecture specifically designed for malware detection,enabling real-time and accurate malware identification.Using ...The article describes a new method for malware classification,based on a Machine Learning(ML)model architecture specifically designed for malware detection,enabling real-time and accurate malware identification.Using an innovative feature dimensionality reduction technique called the Interpolation-based Feature Dimensionality Reduction Technique(IFDRT),the authors have significantly reduced the feature space while retaining critical information necessary for malware classification.This technique optimizes the model’s performance and reduces computational requirements.The proposed method is demonstrated by applying it to the BODMAS malware dataset,which contains 57,293 malware samples and 77,142 benign samples,each with a 2381-feature vector.Through the IFDRT method,the dataset is transformed,reducing the number of features while maintaining essential data for accurate classification.The evaluation results show outstanding performance,with an F1 score of 0.984 and a high accuracy of 98.5%using only two reduced features.This demonstrates the method’s ability to classify malware samples accurately while minimizing processing time.The method allows for improving computational efficiency by reducing the feature space,which decreases the memory and time requirements for training and prediction.The new method’s effectiveness is confirmed by the calculations,which indicate significant improvements in malware classification accuracy and efficiency.The research results enhance existing malware detection techniques and can be applied in various cybersecurity applications,including real-timemalware detection on resource-constrained devices.Novelty and scientific contribution lie in the development of the IFDRT method,which provides a robust and efficient solution for feature reduction in ML-based malware classification,paving the way for more effective and scalable cybersecurity measures.展开更多
Emerging technologies such as edge computing,Internet of Things(IoT),5G networks,big data,Artificial Intelligence(AI),and Unmanned Aerial Vehicles(UAVs)empower,Industry 4.0,with a progressive production methodology th...Emerging technologies such as edge computing,Internet of Things(IoT),5G networks,big data,Artificial Intelligence(AI),and Unmanned Aerial Vehicles(UAVs)empower,Industry 4.0,with a progressive production methodology that shows attention to the interaction between machine and human beings.In the literature,various authors have focused on resolving security problems in UAV communication to provide safety for vital applications.The current research article presents a Circle Search Optimization with Deep Learning Enabled Secure UAV Classification(CSODL-SUAVC)model for Industry 4.0 environment.The suggested CSODL-SUAVC methodology is aimed at accomplishing two core objectives such as secure communication via image steganography and image classification.Primarily,the proposed CSODL-SUAVC method involves the following methods such as Multi-Level Discrete Wavelet Transformation(ML-DWT),CSO-related Optimal Pixel Selection(CSO-OPS),and signcryption-based encryption.The proposed model deploys the CSO-OPS technique to select the optimal pixel points in cover images.The secret images,encrypted by signcryption technique,are embedded into cover images.Besides,the image classification process includes three components namely,Super-Resolution using Convolution Neural Network(SRCNN),Adam optimizer,and softmax classifier.The integration of the CSO-OPS algorithm and Adam optimizer helps in achieving the maximum performance upon UAV communication.The proposed CSODLSUAVC model was experimentally validated using benchmark datasets and the outcomes were evaluated under distinct aspects.The simulation outcomes established the supreme better performance of the CSODL-SUAVC model over recent approaches.展开更多
Nowadays,Internet of Things(IoT)has penetrated all facets of human life while on the other hand,IoT devices are heavily prone to cyberattacks.It has become important to develop an accurate system that can detect malic...Nowadays,Internet of Things(IoT)has penetrated all facets of human life while on the other hand,IoT devices are heavily prone to cyberattacks.It has become important to develop an accurate system that can detect malicious attacks on IoT environments in order to mitigate security risks.Botnet is one of the dreadfulmalicious entities that has affected many users for the past few decades.It is challenging to recognize Botnet since it has excellent carrying and hidden capacities.Various approaches have been employed to identify the source of Botnet at earlier stages.Machine Learning(ML)and Deep Learning(DL)techniques are developed based on heavy influence from Botnet detection methodology.In spite of this,it is still a challenging task to detect Botnet at early stages due to low number