Foamed concrete has a good energy absorption capability and can be used as seismic isolation material for tunnels. This study aims to investigate the mechanical properties and associated seismic isolation effects of f...Foamed concrete has a good energy absorption capability and can be used as seismic isolation material for tunnels. This study aims to investigate the mechanical properties and associated seismic isolation effects of foamed concrete layer in rock tunnel. For this, a series of uniaxial/triaxial compression tests was conducted to understand the effects of concrete density, confining stress and strain rate on the mechanical properties of foamed concrete. The direct shear tests were also performed to investigate the effects of concrete density and normal stress on the nonlinear behaviors of foamed concrete layer-lining interface. The test results showed that the mechanical properties of foamed concrete are significantly influenced by the concrete density. The foamed concrete also has high volumetric compressibility and strain-rate dependence. The peak stress. residual stress. shear stiffness and residual friction coefficient of the foamed concrete layer-lining interface are influenced by the foamed concrete density and normal stress applied. Then, a crushable foam constitutive model was constructed using ABAQUS software and a composite exponential model was also established to study the relationship between shear stress and shear displacement of the interface, in which their parameters were fitted based on the experimental results. Finally, a parametric analysis using the finite element method(FEM) was conducted to understand the influence of foamed concrete layer properties on the seismic isolation effect, including the density and thickness of the layer as well as the shear stiffness and residual friction coefficient of the interface. It was revealed that lower density and greater thickness in addition to smaller shear stiffness or residual friction coefficient of the foamed concrete layer could yield better seismic isolation effect, and the influences of the first two tend to be more significant.展开更多
Prediction of bacteria-carrying particle （BCP） dispersion and particle distribution released from staffmem- bers in an operating room （OR） is very important for creating and sustaining a safe indoor environment. P...Prediction of bacteria-carrying particle （BCP） dispersion and particle distribution released from staffmem- bers in an operating room （OR） is very important for creating and sustaining a safe indoor environment. Postoperative wound infections cause significant morbidity and mortality, and contribute to increased hospitalization time. Increasing the number of personnel within the OR disrupts the ventilation airflow pattern and causes enhanced contamination risk in the area of an open wound. Whether the amount of staffwithin the OR influences the BCP distribution in the surgical zone has rarely been investigated. This study was conducted to explore the influence of the number of personnel in the OR on the airflow field and the BCP distribution. This was performed by applying a numerical calculation to map the airflow field and Lagrangian particle tracking （LPT） for the BCP phase. The results are reported both for active sampling and passive monitoring approaches. Not surprisingly, a growing trend in the BCP concentration （cfu/ms） was observed as the amount of staff in the OR increased. Passive sampling shows unpredictable results due to the sedimentation rate, especially for small particles （5-10 i^m）. Risk factors for surgical site infections （SSls） must be well understood to develop more effective prevention programs.展开更多
In the quest for a sustainable and abundant energy source, nuclear fusion technology stands as a beacon of hope. This study introduces a groundbreaking quantum mechanically effective induction system designed for magn...In the quest for a sustainable and abundant energy source, nuclear fusion technology stands as a beacon of hope. This study introduces a groundbreaking quantum mechanically effective induction system designed for magnetic plasma confinement within fusion reactors. The pursuit of clean energy, essential to combat climate change, hinges on the ability to harness nuclear fusion efficiently. Traditional approaches have faced challenges in plasma stability and energy efficiency. The novel induction system presented here not only addresses these issues but also transforms fusion reactors into integrated construction systems. This innovation promises compact fusion reactors, marking a significant step toward a clean and limitless energy future, free from the constraints of traditional power sources. This revolutionary quantum induction system redefines plasma confinement in fusion reactors, unlocking clean, compact, and efficient energy production.展开更多
