滇池是云南高原最大的淡水湖,是昆明地区工农业生产及人民生活用水的水源,又是昆明市的重要风景区。近年来,滇池水质污染,越来越引起人们的关注。昆明市的工业废水和生活污水经大观河等流入滇池,其中有毒有害物质多达30多种,包括镉、汞...滇池是云南高原最大的淡水湖,是昆明地区工农业生产及人民生活用水的水源,又是昆明市的重要风景区。近年来,滇池水质污染,越来越引起人们的关注。昆明市的工业废水和生活污水经大观河等流入滇池,其中有毒有害物质多达30多种,包括镉、汞、砷、铅、铬、氟、有机磷、氰化物等。其中砷(Léonard et al., 1980;Katsuhiko,展开更多
2011年12月5日在云南省个旧市蔓耗镇(N23°00‘43.0",E103°26‘18.9",海拔350m)采集到高氏缺齿鼩(Chodsigoa caovansunga Lunde,Musser and Son,2003)标本1号。该物种为中国新纪录并且是其在模式产地(越南河江省Mt.T...2011年12月5日在云南省个旧市蔓耗镇(N23°00‘43.0",E103°26‘18.9",海拔350m)采集到高氏缺齿鼩(Chodsigoa caovansunga Lunde,Musser and Son,2003)标本1号。该物种为中国新纪录并且是其在模式产地(越南河江省Mt.Tay Con LinhⅡ山)以外的首个分布纪录。该标本头体长、尾长及颅全长明显大于模式产地的标本,线粒体cyt-b序列(JX508288)与地模标本相似度为98.6%。采集地生境为沟谷雨林,干扰类型为香蕉种植。展开更多
Recent molecular cytogenetic studies demonstrate that extensive centromere-telomere fusions are the main chromosomal rearrangements underlying the karyotypic evolution of extant muntjacs. Although the molecular mechan...Recent molecular cytogenetic studies demonstrate that extensive centromere-telomere fusions are the main chromosomal rearrangements underlying the karyotypic evolution of extant muntjacs. Although the molecular mechanism of tandem fusions remains unknown, satellite DNA is believed to have facilitated chromosome fusions by non-allelic homologous recombination. Previous studies detected non-random hybridization signals of cloned satellite DNA at the postulated fusion sites on the chromosomes in Indian and Chinese muntjacs. But the genomic distribution and organization of satellite DNAs in other muntjacs have not been investigated. In this study, we have isolated four satellite DNA clones （BMCS, BM700, BM 1.1 k and FM700） from the black muntjac （Muntiacus crinifrons） and Fea＇s muntjac （M. feae）, and hybridized these four clones onto chromosomes of four muntjac species （M. reevesi, M. crinifrons, M. gongshanenisis and M. feae）. Besides the predominant centromeric signals, non-random interstitial hybridization signals from satellite I and II DNA clones （BMC5, BM700 and FM700） were also observed on the arms of chromosomes of these four muntjacs. Our results provide additional support for the notion that the karyotypes of M. crinifrons, M. feae and M. gongshanensis have evolved from a 2n = 70 ancestral karyotype by a series of chromosome fusions.展开更多
Previous research on gene expression analysis and association tests have suggested that RELN is a risk gene for schizophrenia in world populations.Based on the reported down-regulation of RELN in schizophrenia patient...Previous research on gene expression analysis and association tests have suggested that RELN is a risk gene for schizophrenia in world populations.Based on the reported down-regulation of RELN in schizophrenia patients compared with normal subjects,we speculated that variants in the RELN promoter region may confer risk for schizophrenia.In this study,we investigated the associations of three SNPs in the promoter region of RELN with schizophrenia in a case-control sample from southwestern China（940 cases and 13 69 controls）.The results suggested that none of the SNPs showed significant associations in our sample,indicating the risk variants for schizophrenia in RELN may not be located in the promoter region.We also performed meta-analysis by combining our data with previously reported data on the Chinese population with a total sample size of 2 843 individuals,and the result remained nonsignificant.Collectively,our results suggested variants in the RELN promoter may not harbor risk SNPs associated with schizophrenia in the Chinese population.展开更多