of features accessible from Botnet dataset.The current study devises IoT with Cloud Assisted Botnet Detection and Classification utilizingRat SwarmOptimizer with Deep Learning(BDC-RSODL)model.The presented BDC-RSODL model includes a series of processes like pre-processing,feature subset selection,classification,and parameter tuning.Initially,the network data is pre-processed to make it compatible for further processing.Besides,RSO algorithm is exploited for effective selection of subset of features.Additionally,Long Short TermMemory(LSTM)algorithm is utilized for both identification and classification of botnets.Finally,Sine Cosine Algorithm(SCA)is executed for fine-tuning the hyperparameters related to LSTM model.In order to validate the promising 3086 CMC,2023,vol.74,no.2 performance of BDC-RSODL system,a comprehensive comparison analysis was conducted.The obtained results confirmed the supremacy of BDCRSODL model over recent approaches.展开更多
Colorectal carcinoma(CRC)is one such dispersed cancer globally and also prominent one in causing cancer-based death.Conventionally,pathologists execute CRC diagnosis through visible scrutinizing under the microscope t...Colorectal carcinoma(CRC)is one such dispersed cancer globally and also prominent one in causing cancer-based death.Conventionally,pathologists execute CRC diagnosis through visible scrutinizing under the microscope the resected tissue samples,stained and fixed through Haematoxylin and Eosin(H&E).The advancement of graphical processing systems has resulted in high potentiality for deep learning(DL)techniques in interpretating visual anatomy from high resolution medical images.This study develops a slime mould algorithm with deep transfer learning enabled colorectal cancer detection and classification(SMADTL-CCDC)algorithm.The presented SMADTL-CCDC technique intends to appropriately recognize the occurrence of colorectal cancer.To accomplish this,the SMADTLCCDC model initially undergoes pre-processing to improve the input image quality.In addition,a dense-EfficientNet technique was employed to extract feature vectors from the pre-processed images.Moreover,SMA with Discrete Hopfield neural network(DHNN)method was applied for the recognition and classification of colorectal cancer.The utilization of SMA assists in appropriately selecting the parameters involved in the DHNN approach.A wide range of experiments was implemented on benchmark datasets to assess the classification performance.A comprehensive comparative study highlighted the better performance of the SMADTL-CDC model over the recent approaches.展开更多
Liver cancer is one of the major diseases with increased mortality in recent years,across the globe.Manual detection of liver cancer is a tedious and laborious task due to which Computer Aided Diagnosis(CAD)models hav...Liver cancer is one of the major diseases with increased mortality in recent years,across the globe.Manual detection of liver cancer is a tedious and laborious task due to which Computer Aided Diagnosis(CAD)models have been developed to detect the presence of liver cancer accurately and classify its stages.Besides,liver cancer segmentation outcome,using medical images,is employed in the assessment of tumor volume,further treatment plans,and response moni-toring.Hence,there is a need exists to develop automated tools for liver cancer detection in a precise manner.With this motivation,the current study introduces an Intelligent Artificial Intelligence with Equilibrium Optimizer based Liver cancer Classification(IAIEO-LCC)model.The proposed IAIEO-LCC technique initially performs Median Filtering(MF)-based pre-processing and data augmentation process.Besides,Kapur’s entropy-based segmentation technique is used to identify the affected regions in liver.Moreover,VGG-19 based feature extractor and Equilibrium Optimizer(EO)-based hyperparameter tuning processes are also involved to derive the feature vectors.At last,Stacked Gated Recurrent Unit(SGRU)classifier is exploited to detect and classify the liver cancer effectively.In order to demonstrate the superiority of the proposed IAIEO-LCC technique in terms of performance,a wide range of simulations was conducted and the results were inspected under different measures.The comparison study results infer that the proposed IAIEO-LCC technique achieved an improved accuracy of 98.52%.展开更多
The zebrafish has become a popular vertebrate animal model in biomedical research.However,it is still challenging to make conditional gene knockout(CKO)models in zebrafish due to the low efficiency of homologous recom...The zebrafish has become a popular vertebrate animal model in biomedical research.However,it is still challenging to make conditional gene knockout(CKO)models in zebrafish due to the low efficiency of homologous recombination(HR).Here we report an efficient non-HR-based method for generating zebrafish carrying a CKO and knockin(KI)switch(zCKOIS)coupled with dual-color fluorescent reporters.Using this strategy,we generated hey2^zCKOIS which served as a hey2 KI reporter with EGFP expression.Upon Cre induction in targeted cells,the hey2^zCKOIS was switched to a non-functional CKO allele hey2^zCKOIS-inv associated with Tag RFP expression,enabling visualization of the CKO alleles.Thus,simplification of the design,and the visibility and combination of both CKO and KI alleles make our z CKOIS strategy an applicable CKO approach for zebrafish.展开更多
