目的实施有利于机械通气患者脱机的方法,缩短机械通气时间,促进患者早日康复。方法选择华中科技大学同济医学院附属同济医院呼吸内科重症监护病房(RICU)的机械通气患者为研究对象,将2018年1—11月入院的患者设为对照组,使用基于医生经...目的实施有利于机械通气患者脱机的方法,缩短机械通气时间,促进患者早日康复。方法选择华中科技大学同济医学院附属同济医院呼吸内科重症监护病房(RICU)的机械通气患者为研究对象,将2018年1—11月入院的患者设为对照组,使用基于医生经验判断的脱机方法脱机。2019年同期在院的患者设为观察组,实施程序化脱机方案,比较两组患者的脱机成功率、撤机时间、总机械通气时间、RICU住院时间、总住院时间和脱机后24h内再行机械通气的发生率。结果程序化脱机方案提高了成功脱机率(29.8%vs 53.22%),缩短了撤机时间(9.14h vs 3.64h),降低了总机械通气时间(9.43 d vs 5.88 d)和RICU住院日(39.50 d vs 16.06 d)。两组患者在死亡率(25.5%vs 20.97%)、脱机后24 h内再行机械通气发生率(21.43%vs 3.03%)以及总住院日(43.50 vs27.06)方面的差异无统计学意义(P>0.05)。结论程序化脱机方案可以改善患者照护结局,在没有或者缺乏专职的呼吸治疗师的情况下,可以考虑将程序化脱机方案交由接受了培训的护士来实施。展开更多
BACKGROUND Cardiovascular disease is the most prevalent disease worldwide and places a great burden on the health and economic welfare of patients.Cardiac surgery is an important way to treat cardiovascular disease,bu...BACKGROUND Cardiovascular disease is the most prevalent disease worldwide and places a great burden on the health and economic welfare of patients.Cardiac surgery is an important way to treat cardiovascular disease,but it can prolong mechanical ventilation time,intensive care unit(ICU)stay,and postoperative hospitalization for patients.Previous studies have demonstrated that preoperative inspiratory muscle training could decrease the incidence of postoperative pulmonary complications.AIM To explore the effect of preoperative inspiratory muscle training on mechanical ventilation time,length of ICU stay,and duration of postoperative hospitalization after cardiac surgery.METHODS A literature search of PubMed,Web of Science,Cochrane Library,EMBASE,China National Knowledge Infrastructure,WanFang,and the China Science and Technology journal VIP database was performed on April 13,2022.The data was independently extracted by two authors.The inclusion criteria were:(1)Randomized controlled trial;(2)Accessible as a full paper;(3)Patients who received cardiac surgery;(4)Preoperative inspiratory muscle training was implemented in these patients;(5)The study reported at least one of the following:Mechanical ventilation time,length of ICU stay,and/or duration of postoperative hospitalization;and(6)In English language.RESULTS We analyzed six randomized controlled trials with a total of 925 participants.The pooled mean difference of mechanical ventilation time was-0.45 h[95%confidence interval(CI):-1.59-0.69],which was not statistically significant between the intervention group and the control group.The pooled mean difference of length of ICU stay was 0.44 h(95%CI:-0.58-1.45).The pooled mean difference of postoperative hospitalization was-1.77 d in the intervention group vs the control group[95%CI:-2.41-(-1.12)].CONCLUSION Preoperative inspiratory muscle training may decrease the duration of postoperative hospitalization for patients undergoing cardiac surgery.More high-quality studies are needed to confirm our conclusion.展开更多