Data processing and climate characterisation to study its impact is becoming difficult due to insufficient and unavailable data,especially in developing countries.Understanding climate’s impact on burnt areas in Ghan...Data processing and climate characterisation to study its impact is becoming difficult due to insufficient and unavailable data,especially in developing countries.Understanding climate’s impact on burnt areas in Ghana(Guinea-savannah(GSZ)and Forest-savannah Mosaic zones(FSZ))leads us to opt for machine learning.Through Google Earth Engine(GEE),rainfall(PR),maximum temperature(Tmax),minimum temperature(Tmin),average temperature(Tmean),Palmer Drought Severity Index(PDSI),relative humidity(RH),wind speed(WS),soil moisture(SM),actual evapotranspiration(ETA)and reference evapotranspiration(ETR)have been acquired through CHIRPS(Climate Hazards group Infrared Precipitation with Stations),FLDAS dataset(Famine Early Warning Systems Network(FEWS NET)Land Data Assimilation System)and TerraClimate platform from 1991 to 2021.The objective is to analyse the link and the contribution of climatic and environmental parameters on wildfire spread in GSZ and FSZ in Ghana.Variables were analysed(area burnt and the number of activefires)through Spearman correlation and the cross-correlation function(CCF)(2001 to 2021).The tests(Mann-Kendall and Sens’s slope trend test,Pettitt test and the Lee and Heghinian test)showed the overall decrease in rainfall and increase in temperature respectively(-0.1 mm;+0.8℃)in GSZ and(-0.9 mm;+0.3℃)in FSZ.In terms of impact,PR,ETR,FDI,Tmean,Tmax,Tmin,RH,ETA and SM contribute tofire spread.Through the codes developed,researchers and decision-makers could update them at different times easily to monitor climate variability and its impact onfires.展开更多
An important way to address global food security is to make better use of the food already produced. Since at least one third of global food is wasted before consumption, there are enormous incentives to cut this wast...An important way to address global food security is to make better use of the food already produced. Since at least one third of global food is wasted before consumption, there are enormous incentives to cut this waste and create a more sustainable food system. This paper focuses upon saving food loss at the supermarket level in the US and channeling this food stream in new and efficient ways to those in hunger. A more comprehensive Food System-Sensitive Methodology has been used to pilot and evaluate a surplus food management program that diverts culled fresh fruits and vegetables from grocery stores that would otherwise be disposed of in landfills. Instead, produce is processed for donation or for new businesses. Nearly 35,000 pounds of produce was culled from a grocery store chain in Philadelphia. Twenty-five percent of this was not suitable for culinary uses, ten percent consisted of relatively small quantities of food that did not warrant further research, and about 33 percent is suitable for use at area food shelters and pantries. An experimental sample taken from the remaining 15,000 pounds was used for recipe research and development for diversion to new commercial enterprises. We analyzed a scenario where a supermarket receives $0.25 per pound for culled produce, generating about $8700 dollars in average monthly revenue while eliminating disposal costs. New commercial possibilities for the unused food were then explored. The scenario included community-based enterprises that could process the produce into value-added products that could be wholesaled back to the store at sufficient profits to support 2 - 4 community employees. Extrapolating these results to the approximately 38,000 large supermarkets in the United States suggests that much of the 1,100,000,000 pounds of produce that is currently sent to landfills can be repurposed. If diverted to new foods each of the 46.1 million SNAP recipients could figuratively receive an equivalent of 24 pounds of fruit and vegetable products per annum. This initial展开更多
<span style="font-family:Verdana;">Capsular contracture is a frequent complication in the postoperative period of breast implantation. It usually accompanies the appearance of a firm breast that can pr...<span style="font-family:Verdana;">Capsular contracture is a frequent complication in the postoperative period of breast implantation. It usually accompanies the appearance of a firm breast that can progress to pain, distortion, and asymmetry of the breasts, requiring surgical revision. The present study is a case report. A 58-year-old woman with a medical diagnosis of capsular contracture of the right breast evidenced by ultrasound. She was referred to the physiotherapy clinic in October 2019 with an initial complaint of pain on palpation, swelling, and stiffness in her right breast. The patient was evaluated and the MAC</span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><sup><span style="font-family:Verdana;"><span style="font-family:Verdana;">ò</span></span></sup></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> method was used to treat capsular contracture. For this, 12 sessions of photodynamic therapy were carried out. The treatment included the use of LED by doping: red (300</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s), violet (60</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s) and blue (120</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s), with the use of 1% methylene blue in target areas, three times a week. The patient had the beginning of symptoms’ remission in the fourth visit and total remission in the 12th visit. It was concluded that the use of photodynamic therapy using the MAC</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><sup><span style展开更多