Rapid advancements of the Industrial Internet of Things(IIoT)and artificial intelligence(AI)pose serious security issues by revealing secret data.Therefore,security data becomes a crucial issue in IIoT communication w...Rapid advancements of the Industrial Internet of Things(IIoT)and artificial intelligence(AI)pose serious security issues by revealing secret data.Therefore,security data becomes a crucial issue in IIoT communication where secrecy needs to be guaranteed in real time.Practically,AI techniques can be utilized to design image steganographic techniques in IIoT.In addition,encryption techniques act as an important role to save the actual information generated from the IIoT devices to avoid unauthorized access.In order to accomplish secure data transmission in IIoT environment,this study presents novel encryption with image steganography based data hiding technique(EISDHT)for IIoT environment.The proposed EIS-DHT technique involves a new quantum black widow optimization(QBWO)to competently choose the pixel values for hiding secrete data in the cover image.In addition,the multi-level discrete wavelet transform(DWT)based transformation process takes place.Besides,the secret image is divided into three R,G,and B bands which are then individually encrypted using Blowfish,Twofish,and Lorenz Hyperchaotic System.At last,the stego image gets generated by placing the encrypted images into the optimum pixel locations of the cover image.In order to validate the enhanced data hiding performance of the EIS-DHT technique,a set of simulation analyses take place and the results are inspected interms of different measures.The experimental outcomes stated the supremacy of the EIS-DHT technique over the other existing techniques and ensure maximum security.展开更多
Test selection is to select the test set with the least total cost or the least total number from the alternative test set on the premise of meeting the required testability indicators.The existing models and methods ...Test selection is to select the test set with the least total cost or the least total number from the alternative test set on the premise of meeting the required testability indicators.The existing models and methods are not suitable for system level test selection.The first problem is the lack of detailed data of the units’fault set and the test set,which makes it impossible to establish a traditional dependency matrix for the system level.The second problem is that the system level fault detection rate and the fault isolation rate(referred to as"two rates")are not enough to describe the fault diagnostic ability of the system level tests.An innovative dependency matrix(called combinatorial dependency matrix)composed of three submatrices is presented.The first problem is solved by simplifying the submatrix between the units’fault and the test,and the second problem is solved by establishing the system level fault detection rate,the fault isolation rate and the integrated fault detection rate(referred to as"three rates")based on the new matrix.The mathematical model of the system level test selection problem is constructed,and the binary genetic algorithm is applied to solve the problem,which achieves the goal of system level test selection.展开更多
文摘Over the past years,many efforts have been accomplished to achieve fast and accurate meta-heuristic algorithms to optimize a variety of real-world problems.This study presents a new optimization method based on an unusual geological phenomenon in nature,named Geyser inspired Algorithm(GEA).The mathematical modeling of this geological phenomenon is carried out to have a better understanding of the optimization process.The efficiency and accuracy of GEA are verified using statistical examination and convergence rate comparison on numerous CEC 2005,CEC 2014,CEC 2017,and real-parameter benchmark functions.Moreover,GEA has been applied to several real-parameter engineering optimization problems to evaluate its effectiveness.In addition,to demonstrate the applicability and robustness of GEA,a comprehensive investigation is performed for a fair comparison with other standard optimization methods.The results demonstrate that GEA is noticeably prosperous in reaching the optimal solutions with a high convergence rate in comparison with other well-known nature-inspired algorithms,including ABC,BBO,PSO,and RCGA.Note that the source code of the GEA is publicly available at https://www.optim-app.com/projects/gea.