目的研究分析新生儿呼吸机相关性肺炎(VAP)的感染情况及特征表现,以及观察应用集束化护理干预对VAP发生率和机械通气时间的影响,旨在提高新生儿的存活率。方法选取2015年2月-2016年5月医院新生儿重症监护病房(Neonatal intensive care u...目的研究分析新生儿呼吸机相关性肺炎(VAP)的感染情况及特征表现,以及观察应用集束化护理干预对VAP发生率和机械通气时间的影响,旨在提高新生儿的存活率。方法选取2015年2月-2016年5月医院新生儿重症监护病房(Neonatal intensive care unit,NICU)收治的68例患儿,遵照随机分配原则进行数字奇偶分组,奇数纳入对照组,偶数纳入试验组,对照组应用常规机械通气护理干预措施,试验组则应用集束化护理干预,对比分析不同护理模式下患儿的VAP发生率和机械通气时间差异,同时分析VAP感染患儿的病原学特征。结果试验组患儿临床死亡率及VAP发生率分别为8.82%、8.82%,均低于对照组患儿的26.47%、26.47%,试验组患儿脱机成功率94.12%高于对照组患儿的76.47%(P<0.05);试验组患儿机械通气时间、NICU住院时间以及总治疗时间均低于对照组患儿(P<0.05);试验组患儿血气指标水平均优于对照组患儿(P<0.05);68例患儿中共12例发生VAP,病原菌分析结果显示革兰阴性菌为主要致病菌,同时革兰阳性菌与真菌均有一定的检出率。结论应用呼吸机辅助通气新生儿进行集束化护理干预,可有效降低VAP的发生率,同时明确VAP发生患儿主要致病菌可以避免抗菌药物滥用,改善患儿的预后情况,在临床治疗中应当引起重视。展开更多
Aim: To evaluate the correlation of blood lactate and mixed venous oxygen saturation to predict outcome in off-pump coronary artery bypass grafting. Method: This is a randomized study including 30 patients. Blood lact...Aim: To evaluate the correlation of blood lactate and mixed venous oxygen saturation to predict outcome in off-pump coronary artery bypass grafting. Method: This is a randomized study including 30 patients. Blood lactate and mixed venous oxygen saturation were measured in 4 groups of patients—number of grafts, presence or absence of left main coronary artery disease, ejection fraction and serum creatinine. Blood samples were taken before induction, after grafting, on intensive care unit admission, 24 hours and 48 hours after surgery. The measured blood lactate and mixed venous oxygen saturation are compared to assess the outcomes in terms of duration of ventilation and intensive care unit stay. Results: The blood lactate and mixed venous oxygen saturation values increased post operatively but no statistically significant difference in three groups— number of grafts, left main coronary artery disease and ejection fraction. In serum creatinine group, the blood lactate value was found to be statistically significant after grafting in patients with creatinine <1.5 mg/dl, however, there was a significant disparity in numbers. Conclusion: Mixed venous oxygen saturation is a better predictor of morbidity than blood lactate in terms of intensive care unit stay in patients undergoing off pump coronary artery bypass grafting.展开更多
文摘目的实施有利于机械通气患者脱机的方法,缩短机械通气时间,促进患者早日康复。方法选择华中科技大学同济医学院附属同济医院呼吸内科重症监护病房(RICU)的机械通气患者为研究对象,将2018年1—11月入院的患者设为对照组,使用基于医生经验判断的脱机方法脱机。2019年同期在院的患者设为观察组,实施程序化脱机方案,比较两组患者的脱机成功率、撤机时间、总机械通气时间、RICU住院时间、总住院时间和脱机后24h内再行机械通气的发生率。结果程序化脱机方案提高了成功脱机率(29.8%vs 53.22%),缩短了撤机时间(9.14h vs 3.64h),降低了总机械通气时间(9.43 d vs 5.88 d)和RICU住院日(39.50 d vs 16.06 d)。两组患者在死亡率(25.5%vs 20.97%)、脱机后24 h内再行机械通气发生率(21.43%vs 3.03%)以及总住院日(43.50 vs27.06)方面的差异无统计学意义(P>0.05)。结论程序化脱机方案可以改善患者照护结局,在没有或者缺乏专职的呼吸治疗师的情况下,可以考虑将程序化脱机方案交由接受了培训的护士来实施。
文摘BACKGROUND Cardiovascular disease is the most prevalent disease worldwide and places a great burden on the health and economic welfare of patients.Cardiac surgery is an important way to treat cardiovascular disease,but it can prolong mechanical ventilation time,intensive care unit(ICU)stay,and postoperative hospitalization for patients.Previous studies have demonstrated that preoperative inspiratory muscle training could decrease the incidence of postoperative pulmonary complications.AIM To explore the effect of preoperative inspiratory muscle training on mechanical ventilation time,length of ICU stay,and duration of postoperative hospitalization after cardiac surgery.METHODS A literature search of PubMed,Web of Science,Cochrane Library,EMBASE,China