Dihadron azimuthal correlations containing a high transverse momentum(pr)trigger particle are sensit-ive to the properties of the nuclear medium created at RHIC through the strong interactions occurring between the tr...Dihadron azimuthal correlations containing a high transverse momentum(pr)trigger particle are sensit-ive to the properties of the nuclear medium created at RHIC through the strong interactions occurring between the traversing parton and the medium,ie.jet-quenching.Previous measurements revealed a strong modification to di-hadron azimuthal correlations in Au+Au collisions with respect to ptp and d+Au collisions.The modification in-creases with the collision centrality,suggesting a path-length or energy density dependence to the je-quenching ef-fect.This paper reports STAR measurements of dihadron azimuthal correlations in mid-central(20%-60%)Au+Au collisions at√^(S)NN=200 GeV as a function of the trigger particle's azimuthal angle relative to the event plane,Ф_(s)=|Ф_(t)-ψ_(Ep)|.The azimuthal correlation is studied as a function of both the trigger and associated particle pr.The subtractions of the combinatorial background and anisotropic flow,assuming Zero Yield At Minimum(ZYAM),are described.The correlation results are first discussed with subtraction of the even harmonic(elliptic and quadrangu-lar)flow backgrounds.The away-side correlation is strongly modifed,and the modification varies withФ_(s),with a double-peak structure for out-of-plane trigger particles.The near-side ridge(long range pseudo-rapidity△_(η)correla-tion)appears to drop with increasingФ_(s)while the jet-like component remains approximately constant.The correla-tion functions are further studied with the subtraction of odd harmonic triangular flow background arising from fluc-tuations.It is found that the triangular flow,while responsible for the majority of the amplitudes,is not sufficient to explain theφs-dependence of the ridge or the away-side double-peak structure.The dropping ridge withФ_(s)could be attributed to aФ_(s)-dependent lliptie anisotropy;however,the physics mechanism of the ridge remains an open ques-tion.Even with aФ_(s)-dependent elliptic flow,the away-side correlation structure is robust.These results,with exte展开更多
BACKGROUND:The present study aimed to explore the relationship between surgical methods,hemorrhage position,hemorrhage volume,surgical timing and treatment outcome of hypertensive intracerebral hemorrhage(HICH).METHOD...BACKGROUND:The present study aimed to explore the relationship between surgical methods,hemorrhage position,hemorrhage volume,surgical timing and treatment outcome of hypertensive intracerebral hemorrhage(HICH).METHODS:A total of 1 310 patients,who had been admitted to six hospitals from January 2004 to January 2008,were divided into six groups according to different surgical methods:craniotomy through bone fl ap(group A),craniotomy through a small bone window(group B),stereotactic drilling drainage(group C1 and group C2),neuron-endoscopy operation(group D) and external ventricular drainage(group E) in consideration of hemorrhage position,hemorrhage volume and clinical practice. A retrospective analysis was made of surgical timing and curative effect of the surgical methods.RESULTS:The effectiveness rate of the methods was 74.12% for 1 310 patients after onemonth follow-up. In this series,the disability rate was 44.82% 3–6 months after the operation. Among the 1 310 patients,241(18.40%) patients died after the operation. If hematoma volume was >80 mL and the operation was performed within 3 hours,the mortality rate of group A was signifi cantly lower than that of groups B,C,D,and E(P<0.05). If hematoma volume was 50–80 mL and the operation was performed within 6–12 hours,the mortality rate of groups B and D was lower than that of groups A,C and E(P<0.05). If hematoma volume was 20–50 mL and the operation was performed within 6–24 hours,the mortality rate of group C was lower than that of groups A,B and D(P<0.05).CONCLUSIONS:Craniotomy through a bone f lap is suitable for patients with a large hematoma and hernia of the brain. Stereotactic drilling drainage is suggested for patients with hematoma volume less than 80 mL. The curative effect of HICH individualized treatment would be improved via the suitable selection of operation time and surgical method according to the position and volume of hemorrhage.展开更多