基金Supported by the Agencia Nacional de Producción Científica y Tecnológica(ANPCyT),No.ANR BIO 0032/10
文摘The reconstitution of a fully organized and functional hair follicle from dissociated cells propagated under defined tissue culture conditions is a challenge stillpending in tissue engineering. The loss of hair follicles caused by injuries or pathologies such as alopecia not only affects the patients' psychological well-being, but also endangers certain inherent functions of the skin. It is then of great interest to find different strategies aiming to regenerate or neogenerate the hair follicle under conditions proper of an adult individual. Based upon current knowledge on the epithelial and dermal cells and their interactions during the embryonic hair generation and adult hair cycling, many researchers have tried to obtain mature hair follicles using different strategies and approaches depending on the causes of hair loss. This review summarizes current advances in the different experimental strategies to regenerate or neogenerate hair follicles, with emphasis on those involving neogenesis of hair follicles in adult individuals using isolated cells and tissue engineering. Most of these experiments were performed using rodent cells, particularly from embryonic or newborn origin. However, no successful strategy to generate human hair follicles from adult cells has yet been reported. This review identifies several issues that should be considered to achieve this objective. Perhaps the most important challenge is to provide threedimensional culture conditions mimicking the structure of living tissue. Improving culture conditions that allow the expansion of specific cells while protecting their inductive properties, as well as methods for selecting populations of epithelial stem cells, should give us the necessary tools to overcome the difficulties that constrain human hair follicle neogenesis. An analysis of patent trends shows that the number of patent applications aimed at hair follicle regeneration and neogenesis has been increasing during the last decade. This field is attractive not only to academic researchers
基金supported by the National Natural Science Foundation of China(82293651)the CAMS Innovation Fund for Medical Sciences(2019-I2M-5-055)the Guangdong Provincial Key Laboratory of Brain Connectome and Behavior(2017B030301017).
文摘1.The need to develop a holographic digital mannequin Life processes,including high intelligence,self-organization,and homeostasis,are characterized by the biological organism in the form of self-renewal,self-replication and self-regulation,metabolism,self-repair,and self-reproduction,which are all processes of multisystem coordinated movement[1].Research in the field of life sciences is not limited to the use of advanced observational methods to reveal microscopic structures at the subcellular or molecular level.Discoveries based on these methods alone cannot characterize the dynamic processes of life at the microscopic and molecular level[2].
基金funded by Princess Nourah bint Abdulrahman University Researchers Supporting Project Number(PNURSP2024R435),Princess Nourah bint Abdulrahman University,Riyadh,Saudi Arabia.
文摘Heart disease remains a leading cause of morbidity and mortality worldwide,highlighting the need for improved diagnostic methods.Traditional diagnostics face limitations such as reliance on single-modality data and vulnerability to apparatus faults,which can reduce accuracy,especially with poor-quality images.Additionally,these methods often require significant time and expertise,making them less accessible in resource-limited settings.Emerging technologies like artificial intelligence and machine learning offer promising solutions by integrating multi-modality data and enhancing diagnostic precision,ultimately improving patient outcomes and reducing healthcare costs.This study introduces Heart-Net,a multi-modal deep learning framework designed to enhance heart disease diagnosis by integrating data from Cardiac Magnetic Resonance Imaging(MRI)and Electrocardiogram(ECG).Heart-Net uses a 3D U-Net for MRI analysis and a Temporal Convolutional Graph Neural Network(TCGN)for ECG feature extraction,combining these through an attention mechanism to emphasize relevant features.Classification is performed using Optimized TCGN.This approach improves early detection,reduces diagnostic errors,and supports personalized risk assessments and continuous health monitoring.The proposed approach results show that Heart-Net significantly outperforms traditional single-modality models,achieving accuracies of 92.56%forHeartnetDataset Ⅰ(HNET-DSⅠ),93.45%forHeartnetDataset Ⅱ(HNET-DSⅡ),and 91.89%for Heartnet Dataset Ⅲ(HNET-DSⅢ),mitigating the impact of apparatus faults and image quality issues.These findings underscore the potential of Heart-Net to revolutionize heart disease diagnostics and improve clinical outcomes.
