Uterine natural killer(uNK)cells,sharing many characters with peripheral blood natural killer(pNK)cells,are a major uterine lymphocyte population at early gestational stages during normal pregnancy in placental mammal...Uterine natural killer(uNK)cells,sharing many characters with peripheral blood natural killer(pNK)cells,are a major uterine lymphocyte population at early gestational stages during normal pregnancy in placental mammals. The functions of uNK cells include cytokine production and cytotoxcity that are regulated by signals through activating and inhibitory receptors.UNK cells differ from pNK cells however and contribute to the structural changes that accompany the differentiation of the maternal-fetal interface.Immunological mechanisms must provide a balanced environment for uNK cell proliferation,differentiation and activation through intricate signaling pathways.An improved knowledge of mechanisms regulating uNK cells development and the cytokine network at the maternal-fetal interface of mice and humans might be useful to harness the power of these cells for maintenance of pregnancy.Cellular & Molecular Immunology.2005;2(2):123-129.展开更多
Definition of a new geologic period for the Iast interval of the Proterozoic Eon, the Ediacaran, was recently ratified by the IUGS. The Ediacaran Period is the first Proterozoic period to be recognized on the basis of...Definition of a new geologic period for the Iast interval of the Proterozoic Eon, the Ediacaran, was recently ratified by the IUGS. The Ediacaran Period is the first Proterozoic period to be recognized on the basis of chronostratigraphic criteria, the first internationally ratified, chronostratigraphically defined period of any age to be introduced in more than 120 years, and the first to be defined by a “golden spike” in the Southern hemisphere.展开更多
In an earlier paper we showed that symmetry breaking could be induced in the triiodide ion by varying the solvent. Experiments and simulations suggest that protic solvents which can form hydrogen bonds with a negative...In an earlier paper we showed that symmetry breaking could be induced in the triiodide ion by varying the solvent. Experiments and simulations suggest that protic solvents which can form hydrogen bonds with a negative ion cause symmetry breaking of the ion, so that the charge becomes concentrated at one end of the ion and the corresponding bond elongates. We suggested that one could draw an analogy between the mean field Ising model with free energy,展开更多
文摘Uterine natural killer(uNK)cells,sharing many characters with peripheral blood natural killer(pNK)cells,are a major uterine lymphocyte population at early gestational stages during normal pregnancy in placental mammals. The functions of uNK cells include cytokine production and cytotoxcity that are regulated by signals through activating and inhibitory receptors.UNK cells differ from pNK cells however and contribute to the structural changes that accompany the differentiation of the maternal-fetal interface.Immunological mechanisms must provide a balanced environment for uNK cell proliferation,differentiation and activation through intricate signaling pathways.An improved knowledge of mechanisms regulating uNK cells development and the cytokine network at the maternal-fetal interface of mice and humans might be useful to harness the power of these cells for maintenance of pregnancy.Cellular & Molecular Immunology.2005;2(2):123-129.
文摘Definition of a new geologic period for the Iast interval of the Proterozoic Eon, the Ediacaran, was recently ratified by the IUGS. The Ediacaran Period is the first Proterozoic period to be recognized on the basis of chronostratigraphic criteria, the first internationally ratified, chronostratigraphically defined period of any age to be introduced in more than 120 years, and the first to be defined by a “golden spike” in the Southern hemisphere.
文摘In an earlier paper we showed that symmetry breaking could be induced in the triiodide ion by varying the solvent. Experiments and simulations suggest that protic solvents which can form hydrogen bonds with a negative ion cause symmetry breaking of the ion, so that the charge becomes concentrated at one end of the ion and the corresponding bond elongates. We suggested that one could draw an analogy between the mean field Ising model with free energy,