We present a method for solving partial differential equations using artificial neural networks and an adaptive collocation strategy.In this procedure,a coarse grid of training points is used at the initial training s...We present a method for solving partial differential equations using artificial neural networks and an adaptive collocation strategy.In this procedure,a coarse grid of training points is used at the initial training stages,while more points are added at later stages based on the value of the residual at a larger set of evaluation points.This method increases the robustness of the neural network approximation and can result in significant computational savings,particularly when the solution is non-smooth.Numerical results are presented for benchmark problems for scalar-valued PDEs,namely Poisson and Helmholtz equations,as well as for an inverse acoustics problem.展开更多
The Chinese Tianshan belt is a major part of the southern Central Asian Orogenic Belt, extending westward to Kyrgyzstan and Kazakhstan. Its Paleozoic tectonic evolution, crucial for understanding the amalgamation of C...The Chinese Tianshan belt is a major part of the southern Central Asian Orogenic Belt, extending westward to Kyrgyzstan and Kazakhstan. Its Paleozoic tectonic evolution, crucial for understanding the amalgamation of Central Asia, comprises two stages of subduction-collision. The first collisional stage built the Eo-Tianshan Mountains, before a Visean unconformity, in which all structures are verging north. It implied a southward subduction of the Central Tianshan Ocean beneath the Tarim active margin, that induced the Ordovician-Early Devonian Central Tianshan arc, to the south of which the South Tianshan back-arc basin opened. During the Late Devonian, the closure of this ocean led to a collision between Central Tianshan arc and the Kazakhstan-Yili-North Tianshan Block, and subsequently closure of the South Tianhan back-arc basin, producing two suture zones, namely the Central Tianshan and South Tianshan suture zones where ophiolitic melanges and HP metamorphic rocks were emplaced northward. The second stage included the Late Devonian-Carboniferous southward subduction of North Tianshan Ocean beneath the Eo-Tianshan active margin, underlined by the Yili-North Tianshan arc, leading to the collision between the Kazakhstan-Yili-NTS plate and an inferred Junggar Block at Late Carboniferous-Early Permian time. The North Tianshan Suture Zone underlines likely the last oceanic closure of Central Asia Orogenic Belt; all the oceanic domains were consumed before the Middle Permian. The amalgamated units were affected by a Permian major wrenching, dextral in the Tianshan. The correlation with the Kazakh and Kyrgyz Tianshan is clarified. The Kyrgyz South Tianshan is equivalent to the whole part of Chinese Tianshan (CTS and STS) located to the south of Narat Fault and Main Tianshan Shear Zone; the so-called Middle Tianshan thins out toward the east. The South Tianshan Suture of Kyrgyzstan correlates with the Central Tianshan Suture of Chinese Tianshan. The evolution of this southern domain remains similar from east (Ga展开更多
High-entropy ceramics (HECs) are solid solutions of inorganic compounds with one or more Wyckoff sites shared by equal or near-equal atomic ratios of multi-principal elements.Although in the infant stage,the emerging ...High-entropy ceramics (HECs) are solid solutions of inorganic compounds with one or more Wyckoff sites shared by equal or near-equal atomic ratios of multi-principal elements.Although in the infant stage,the emerging of this new family of materials has brought new opportunities for material design and property tailoring.Distinct from metals,the diversity in crystal structure and electronic structure of ceramics provides huge space for properties tuning through band structure engineering and phonon engineering.Aside from strengthening,hardening,and low thermal conductivity that have already been found in high-entropy alloys,new properties like colossal dielectric constant,super ionic conductivity,severe anisotropic thermal expansion coefficient,strong electromagnetic wave absorption,etc.,have been discovered in HECs.As a response to the rapid development in this nascent field,this article gives a comprehensive review on the structure features,theoretical methods for stability and property prediction,processing routes,novel properties,and prospective applications of HECs.The challenges on processing,characterization,and property predictions are also emphasized.Finally,future directions for new material exploration,novel processing,fundamental understanding,in-depth characterization,and database assessments are given.展开更多