基金funded by Princess Nourah bint Abdulrahman University Researchers Supporting Project number(PNURSP2024R435),Princess Nourah bint Abdulrahman University,Riyadh,Saudi Arabia.
文摘The article describes a new method for malware classification,based on a Machine Learning(ML)model architecture specifically designed for malware detection,enabling real-time and accurate malware identification.Using an innovative feature dimensionality reduction technique called the Interpolation-based Feature Dimensionality Reduction Technique(IFDRT),the authors have significantly reduced the feature space while retaining critical information necessary for malware classification.This technique optimizes the model’s performance and reduces computational requirements.The proposed method is demonstrated by applying it to the BODMAS malware dataset,which contains 57,293 malware samples and 77,142 benign samples,each with a 2381-feature vector.Through the IFDRT method,the dataset is transformed,reducing the number of features while maintaining essential data for accurate classification.The evaluation results show outstanding performance,with an F1 score of 0.984 and a high accuracy of 98.5%using only two reduced features.This demonstrates the method’s ability to classify malware samples accurately while minimizing processing time.The method allows for improving computational efficiency by reducing the feature space,which decreases the memory and time requirements for training and prediction.The new method’s effectiveness is confirmed by the calculations,which indicate significant improvements in malware classification accuracy and efficiency.The research results enhance existing malware detection techniques and can be applied in various cybersecurity applications,including real-timemalware detection on resource-constrained devices.Novelty and scientific contribution lie in the development of the IFDRT method,which provides a robust and efficient solution for feature reduction in ML-based malware classification,paving the way for more effective and scalable cybersecurity measures.
基金The authors extend their appreciation to the Deanship of Scientific Research at King Khalid University for funding this work through the small Groups Project under grant number(168/43)Princess Nourah bint Abdulrahman University Researchers Supporting Project number(PNURSP2022R151),Princess Nourah bint Abdulrahman University,Riyadh,Saudi ArabiaThe authors would like to thank the Deanship of Scientific Research at Umm Al-Qura University for supporting this work by Grant Code:(22UQU4310373DSR59).
文摘Emerging technologies such as edge computing,Internet of Things(IoT),5G networks,big data,Artificial Intelligence(AI),and Unmanned Aerial Vehicles(UAVs)empower,Industry 4.0,with a progressive production methodology that shows attention to the interaction between machine and human beings.In the literature,various authors have focused on resolving security problems in UAV communication to provide safety for vital applications.The current research article presents a Circle Search Optimization with Deep Learning Enabled Secure UAV Classification(CSODL-SUAVC)model for Industry 4.0 environment.The suggested CSODL-SUAVC methodology is aimed at accomplishing two core objectives such as secure communication via image steganography and image classification.Primarily,the proposed CSODL-SUAVC method involves the following methods such as Multi-Level Discrete Wavelet Transformation(ML-DWT),CSO-related Optimal Pixel Selection(CSO-OPS),and signcryption-based encryption.The proposed model deploys the CSO-OPS technique to select the optimal pixel points in cover images.The secret images,encrypted by signcryption technique,are embedded into cover images.Besides,the image classification process includes three components namely,Super-Resolution using Convolution Neural Network(SRCNN),Adam optimizer,and softmax classifier.The integration of the CSO-OPS algorithm and Adam optimizer helps in achieving the maximum performance upon UAV communication.The proposed CSODLSUAVC model was experimentally validated using benchmark datasets and the outcomes were evaluated under distinct aspects.The simulation outcomes established the supreme better performance of the CSODL-SUAVC model over recent approaches.
基金the Deanship of Scientific Research at King Khalid University for funding this work through Large Groups Project under grant number(61/43)Princess Nourah bint Abdulrahman University Researchers Supporting Project number(PNURSP2022R319)Princess Nourah bint Abdulrahman University,Riyadh,Saudi Arabia.The authors would like to thank the Deanship of Scientific Research at Umm Al-Qura University for supporting this work by Grant Code:(22UQU4340237DSR27).