The in vitro study of tetracannabinolic acid(THCA)derivatives ALAM027 and ALAM108 was carried out on the following human tumor cells:T47D(breast,ductal carcinoma),PC-3(prostate,adenocarcinoma),HT 29(colorectal carcino...The in vitro study of tetracannabinolic acid(THCA)derivatives ALAM027 and ALAM108 was carried out on the following human tumor cells:T47D(breast,ductal carcinoma),PC-3(prostate,adenocarcinoma),HT 29(colorectal carcinoma),Caco-2(colon,adenocarcinoma),A549(lung,carcinoma),U87MG(human glioblastoma)and U266B1(multiple myeloma).The in vitro effects of THCA derivatives ALAM027 and ALAM108 on cell growth inhibition and IC50 values were measured using the CellTiter Glo assay.The ALAM027 compound showed good growth inhibition in all cell lines tested with the exception of U87MG cells.The ALAM108 compound also suppressed the growth of U87 MG cells but had little effect on T47D tumor cells.In vitro studies of THCA derivatives ALAM027 and ALAM108 showed antitumor activity in all cell lines tested.The difference in the activity of these compounds in relation to the T47D and U87MG tumor cells may be indicative of different functional mechanisms.展开更多
BACKGROUND Incidence of cholangiocarcinoma(CCA)is rising,with overall prognosis remaining very poor.Reasons for the high mortality of CCA include its late presentation in most patients,when curative options are no lon...BACKGROUND Incidence of cholangiocarcinoma(CCA)is rising,with overall prognosis remaining very poor.Reasons for the high mortality of CCA include its late presentation in most patients,when curative options are no longer feasible,and poor response to systemic therapies for advanced disease.Late presentation presents a large barrier to improving outcomes and is often associated with diagnosis via mergency presentation(EP).Earlier diagnoses may be made by Two Week Wait(TWW)referrals through General practitioner(GP).We hypothesise that TWW referrals and EP routes to diagnosis differ across regions in England.AIM To investigate routes to diagnosis of CCA over time,regional variation and influencing factors.METHODS We linked patient records from the National Cancer Registration Dataset to Hospital Episode Statistics,Cancer Waiting Times and Cancer Screening Programme datasets to define routes to diagnosis and certain patient characteristics for patients diagnosed 2006-2017 in England.We used linear probability models to investigate geographic variation by assessing the proportions of patients diagnosed via TWW referral or EP across Cancer Alliances in England,adjusting for potential confounders.Correlation between the proportion of people diagnosed by TWW referral and EP was investigated with Spearman’s correlation coefficient.RESULTS Of 23632 patients diagnosed between 2006-2017 in England,the most common route to diagnosis was EP(49.6%).Non-TWW GP referrals accounted for 20.5%of diagnosis routes,13.8%were diagnosed by TWW referral,and the remainder 16.2%were diagnosed via an‘other’or Unknown route.The proportion diagnosed via a TWW referral doubled between 2006-2017 rising from 9.9%to 19.8%,conversely EP diagnosis route declined,falling from 51.3%to 46.0%.Statistically significant variation in both the TWW referral and EP proportions was found across Cancer Alliances.Age,presence of comorbidity and underlying liver disease were independently associated with both a lower proportion of patients diagnosed via TWW展开更多
At present China-U.S.trade relations are in a state of confusion.Although both countries have gained tremendous benefits from the bilateral trade relationship,some Americans have intentionally distorted some basic fac...At present China-U.S.trade relations are in a state of confusion.Although both countries have gained tremendous benefits from the bilateral trade relationship,some Americans have intentionally distorted some basic facts regarding China-U.S.trade relations. Based on an analysis of some official and nonofficial research reports published in the United States,this article holds that the China-U.S.trade imbalance is the symptom of a bigger issue stemming from the contradiction between the United States as the world's sole superpower and China as an emerging power.Economic globalisation came about due to the needs of western developed countries represented by the United States to boost economic development.Only by seizing the opportunities of economic globalisation, has China gained strong economic growth. Such a development is changing the world political,economic,military and cultural landscape that have been shaped since the post-cold-war era,and has to some extent raised doubt or suspicion on the part of the United States and its western allies.This is a manifestation of how unprepared some people in the United States and other western countries are in the face of China's rapid development and rising status.So,their immediate reaction has been to seek protection for themselves,and try their utmost to prevent China's rapid growth from impacting on the international framework and their vested interests.展开更多
