Phytochemical investigation of the leaves of Premna microphylla Turcz led to the isolation of 13 known compounds. Based on spectroscopic and chemical evidences, their structures were identified as diosmetin （1）, blu...Phytochemical investigation of the leaves of Premna microphylla Turcz led to the isolation of 13 known compounds. Based on spectroscopic and chemical evidences, their structures were identified as diosmetin （1）, blumenol A （2）, （3S,5R,6S,7E,9R）-5,6-epoxy-3,9-dihydroxy-7-megastigmene （3）, 3β-hydroxy-5a,6a-epoxy-γ-megastigmen-9-one （4）, ixerol B （5）, （-）-dehydrovomifoliol （6）, 3S,5R-dihydroxy-6S,7-megastigmadien-9-one （7）, loliotide （8）, （＋）-dehydrololiolide （9）, （＋）-medioresinol （10）, 4-oxopinoresinol （11）, tormentic acid （12）, and indole-3-carboxylic acid （13）. Compounds 2-13 described above were isolated from this genus for the first time.展开更多
基金National Natural Science Foundation of China(Grant No.31270390)Program for New Century Excellent Talents in University(Grant No.NCET-08-0224)
文摘Phytochemical investigation of the leaves of Premna microphylla Turcz led to the isolation of 13 known compounds. Based on spectroscopic and chemical evidences, their structures were identified as diosmetin （1）, blumenol A （2）, （3S,5R,6S,7E,9R）-5,6-epoxy-3,9-dihydroxy-7-megastigmene （3）, 3β-hydroxy-5a,6a-epoxy-γ-megastigmen-9-one （4）, ixerol B （5）, （-）-dehydrovomifoliol （6）, 3S,5R-dihydroxy-6S,7-megastigmadien-9-one （7）, loliotide （8）, （＋）-dehydrololiolide （9）, （＋）-medioresinol （10）, 4-oxopinoresinol （11）, tormentic acid （12）, and indole-3-carboxylic acid （13）. Compounds 2-13 described above were isolated from this genus for the first time.
基金supported by the National Natural Science Foundation of China (Nos. 30973864 and 81173065)Ph.D. Programs Foundation of the Ministry of Education of China (No. 20090142110021)~~