Acute pancreatitis (AP) is a rare event in pregnancy, occurring in approximately 3 in 10 000 pregnancies. The spectrum of AP in pregnancy ranges from mild pancreatitis to serious pancreatitis associated with necrosis,...Acute pancreatitis (AP) is a rare event in pregnancy, occurring in approximately 3 in 10 000 pregnancies. The spectrum of AP in pregnancy ranges from mild pancreatitis to serious pancreatitis associated with necrosis, abscesses, pseudocysts and multiple organ dysfunction syndromes. Pregnancy related hematological and biochemical alterations infl uence the interpretation of diagnostic tests and assessment of severity of AP. As in any other disease associated with pregnancy, AP is associated with greater concerns as it deals with two lives rather than just one as in the non-pregnant population. The recent advances in clinical gastroenterology have improved the early diagnosis and effective management of biliary pancreatitis. Diagnostic studies such as endoscopic ultrasound, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography and therapeutic modalities that include endoscopic sphincterotomy, biliary stenting, common bile duct stone extraction and laparoscopic cholecystectomy are major milestones in gastroenterology. When properly managed AP in pregnancy does not carry a dismal prognosis as in the past.展开更多
Portable electronic devices(PEDs)are promising information-exchange platforms for real-time responses.Their performance is becoming more and more sensitive to energy consumption.Rechargeable batteries are the primary ...Portable electronic devices(PEDs)are promising information-exchange platforms for real-time responses.Their performance is becoming more and more sensitive to energy consumption.Rechargeable batteries are the primary energy source of PEDs and hold the key to guarantee their desired performance stability.With the remarkable progress in battery technologies,multifunctional PEDs have constantly been emerging to meet the requests of our daily life conveniently.The ongoing surge in demand for high-performance PEDs inspires the relentless pursuit of even more powerful rechargeable battery systems in turn.In this review,we present how battery technologies contribute to the fast rise of PEDs in the last decades.First,a comprehensive overview of historical advances in PEDs is outlined.Next,four types of representative rechargeable batteries and their impacts on the practical development of PEDs are described comprehensively.The development trends toward a new generation of batteries and the future research focuses are also presented.展开更多
Importance:While laparoscopic pancreaticoduodenectomy(LPD)is being adopted with increasing enthusiasm worldwide,it is still challenging for both technical and anatomical reasons.Currently,there is no consensus on the ...Importance:While laparoscopic pancreaticoduodenectomy(LPD)is being adopted with increasing enthusiasm worldwide,it is still challenging for both technical and anatomical reasons.Currently,there is no consensus on the technical standards for LPD.Objective:The aim of this consensus statement is to guide the continued safe progression and adoption of LPD.Evidence Review:An international panel of experts was selected based on their clinical and scientific expertise in laparoscopic and open pancreaticoduodenectomy.Statements were produced upon reviewing the literature and assessed by the members of the expert panel.The literature search and its critical appraisal were limited to articles published in English during the period from 1994 to 2019.The Web of Science,Medline,and Cochrane Library and Clinical Trials databases were searched,The search strategy included,but was not limited to,the terms'laparoscopic','pancreaticoduodenectomy,'pancreatoduodenectomy','Whipple's operation',and'minimally invasive surgery'.Reference lists from the included articles were manually checked for any additional studies,which were included when appropriate.Delphi method was used to establish expert consensus and the AGREE II-GRS Instrument was applied to assess the methodological quality and externally validate the final statements.The statements were further discussed during a one-day face-to-face meeting at the 1st Summit on Minimally Invasive Pancreatico-Biliary Surgery in Wuhan,China.Findings:Twenty-eight international experts from 8 countries constructed the expert panel.Sixteen statements were produced by the members of the expert panel.At least 80%of responders agreed with the majority(80%)of statements.Other than three randomized controlled trials published to date,most evidences were based on level 3 or 4 studies according to the AGREE II-GRS Instrument.Conclusions and Relevance:The Wuhan international expert consensus meeting on LPD has produced a set of clinical practice statements for the safe development and progression of LP展开更多