Web crawlers have evolved from performing a meagre task of collecting statistics,security testing,web indexing and numerous other examples.The size and dynamism of the web are making crawling an interesting and challe...Web crawlers have evolved from performing a meagre task of collecting statistics,security testing,web indexing and numerous other examples.The size and dynamism of the web are making crawling an interesting and challenging task.Researchers have tackled various issues and challenges related to web crawling.One such issue is efficiently discovering hidden web data.Web crawler’s inability to work with form-based data,lack of benchmarks and standards for both performance measures and datasets for evaluation of the web crawlers make it still an immature research domain.The applications like vertical portals and data integration require hidden web crawling.Most of the existing methods are based on returning top k matches that makes exhaustive crawling difficult.The documents which are ranked high will be returned multiple times.The low ranked documents have slim chances of being retrieved.Discovering the hidden web sources and ranking them based on relevance is a core component of hidden web crawlers.The problem of ranking bias,heuristic approach and saturation of ranking algorithm led to low coverage.This research represents an enhanced ranking algorithm based on the triplet formula for prioritizing hidden websites to increase the coverage of the hidden web crawler.展开更多
If there were not the economic crisis, Chinese economy were not affected, the market had stayed the same as two years ago or even earlier,economies in the eastern coastal areas had maintained strong,Midwestern economy...If there were not the economic crisis, Chinese economy were not affected, the market had stayed the same as two years ago or even earlier,economies in the eastern coastal areas had maintained strong,Midwestern economy had been a plant with plenty of shadow,inner land ports still fed eastern economy,maybe this unchanging condition will cause a展开更多
Introduction Industrial tools using diamonds were first introduced in the Korean market about thirty years ago.In the beginning,diamond tools were primarily used in industries dealing with stone materials.Today,howeve...Introduction Industrial tools using diamonds were first introduced in the Korean market about thirty years ago.In the beginning,diamond tools were primarily used in industries dealing with stone materials.Today,however, they are focusing more on industrial tools than construction tools.The production trend of the展开更多
基金the financial support from the National Basic Research Program of China(973 Program)(Grant No.2015CB057906)the National Natural Science Foundation of China(Grant No.51409245)
文摘Foamed concrete has a good energy absorption capability and can be used as seismic isolation material for tunnels. This study aims to investigate the mechanical properties and associated seismic isolation effects of foamed concrete layer in rock tunnel. For this, a series of uniaxial/triaxial compression tests was conducted to understand the effects of concrete density, confining stress and strain rate on the mechanical properties of foamed concrete. The direct shear tests were also performed to investigate the effects of concrete density and normal stress on the nonlinear behaviors of foamed concrete layer-lining interface. The test results showed that the mechanical properties of foamed concrete are significantly influenced by the concrete density. The foamed concrete also has high volumetric compressibility and strain-rate dependence. The peak stress. residual stress. shear stiffness and residual friction coefficient of the foamed concrete layer-lining interface are influenced by the foamed concrete density and normal stress applied. Then, a crushable foam constitutive model was constructed using ABAQUS software and a composite exponential model was also established to study the relationship between shear stress and shear displacement of the interface, in which their parameters were fitted based on the experimental results. Finally, a parametric analysis using the finite element method(FEM) was conducted to understand the influence of foamed concrete layer properties on the seismic isolation effect, including the density and thickness of the layer as well as the shear stiffness and residual friction coefficient of the interface. It was revealed that lower density and greater thickness in addition to smaller shear stiffness or residual friction coefficient of the foamed concrete layer could yield better seismic isolation effect, and the influences of the first two tend to be more significant.