文摘Nowadays,Internet of Things(IoT)has penetrated all facets of human life while on the other hand,IoT devices are heavily prone to cyberattacks.It has become important to develop an accurate system that can detect malicious attacks on IoT environments in order to mitigate security risks.Botnet is one of the dreadfulmalicious entities that has affected many users for the past few decades.It is challenging to recognize Botnet since it has excellent carrying and hidden capacities.Various approaches have been employed to identify the source of Botnet at earlier stages.Machine Learning(ML)and Deep Learning(DL)techniques are developed based on heavy influence from Botnet detection methodology.In spite of this,it is still a challenging task to detect Botnet at early stages due to low number of features accessible from Botnet dataset.The current study devises IoT with Cloud Assisted Botnet Detection and Classification utilizingRat SwarmOptimizer with Deep Learning(BDC-RSODL)model.The presented BDC-RSODL model includes a series of processes like pre-processing,feature subset selection,classification,and parameter tuning.Initially,the network data is pre-processed to make it compatible for further processing.Besides,RSO algorithm is exploited for effective selection of subset of features.Additionally,Long Short TermMemory(LSTM)algorithm is utilized for both identification and classification of botnets.Finally,Sine Cosine Algorithm(SCA)is executed for fine-tuning the hyperparameters related to LSTM model.In order to validate the promising 3086 CMC,2023,vol.74,no.2 performance of BDC-RSODL system,a comprehensive comparison analysis was conducted.The obtained results confirmed the supremacy of BDCRSODL model over recent approaches.
基金the Deanship of Scientific Research(DSR),King Abdulaziz University,Jeddah,under grant No.(FP-000-000-1441).
文摘Colorectal carcinoma(CRC)is one such dispersed cancer globally and also prominent one in causing cancer-based death.Conventionally,pathologists execute CRC diagnosis through visible scrutinizing under the microscope the resected tissue samples,stained and fixed through Haematoxylin and Eosin(H&E).The advancement of graphical processing systems has resulted in high potentiality for deep learning(DL)techniques in interpretating visual anatomy from high resolution medical images.This study develops a slime mould algorithm with deep transfer learning enabled colorectal cancer detection and classification(SMADTL-CCDC)algorithm.The presented SMADTL-CCDC technique intends to appropriately recognize the occurrence of colorectal cancer.To accomplish this,the SMADTLCCDC model initially undergoes pre-processing to improve the input image quality.In addition,a dense-EfficientNet technique was employed to extract feature vectors from the pre-processed images.Moreover,SMA with Discrete Hopfield neural network(DHNN)method was applied for the recognition and classification of colorectal cancer.The utilization of SMA assists in appropriately selecting the parameters involved in the DHNN approach.A wide range of experiments was implemented on benchmark datasets to assess the classification performance.A comprehensive comparative study highlighted the better performance of the SMADTL-CDC model over the recent approaches.
基金The Deanship of Scientific Research(DSR)at King Abdulaziz University,Jeddah,Saudi Arabia has funded this project,under grant no.(FP-206-43).
文摘Liver cancer is one of the major diseases with increased mortality in recent years,across the globe.Manual detection of liver cancer is a tedious and laborious task due to which Computer Aided Diagnosis(CAD)models have been developed to detect the presence of liver cancer accurately and classify its stages.Besides,liver cancer segmentation outcome,using medical images,is employed in the assessment of tumor volume,further treatment plans,and response moni-toring.Hence,there is a need exists to develop automated tools for liver cancer detection in a precise manner.With this motivation,the current study introduces an Intelligent Artificial Intelligence with Equilibrium Optimizer based Liver cancer Classification(IAIEO-LCC)model.The proposed IAIEO-LCC technique initially performs Median Filtering(MF)-based pre-processing and data augmentation process.Besides,Kapur’s entropy-based segmentation technique is used to identify the affected regions in liver.Moreover,VGG-19 based feature extractor and Equilibrium Optimizer(EO)-based hyperparameter tuning processes are also involved to derive the feature vectors.At last,Stacked Gated Recurrent Unit(SGRU)classifier is exploited to detect and classify the liver cancer effectively.In order to demonstrate the superiority of the proposed IAIEO-LCC technique in terms of performance,a wide range of simulations was conducted and the results were inspected under different measures.The comparison study results infer that the proposed IAIEO-LCC technique achieved an improved accuracy of 98.52%.