Nasopharyngeal carcinoma(NPC)is a malignant epithelial tumor originating in the nasopharynx and has a high incidence in Southeast Asia and North Africa.To develop these comprehensive guidelines for the diagnosis and m...Nasopharyngeal carcinoma(NPC)is a malignant epithelial tumor originating in the nasopharynx and has a high incidence in Southeast Asia and North Africa.To develop these comprehensive guidelines for the diagnosis and management of NPC,the Chinese Society of Clinical Oncology(CSCO)arranged a multi-disciplinary team comprising of experts from all sub-specialties of NPC to write,discuss,and revise the guidelines.Based on the findings of evidencebased medicine in China and abroad,domestic experts have iteratively developed these guidelines to provide proper management of NPC.Overall,the guidelines describe the screening,clinical and pathological diagnosis,staging and risk assessment,therapies,and follow-up of NPC,which aim to improve the management of NPC.展开更多
Detecting and segmenting salient objects from natural scenes, often referred to as salient object detection, has attracted great interest in computer vision. While many models have been proposed and several applicatio...Detecting and segmenting salient objects from natural scenes, often referred to as salient object detection, has attracted great interest in computer vision. While many models have been proposed and several applications have emerged, a deep understanding of achievements and issues remains lacking. We aim to provide a comprehensive review of recent progress in salient object detection and situate this field among other closely related areas such as generic scene segmentation, object proposal generation, and saliency for fixation prediction. Covering 228 publications, we survey i) roots, key concepts, and tasks, ii) core techniques and main modeling trends, and iii) datasets and evaluation metrics for salient object detection. We also discuss open problems such as evaluation metrics and dataset bias in model performance, and suggest future research directions.展开更多
基金Supported in part by the Offices of NP and HEP within the U.S.DOE Office of Sciencethe U.S.NSF+18 种基金the Sloan Foundationthe DFG cluster of excellence‘Origin and Structure of the Universe’of Germany,CNRS/IN2P3STFC and EPSRC of the United KingdomFAPESP CNPq of Brazil,Ministry of Ed.Sci.of the Russian FederationNNSFCCASMoSTMoE of ChinaGA and MSMT of the Czech RepublicFOM and NWO of the NetherlandsDAEDSTCSIR of IndiaPolish Ministry of Sci.Higher Ed.,Korea Research Foundation,Ministry of Sci.,Ed.Sports of the Rep.Of CroatiaRussian Ministry of Sci.and TechRos-Atom of Russia。
文摘Dihadron azimuthal correlations containing a high transverse momentum(pr)trigger particle are sensit-ive to the properties of the nuclear medium created at RHIC through the strong interactions occurring between the traversing parton and the medium,ie.jet-quenching.Previous measurements revealed a strong modification to di-hadron azimuthal correlations in Au+Au collisions with respect to ptp and d+Au collisions.The modification in-creases with the collision centrality,suggesting a path-length or energy density dependence to the je-quenching ef-fect.This paper reports STAR measurements of dihadron azimuthal correlations in mid-central(20%-60%)Au+Au collisions at√^(S)NN=200 GeV as a function of the trigger particle's azimuthal angle relative to the event plane,Ф_(s)=|Ф_(t)-ψ_(Ep)|.The azimuthal correlation is studied as a function of both the trigger and associated particle pr.The subtractions of the combinatorial background and anisotropic flow,assuming Zero Yield At Minimum(ZYAM),are described.The correlation results are first discussed with subtraction of the even harmonic(elliptic and quadrangu-lar)flow backgrounds.The away-side correlation is strongly modifed,and the modification varies withФ_(s),with a double-peak structure for out-of-plane trigger particles.The near-side ridge(long range pseudo-rapidity△_(η)correla-tion)appears to drop with increasingФ_(s)while the jet-like component remains approximately constant.The correla-tion functions are further studied with the subtraction of odd harmonic triangular flow background arising from fluc-tuations.It is found that the triangular flow,while responsible for the majority of the amplitudes,is not sufficient to explain theφs-dependence of the ridge or the away-side double-peak structure.The dropping ridge withФ_(s)could be attributed to aФ_(s)-dependent lliptie anisotropy;however,the physics mechanism of the ridge remains an open ques-tion.Even with aФ_(s)-dependent elliptic flow,the away-side correlation structure is robust.These results,with exte
基金supported by a grant from Shanghai Pudong New Area(PWZxkq2011-01)