文摘Prediction of bacteria-carrying particle （BCP） dispersion and particle distribution released from staffmem- bers in an operating room （OR） is very important for creating and sustaining a safe indoor environment. Postoperative wound infections cause significant morbidity and mortality, and contribute to increased hospitalization time. Increasing the number of personnel within the OR disrupts the ventilation airflow pattern and causes enhanced contamination risk in the area of an open wound. Whether the amount of staffwithin the OR influences the BCP distribution in the surgical zone has rarely been investigated. This study was conducted to explore the influence of the number of personnel in the OR on the airflow field and the BCP distribution. This was performed by applying a numerical calculation to map the airflow field and Lagrangian particle tracking （LPT） for the BCP phase. The results are reported both for active sampling and passive monitoring approaches. Not surprisingly, a growing trend in the BCP concentration （cfu/ms） was observed as the amount of staff in the OR increased. Passive sampling shows unpredictable results due to the sedimentation rate, especially for small particles （5-10 i^m）. Risk factors for surgical site infections （SSls） must be well understood to develop more effective prevention programs.
文摘In the quest for a sustainable and abundant energy source, nuclear fusion technology stands as a beacon of hope. This study introduces a groundbreaking quantum mechanically effective induction system designed for magnetic plasma confinement within fusion reactors. The pursuit of clean energy, essential to combat climate change, hinges on the ability to harness nuclear fusion efficiently. Traditional approaches have faced challenges in plasma stability and energy efficiency. The novel induction system presented here not only addresses these issues but also transforms fusion reactors into integrated construction systems. This innovation promises compact fusion reactors, marking a significant step toward a clean and limitless energy future, free from the constraints of traditional power sources. This revolutionary quantum induction system redefines plasma confinement in fusion reactors, unlocking clean, compact, and efficient energy production.
文摘Data processing and climate characterisation to study its impact is becoming difficult due to insufficient and unavailable data,especially in developing countries.Understanding climate’s impact on burnt areas in Ghana(Guinea-savannah(GSZ)and Forest-savannah Mosaic zones(FSZ))leads us to opt for machine learning.Through Google Earth Engine(GEE),rainfall(PR),maximum temperature(Tmax),minimum temperature(Tmin),average temperature(Tmean),Palmer Drought Severity Index(PDSI),relative humidity(RH),wind speed(WS),soil moisture(SM),actual evapotranspiration(ETA)and reference evapotranspiration(ETR)have been acquired through CHIRPS(Climate Hazards group Infrared Precipitation with Stations),FLDAS dataset(Famine Early Warning Systems Network(FEWS NET)Land Data Assimilation System)and TerraClimate platform from 1991 to 2021.The objective is to analyse the link and the contribution of climatic and environmental parameters on wildfire spread in GSZ and FSZ in Ghana.Variables were analysed(area burnt and the number of activefires)through Spearman correlation and the cross-correlation function(CCF)(2001 to 2021).The tests(Mann-Kendall and Sens’s slope trend test,Pettitt test and the Lee and Heghinian test)showed the overall decrease in rainfall and increase in temperature respectively(-0.1 mm;+0.8℃)in GSZ and(-0.9 mm;+0.3℃)in FSZ.In terms of impact,PR,ETR,FDI,Tmean,Tmax,Tmin,RH,ETA and SM contribute tofire spread.Through the codes developed,researchers and decision-makers could update them at different times easily to monitor climate variability and its impact onfires.