文摘滇池是云南高原最大的淡水湖,是昆明地区工农业生产及人民生活用水的水源,又是昆明市的重要风景区。近年来,滇池水质污染,越来越引起人们的关注。昆明市的工业废水和生活污水经大观河等流入滇池,其中有毒有害物质多达30多种,包括镉、汞、砷、铅、铬、氟、有机磷、氰化物等。其中砷(Léonard et al., 1980;Katsuhiko,
基金Support for Taxonomy by the Chinese Academy of Sciences(KSCXZ-YW-Z-0923)National Natural Science Foundation of China (30370193)
文摘2011年12月5日在云南省个旧市蔓耗镇(N23°00‘43.0",E103°26‘18.9",海拔350m)采集到高氏缺齿鼩(Chodsigoa caovansunga Lunde,Musser and Son,2003)标本1号。该物种为中国新纪录并且是其在模式产地(越南河江省Mt.Tay Con LinhⅡ山)以外的首个分布纪录。该标本头体长、尾长及颅全长明显大于模式产地的标本,线粒体cyt-b序列(JX508288)与地模标本相似度为98.6%。采集地生境为沟谷雨林,干扰类型为香蕉种植。
基金the grant from the National Natural Science Foundation of China (30270719)
文摘Recent molecular cytogenetic studies demonstrate that extensive centromere-telomere fusions are the main chromosomal rearrangements underlying the karyotypic evolution of extant muntjacs. Although the molecular mechanism of tandem fusions remains unknown, satellite DNA is believed to have facilitated chromosome fusions by non-allelic homologous recombination. Previous studies detected non-random hybridization signals of cloned satellite DNA at the postulated fusion sites on the chromosomes in Indian and Chinese muntjacs. But the genomic distribution and organization of satellite DNAs in other muntjacs have not been investigated. In this study, we have isolated four satellite DNA clones （BMCS, BM700, BM 1.1 k and FM700） from the black muntjac （Muntiacus crinifrons） and Fea＇s muntjac （M. feae）, and hybridized these four clones onto chromosomes of four muntjac species （M. reevesi, M. crinifrons, M. gongshanenisis and M. feae）. Besides the predominant centromeric signals, non-random interstitial hybridization signals from satellite I and II DNA clones （BMC5, BM700 and FM700） were also observed on the arms of chromosomes of these four muntjacs. Our results provide additional support for the notion that the karyotypes of M. crinifrons, M. feae and M. gongshanensis have evolved from a 2n = 70 ancestral karyotype by a series of chromosome fusions.
文摘Previous research on gene expression analysis and association tests have suggested that RELN is a risk gene for schizophrenia in world populations.Based on the reported down-regulation of RELN in schizophrenia patients compared with normal subjects,we speculated that variants in the RELN promoter region may confer risk for schizophrenia.In this study,we investigated the associations of three SNPs in the promoter region of RELN with schizophrenia in a case-control sample from southwestern China（940 cases and 13 69 controls）.The results suggested that none of the SNPs showed significant associations in our sample,indicating the risk variants for schizophrenia in RELN may not be located in the promoter region.We also performed meta-analysis by combining our data with previously reported data on the Chinese population with a total sample size of 2 843 individuals,and the result remained nonsignificant.Collectively,our results suggested variants in the RELN promoter may not harbor risk SNPs associated with schizophrenia in the Chinese population.
基金全球环境基金会/世界银行项目(GEF-MSP grant No.TF051795)云南省发展和改革委员会项目(滇中主要湖泊土著特有鱼类迁地保育人工繁殖与持续利用试验示范)+2 种基金中国科学院西部之光项目(292006312D11033)云南省科技厅社会发展科技计划项目(2008CA001)国家重点基础研究发展计划项目(2007CB411600)