文摘BACKGROUND:The present study aimed to explore the relationship between surgical methods,hemorrhage position,hemorrhage volume,surgical timing and treatment outcome of hypertensive intracerebral hemorrhage(HICH).METHODS:A total of 1 310 patients,who had been admitted to six hospitals from January 2004 to January 2008,were divided into six groups according to different surgical methods:craniotomy through bone fl ap(group A),craniotomy through a small bone window(group B),stereotactic drilling drainage(group C1 and group C2),neuron-endoscopy operation(group D) and external ventricular drainage(group E) in consideration of hemorrhage position,hemorrhage volume and clinical practice. A retrospective analysis was made of surgical timing and curative effect of the surgical methods.RESULTS:The effectiveness rate of the methods was 74.12% for 1 310 patients after onemonth follow-up. In this series,the disability rate was 44.82% 3–6 months after the operation. Among the 1 310 patients,241(18.40%) patients died after the operation. If hematoma volume was >80 mL and the operation was performed within 3 hours,the mortality rate of group A was signifi cantly lower than that of groups B,C,D,and E(P<0.05). If hematoma volume was 50–80 mL and the operation was performed within 6–12 hours,the mortality rate of groups B and D was lower than that of groups A,C and E(P<0.05). If hematoma volume was 20–50 mL and the operation was performed within 6–24 hours,the mortality rate of group C was lower than that of groups A,B and D(P<0.05).CONCLUSIONS:Craniotomy through a bone f lap is suitable for patients with a large hematoma and hernia of the brain. Stereotactic drilling drainage is suggested for patients with hematoma volume less than 80 mL. The curative effect of HICH individualized treatment would be improved via the suitable selection of operation time and surgical method according to the position and volume of hemorrhage.
文摘We present a method for solving partial differential equations using artificial neural networks and an adaptive collocation strategy.In this procedure,a coarse grid of training points is used at the initial training stages,while more points are added at later stages based on the value of the residual at a larger set of evaluation points.This method increases the robustness of the neural network approximation and can result in significant computational savings,particularly when the solution is non-smooth.Numerical results are presented for benchmark problems for scalar-valued PDEs,namely Poisson and Helmholtz equations,as well as for an inverse acoustics problem.
基金supported by National Basic Research Program of China (Grant No. 2007CB411301)the Bureau of China Geological Survey (Grant No. 1212010611806)ISTO
文摘The Chinese Tianshan belt is a major part of the southern Central Asian Orogenic Belt, extending westward to Kyrgyzstan and Kazakhstan. Its Paleozoic tectonic evolution, crucial for understanding the amalgamation of Central Asia, comprises two stages of subduction-collision. The first collisional stage built the Eo-Tianshan Mountains, before a Visean unconformity, in which all structures are verging north. It implied a southward subduction of the Central Tianshan Ocean beneath the Tarim active margin, that induced the Ordovician-Early Devonian Central Tianshan arc, to the south of which the South Tianshan back-arc basin opened. During the Late Devonian, the closure of this ocean led to a collision between Central Tianshan arc and the Kazakhstan-Yili-North Tianshan Block, and subsequently closure of the South Tianhan back-arc basin, producing two suture zones, namely the Central Tianshan and South Tianshan suture zones where ophiolitic melanges and HP metamorphic rocks were emplaced northward. The second stage included the Late Devonian-Carboniferous southward subduction of North Tianshan Ocean beneath the Eo-Tianshan active margin, underlined by the Yili-North Tianshan arc, leading to the collision between the Kazakhstan-Yili-NTS plate and an inferred Junggar Block at Late Carboniferous-Early Permian time. The North Tianshan Suture Zone underlines likely the last oceanic closure of Central Asia Orogenic Belt; all the oceanic domains were consumed before the Middle Permian. The amalgamated units were affected by a Permian major wrenching, dextral in the Tianshan. The correlation with the Kazakh and Kyrgyz Tianshan is clarified. The Kyrgyz South Tianshan is equivalent to the whole part of Chinese Tianshan (CTS and STS) located to the south of Narat Fault and Main Tianshan Shear Zone; the so-called Middle Tianshan thins out toward the east. The South Tianshan Suture of Kyrgyzstan correlates with the Central Tianshan Suture of Chinese Tianshan. The evolution of this southern domain remains similar from east (Ga
基金Financial supports from the National Natural Science Foundation of China under Grant Nos.51972089,51672064,and U1435206 are also acknowledged.