文摘An important way to address global food security is to make better use of the food already produced. Since at least one third of global food is wasted before consumption, there are enormous incentives to cut this waste and create a more sustainable food system. This paper focuses upon saving food loss at the supermarket level in the US and channeling this food stream in new and efficient ways to those in hunger. A more comprehensive Food System-Sensitive Methodology has been used to pilot and evaluate a surplus food management program that diverts culled fresh fruits and vegetables from grocery stores that would otherwise be disposed of in landfills. Instead, produce is processed for donation or for new businesses. Nearly 35,000 pounds of produce was culled from a grocery store chain in Philadelphia. Twenty-five percent of this was not suitable for culinary uses, ten percent consisted of relatively small quantities of food that did not warrant further research, and about 33 percent is suitable for use at area food shelters and pantries. An experimental sample taken from the remaining 15,000 pounds was used for recipe research and development for diversion to new commercial enterprises. We analyzed a scenario where a supermarket receives $0.25 per pound for culled produce, generating about $8700 dollars in average monthly revenue while eliminating disposal costs. New commercial possibilities for the unused food were then explored. The scenario included community-based enterprises that could process the produce into value-added products that could be wholesaled back to the store at sufficient profits to support 2 - 4 community employees. Extrapolating these results to the approximately 38,000 large supermarkets in the United States suggests that much of the 1,100,000,000 pounds of produce that is currently sent to landfills can be repurposed. If diverted to new foods each of the 46.1 million SNAP recipients could figuratively receive an equivalent of 24 pounds of fruit and vegetable products per annum. This initial
文摘<span style="font-family:Verdana;">Capsular contracture is a frequent complication in the postoperative period of breast implantation. It usually accompanies the appearance of a firm breast that can progress to pain, distortion, and asymmetry of the breasts, requiring surgical revision. The present study is a case report. A 58-year-old woman with a medical diagnosis of capsular contracture of the right breast evidenced by ultrasound. She was referred to the physiotherapy clinic in October 2019 with an initial complaint of pain on palpation, swelling, and stiffness in her right breast. The patient was evaluated and the MAC</span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><sup><span style="font-family:Verdana;"><span style="font-family:Verdana;">ò</span></span></sup></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> method was used to treat capsular contracture. For this, 12 sessions of photodynamic therapy were carried out. The treatment included the use of LED by doping: red (300</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s), violet (60</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s) and blue (120</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s), with the use of 1% methylene blue in target areas, three times a week. The patient had the beginning of symptoms’ remission in the fourth visit and total remission in the 12th visit. It was concluded that the use of photodynamic therapy using the MAC</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><sup><span style
基金This work was funded from the AL&AM Pharmachem Ltd.company's own funds.(Grant ALAM2019-001).
文摘The in vitro study of tetracannabinolic acid(THCA)derivatives ALAM027 and ALAM108 was carried out on the following human tumor cells:T47D(breast,ductal carcinoma),PC-3(prostate,adenocarcinoma),HT 29(colorectal carcinoma),Caco-2(colon,adenocarcinoma),A549(lung,carcinoma),U87MG(human glioblastoma)and U266B1(multiple myeloma).The in vitro effects of THCA derivatives ALAM027 and ALAM108 on cell growth inhibition and IC50 values were measured using the CellTiter Glo assay.The ALAM027 compound showed good growth inhibition in all cell lines tested with the exception of U87MG cells.The ALAM108 compound also suppressed the growth of U87 MG cells but had little effect on T47D tumor cells.In vitro studies of THCA derivatives ALAM027 and ALAM108 showed antitumor activity in all cell lines tested.The difference in the activity of these compounds in relation to the T47D and U87MG tumor cells may be indicative of different functional mechanisms.