基金supported by the Young Scientists Fund of the National Natural Science Foundation of China(31500849)Shanghai Municipal Science and Technology Major Project(18JC1410100,2018SHZDZX05)+3 种基金the Key Research Program of Frontier Sciences(QYZDY-SSW-SMC028)the Strategic Priority Research Program(XDB32010200)of Chinese Academy of Sciencesthe International Partnership Program,Bureau of International Co-operation of Chinese Academy of Sciences(153D31KYSB20170059)China Wan-Ren Program,and Shanghai Leading Scientist Program
文摘The zebrafish has become a popular vertebrate animal model in biomedical research.However,it is still challenging to make conditional gene knockout(CKO)models in zebrafish due to the low efficiency of homologous recombination(HR).Here we report an efficient non-HR-based method for generating zebrafish carrying a CKO and knockin(KI)switch(zCKOIS)coupled with dual-color fluorescent reporters.Using this strategy,we generated hey2^zCKOIS which served as a hey2 KI reporter with EGFP expression.Upon Cre induction in targeted cells,the hey2^zCKOIS was switched to a non-functional CKO allele hey2^zCKOIS-inv associated with Tag RFP expression,enabling visualization of the CKO alleles.Thus,simplification of the design,and the visibility and combination of both CKO and KI alleles make our z CKOIS strategy an applicable CKO approach for zebrafish.
基金This research work was funded by Institution Fund projects under Grant No.(IFPRC-215-249-2020)Therefore,authors gratefully acknowledge technical and financial support from the Ministry of Education and King Abdulaziz University,DSR,Jeddah,Saudi Arabia.
文摘Rapid advancements of the Industrial Internet of Things(IIoT)and artificial intelligence(AI)pose serious security issues by revealing secret data.Therefore,security data becomes a crucial issue in IIoT communication where secrecy needs to be guaranteed in real time.Practically,AI techniques can be utilized to design image steganographic techniques in IIoT.In addition,encryption techniques act as an important role to save the actual information generated from the IIoT devices to avoid unauthorized access.In order to accomplish secure data transmission in IIoT environment,this study presents novel encryption with image steganography based data hiding technique(EISDHT)for IIoT environment.The proposed EIS-DHT technique involves a new quantum black widow optimization(QBWO)to competently choose the pixel values for hiding secrete data in the cover image.In addition,the multi-level discrete wavelet transform(DWT)based transformation process takes place.Besides,the secret image is divided into three R,G,and B bands which are then individually encrypted using Blowfish,Twofish,and Lorenz Hyperchaotic System.At last,the stego image gets generated by placing the encrypted images into the optimum pixel locations of the cover image.In order to validate the enhanced data hiding performance of the EIS-DHT technique,a set of simulation analyses take place and the results are inspected interms of different measures.The experimental outcomes stated the supremacy of the EIS-DHT technique over the other existing techniques and ensure maximum security.
基金supported by the National Natural Science Foundation of China(51605482)the Equipment Pre-research Project(41403020101).
文摘Test selection is to select the test set with the least total cost or the least total number from the alternative test set on the premise of meeting the required testability indicators.The existing models and methods are not suitable for system level test selection.The first problem is the lack of detailed data of the units’fault set and the test set,which makes it impossible to establish a traditional dependency matrix for the system level.The second problem is that the system level fault detection rate and the fault isolation rate(referred to as"two rates")are not enough to describe the fault diagnostic ability of the system level tests.An innovative dependency matrix(called combinatorial dependency matrix)composed of three submatrices is presented.The first problem is solved by simplifying the submatrix between the units’fault and the test,and the second problem is solved by establishing the system level fault detection rate,the fault isolation rate and the integrated fault detection rate(referred to as"three rates")based on the new matrix.The mathematical model of the system level test selection problem is constructed,and the binary genetic algorithm is applied to solve the problem,which achieves the goal of system level test selection.