文摘High-entropy ceramics (HECs) are solid solutions of inorganic compounds with one or more Wyckoff sites shared by equal or near-equal atomic ratios of multi-principal elements.Although in the infant stage,the emerging of this new family of materials has brought new opportunities for material design and property tailoring.Distinct from metals,the diversity in crystal structure and electronic structure of ceramics provides huge space for properties tuning through band structure engineering and phonon engineering.Aside from strengthening,hardening,and low thermal conductivity that have already been found in high-entropy alloys,new properties like colossal dielectric constant,super ionic conductivity,severe anisotropic thermal expansion coefficient,strong electromagnetic wave absorption,etc.,have been discovered in HECs.As a response to the rapid development in this nascent field,this article gives a comprehensive review on the structure features,theoretical methods for stability and property prediction,processing routes,novel properties,and prospective applications of HECs.The challenges on processing,characterization,and property predictions are also emphasized.Finally,future directions for new material exploration,novel processing,fundamental understanding,in-depth characterization,and database assessments are given.
文摘Acute pancreatitis (AP) is a rare event in pregnancy, occurring in approximately 3 in 10 000 pregnancies. The spectrum of AP in pregnancy ranges from mild pancreatitis to serious pancreatitis associated with necrosis, abscesses, pseudocysts and multiple organ dysfunction syndromes. Pregnancy related hematological and biochemical alterations infl uence the interpretation of diagnostic tests and assessment of severity of AP. As in any other disease associated with pregnancy, AP is associated with greater concerns as it deals with two lives rather than just one as in the non-pregnant population. The recent advances in clinical gastroenterology have improved the early diagnosis and effective management of biliary pancreatitis. Diagnostic studies such as endoscopic ultrasound, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography and therapeutic modalities that include endoscopic sphincterotomy, biliary stenting, common bile duct stone extraction and laparoscopic cholecystectomy are major milestones in gastroenterology. When properly managed AP in pregnancy does not carry a dismal prognosis as in the past.
基金This work was supported by National Key Research and Development Program(2016YFA0202500 and 2015CB932500)National Natural Science Foundation of China(21676160,51602107,21776019,21825501,21808124,and U1801257)+3 种基金the Tsinghua University Initiative Scientific Research Program,the China Postdoctoral Science Foundation(2017M620049)the Tip-top Scientific and Technical Innovative Youth Talents of Guangdong Special Support Program(2017TQ04C419)Y.Chen thanks funding support from Australian Research Council under the Future Fellowships scheme(FT160100107)Discovery Programme(DP180102210).
文摘Portable electronic devices(PEDs)are promising information-exchange platforms for real-time responses.Their performance is becoming more and more sensitive to energy consumption.Rechargeable batteries are the primary energy source of PEDs and hold the key to guarantee their desired performance stability.With the remarkable progress in battery technologies,multifunctional PEDs have constantly been emerging to meet the requests of our daily life conveniently.The ongoing surge in demand for high-performance PEDs inspires the relentless pursuit of even more powerful rechargeable battery systems in turn.In this review,we present how battery technologies contribute to the fast rise of PEDs in the last decades.First,a comprehensive overview of historical advances in PEDs is outlined.Next,four types of representative rechargeable batteries and their impacts on the practical development of PEDs are described comprehensively.The development trends toward a new generation of batteries and the future research focuses are also presented.