文摘BACKGROUND Incidence of cholangiocarcinoma(CCA)is rising,with overall prognosis remaining very poor.Reasons for the high mortality of CCA include its late presentation in most patients,when curative options are no longer feasible,and poor response to systemic therapies for advanced disease.Late presentation presents a large barrier to improving outcomes and is often associated with diagnosis via mergency presentation(EP).Earlier diagnoses may be made by Two Week Wait(TWW)referrals through General practitioner(GP).We hypothesise that TWW referrals and EP routes to diagnosis differ across regions in England.AIM To investigate routes to diagnosis of CCA over time,regional variation and influencing factors.METHODS We linked patient records from the National Cancer Registration Dataset to Hospital Episode Statistics,Cancer Waiting Times and Cancer Screening Programme datasets to define routes to diagnosis and certain patient characteristics for patients diagnosed 2006-2017 in England.We used linear probability models to investigate geographic variation by assessing the proportions of patients diagnosed via TWW referral or EP across Cancer Alliances in England,adjusting for potential confounders.Correlation between the proportion of people diagnosed by TWW referral and EP was investigated with Spearman’s correlation coefficient.RESULTS Of 23632 patients diagnosed between 2006-2017 in England,the most common route to diagnosis was EP(49.6%).Non-TWW GP referrals accounted for 20.5%of diagnosis routes,13.8%were diagnosed by TWW referral,and the remainder 16.2%were diagnosed via an‘other’or Unknown route.The proportion diagnosed via a TWW referral doubled between 2006-2017 rising from 9.9%to 19.8%,conversely EP diagnosis route declined,falling from 51.3%to 46.0%.Statistically significant variation in both the TWW referral and EP proportions was found across Cancer Alliances.Age,presence of comorbidity and underlying liver disease were independently associated with both a lower proportion of patients diagnosed via TWW
文摘At present China-U.S.trade relations are in a state of confusion.Although both countries have gained tremendous benefits from the bilateral trade relationship,some Americans have intentionally distorted some basic facts regarding China-U.S.trade relations. Based on an analysis of some official and nonofficial research reports published in the United States,this article holds that the China-U.S.trade imbalance is the symptom of a bigger issue stemming from the contradiction between the United States as the world's sole superpower and China as an emerging power.Economic globalisation came about due to the needs of western developed countries represented by the United States to boost economic development.Only by seizing the opportunities of economic globalisation, has China gained strong economic growth. Such a development is changing the world political,economic,military and cultural landscape that have been shaped since the post-cold-war era,and has to some extent raised doubt or suspicion on the part of the United States and its western allies.This is a manifestation of how unprepared some people in the United States and other western countries are in the face of China's rapid development and rising status.So,their immediate reaction has been to seek protection for themselves,and try their utmost to prevent China's rapid growth from impacting on the international framework and their vested interests.
基金Taif University Researchers Supporting Project number(TURSP-2020/98),Taif University,Taif,Saudi Arabia.
文摘Web crawlers have evolved from performing a meagre task of collecting statistics,security testing,web indexing and numerous other examples.The size and dynamism of the web are making crawling an interesting and challenging task.Researchers have tackled various issues and challenges related to web crawling.One such issue is efficiently discovering hidden web data.Web crawler’s inability to work with form-based data,lack of benchmarks and standards for both performance measures and datasets for evaluation of the web crawlers make it still an immature research domain.The applications like vertical portals and data integration require hidden web crawling.Most of the existing methods are based on returning top k matches that makes exhaustive crawling difficult.The documents which are ranked high will be returned multiple times.The low ranked documents have slim chances of being retrieved.Discovering the hidden web sources and ranking them based on relevance is a core component of hidden web crawlers.The problem of ranking bias,heuristic approach and saturation of ranking algorithm led to low coverage.This research represents an enhanced ranking algorithm based on the triplet formula for prioritizing hidden websites to increase the coverage of the hidden web crawler.
文摘If there were not the economic crisis, Chinese economy were not affected, the market had stayed the same as two years ago or even earlier,economies in the eastern coastal areas had maintained strong,Midwestern economy had been a plant with plenty of shadow,inner land ports still fed eastern economy,maybe this unchanging condition will cause a
文摘Introduction Industrial tools using diamonds were first introduced in the Korean market about thirty years ago.In the beginning,diamond tools were primarily used in industries dealing with stone materials.Today,however, they are focusing more on industrial tools than construction tools.The production trend of the