National Knowledge Infrastructure,WanFang,and the China Science and Technology journal VIP database was performed on April 13,2022.The data was independently extracted by two authors.The inclusion criteria were:(1)Randomized controlled trial;(2)Accessible as a full paper;(3)Patients who received cardiac surgery;(4)Preoperative inspiratory muscle training was implemented in these patients;(5)The study reported at least one of the following:Mechanical ventilation time,length of ICU stay,and/or duration of postoperative hospitalization;and(6)In English language.RESULTS We analyzed six randomized controlled trials with a total of 925 participants.The pooled mean difference of mechanical ventilation time was-0.45 h[95%confidence interval(CI):-1.59-0.69],which was not statistically significant between the intervention group and the control group.The pooled mean difference of length of ICU stay was 0.44 h(95%CI:-0.58-1.45).The pooled mean difference of postoperative hospitalization was-1.77 d in the intervention group vs the control group[95%CI:-2.41-(-1.12)].CONCLUSION Preoperative inspiratory muscle training may decrease the duration of postoperative hospitalization for patients undergoing cardiac surgery.More high-quality studies are needed to confirm our conclusion.
文摘目的研究分析新生儿呼吸机相关性肺炎(VAP)的感染情况及特征表现,以及观察应用集束化护理干预对VAP发生率和机械通气时间的影响,旨在提高新生儿的存活率。方法选取2015年2月-2016年5月医院新生儿重症监护病房(Neonatal intensive care unit,NICU)收治的68例患儿,遵照随机分配原则进行数字奇偶分组,奇数纳入对照组,偶数纳入试验组,对照组应用常规机械通气护理干预措施,试验组则应用集束化护理干预,对比分析不同护理模式下患儿的VAP发生率和机械通气时间差异,同时分析VAP感染患儿的病原学特征。结果试验组患儿临床死亡率及VAP发生率分别为8.82%、8.82%,均低于对照组患儿的26.47%、26.47%,试验组患儿脱机成功率94.12%高于对照组患儿的76.47%(P<0.05);试验组患儿机械通气时间、NICU住院时间以及总治疗时间均低于对照组患儿(P<0.05);试验组患儿血气指标水平均优于对照组患儿(P<0.05);68例患儿中共12例发生VAP,病原菌分析结果显示革兰阴性菌为主要致病菌,同时革兰阳性菌与真菌均有一定的检出率。结论应用呼吸机辅助通气新生儿进行集束化护理干预,可有效降低VAP的发生率,同时明确VAP发生患儿主要致病菌可以避免抗菌药物滥用,改善患儿的预后情况,在临床治疗中应当引起重视。
文摘Aim: To evaluate the correlation of blood lactate and mixed venous oxygen saturation to predict outcome in off-pump coronary artery bypass grafting. Method: This is a randomized study including 30 patients. Blood lactate and mixed venous oxygen saturation were measured in 4 groups of patients—number of grafts, presence or absence of left main coronary artery disease, ejection fraction and serum creatinine. Blood samples were taken before induction, after grafting, on intensive care unit admission, 24 hours and 48 hours after surgery. The measured blood lactate and mixed venous oxygen saturation are compared to assess the outcomes in terms of duration of ventilation and intensive care unit stay. Results: The blood lactate and mixed venous oxygen saturation values increased post operatively but no statistically significant difference in three groups— number of grafts, left main coronary artery disease and ejection fraction. In serum creatinine group, the blood lactate value was found to be statistically significant after grafting in patients with creatinine <1.5 mg/dl, however, there was a significant disparity in numbers. Conclusion: Mixed venous oxygen saturation is a better predictor of morbidity than blood lactate in terms of intensive care unit stay in patients undergoing off pump coronary artery bypass grafting.