基金support ongoing meetings was provided by ISPOR-The Professional Society for Health Economics and Outcomes ResearchThe funders had no role in considering the study design or in the collection,analysis,interpretation of data,or writing of the report.Funding for DH and the Delphi Panel exercise was provided by 9363980 Canada Ine+1 种基金the NIHR Applied Research Collaboration(ARC)West Midlandsthe NIHR Health Protection Research Unit(HPRU)Gastrointestinal Infections,and the NIHR HPRU Genomics and Enabling data.
基金This study was supported by grants from The National Natural Science Foundation of China(81772950)Tongji Hospital Clinical Research Flagship Program(2019CR203)to RQ.
文摘Importance:While laparoscopic pancreaticoduodenectomy(LPD)is being adopted with increasing enthusiasm worldwide,it is still challenging for both technical and anatomical reasons.Currently,there is no consensus on the technical standards for LPD.Objective:The aim of this consensus statement is to guide the continued safe progression and adoption of LPD.Evidence Review:An international panel of experts was selected based on their clinical and scientific expertise in laparoscopic and open pancreaticoduodenectomy.Statements were produced upon reviewing the literature and assessed by the members of the expert panel.The literature search and its critical appraisal were limited to articles published in English during the period from 1994 to 2019.The Web of Science,Medline,and Cochrane Library and Clinical Trials databases were searched,The search strategy included,but was not limited to,the terms'laparoscopic','pancreaticoduodenectomy,'pancreatoduodenectomy','Whipple's operation',and'minimally invasive surgery'.Reference lists from the included articles were manually checked for any additional studies,which were included when appropriate.Delphi method was used to establish expert consensus and the AGREE II-GRS Instrument was applied to assess the methodological quality and externally validate the final statements.The statements were further discussed during a one-day face-to-face meeting at the 1st Summit on Minimally Invasive Pancreatico-Biliary Surgery in Wuhan,China.Findings:Twenty-eight international experts from 8 countries constructed the expert panel.Sixteen statements were produced by the members of the expert panel.At least 80%of responders agreed with the majority(80%)of statements.Other than three randomized controlled trials published to date,most evidences were based on level 3 or 4 studies according to the AGREE II-GRS Instrument.Conclusions and Relevance:The Wuhan international expert consensus meeting on LPD has produced a set of clinical practice statements for the safe development and progression of LP
文摘Nasopharyngeal carcinoma(NPC)is a malignant epithelial tumor originating in the nasopharynx and has a high incidence in Southeast Asia and North Africa.To develop these comprehensive guidelines for the diagnosis and management of NPC,the Chinese Society of Clinical Oncology(CSCO)arranged a multi-disciplinary team comprising of experts from all sub-specialties of NPC to write,discuss,and revise the guidelines.Based on the findings of evidencebased medicine in China and abroad,domestic experts have iteratively developed these guidelines to provide proper management of NPC.Overall,the guidelines describe the screening,clinical and pathological diagnosis,staging and risk assessment,therapies,and follow-up of NPC,which aim to improve the management of NPC.
文摘Detecting and segmenting salient objects from natural scenes, often referred to as salient object detection, has attracted great interest in computer vision. While many models have been proposed and several applications have emerged, a deep understanding of achievements and issues remains lacking. We aim to provide a comprehensive review of recent progress in salient object detection and situate this field among other closely related areas such as generic scene segmentation, object proposal generation, and saliency for fixation prediction. Covering 228 publications, we survey i) roots, key concepts, and tasks, ii) core techniques and main modeling trends, and iii) datasets and evaluation metrics for salient object detection. We also discuss open problems such as evaluation metrics and dataset bias in model performance, and suggest future research directions.