Conjugated linoleic acid (CLA) is a kind of fatty acid with physiological activities and potential application prospect. A synthesis method of conjugated linoleic acid and a purification technology were studied. CLA w...Conjugated linoleic acid (CLA) is a kind of fatty acid with physiological activities and potential application prospect. A synthesis method of conjugated linoleic acid and a purification technology were studied. CLA was prepared and purified by urea-complexation and conjugation using safflower oil as raw material. The purity of CLA and total recovery of the product was more than 95% and 48%, respectively. The main isomers produced in alkali-catalyzed conjugation were identified by gas chromatography (GC) linked to mass spectrometry (MS) and Fourier transform infrared spectroscopy (FTIR). The total amount of the two main isomers (9cis, 11trons-and 10trans, 12cis-CLA) determined by GC was more than 90% of the product.展开更多
油页岩的萃取物中含有多种脂肪烃、芳香烃和含N,O,S杂原子化合物,为了提高页岩油的利用价值,需要将混合物分离。通过萃取、尿素络合分离,柱层析分离等方法达到萃取物组分族分离的目的。在温和条件下对油页岩进行了甲醇溶剂萃取,对萃取...油页岩的萃取物中含有多种脂肪烃、芳香烃和含N,O,S杂原子化合物,为了提高页岩油的利用价值,需要将混合物分离。通过萃取、尿素络合分离,柱层析分离等方法达到萃取物组分族分离的目的。在温和条件下对油页岩进行了甲醇溶剂萃取,对萃取液原样采取尿素络合法,分离出了正构烷烃,并得到尿素络合法的分离工艺条件为:尿素质量13 g、乙醇体积30 m L、反应温度30℃、反应时间90 min。用硅胶柱色谱分离络合后的其他物质,分别采用正己烷、苯、甲醇3种不同淋洗液淋洗,得到10个组分的混合物。用正己烷淋洗的接收液为烷烃类;用苯淋洗的接收液中,含有苯环结构的化合物;用甲醇淋洗的接收液,含有醚类物质和氨基等杂原子化合物。展开更多
Nervonic acid is the world’s first and only potent substance that can repair damaged nerve fibers and promote nerve cell regeneration with high nutritional value.The wide variety of fatty acids in plant oils and fats...Nervonic acid is the world’s first and only potent substance that can repair damaged nerve fibers and promote nerve cell regeneration with high nutritional value.The wide variety of fatty acids in plant oils and fats with similar structures makes the large-scale separation and purification of high-purity nervonic acid very difficult.A new combined process of molecular distillation,urea inclusion and solvent crystallization was established to prepare high-purity nervonic acid with the mixed fatty acids obtained after saponification and acidification of Acer truncatum Bunge oil as raw materials.First,according to the difference in the mean free path of fatty acids,molecular distillation was used to separate and remove C16 saturated fatty acid of palmitic acid and four C18-C20 fatty acids of stearic,oleic,linoleic,and linolenic acids.The content of C16-C20 fatty acids decreased from 72.92% to 19.22% after two-stage molecular distillation processes,in which the contents of saturated fatty acid of palmitic acid decreased to about 0.5%.Then,according to the difference in carbon chain length and saturation of fatty acid,the contents of C22-C24 saturated fatty acids of tetracosanoic and docosanoic acids decreased to 0.21% and 0.07% by urea inclusion with urea/free fatty acid preparation by saponification(SPOMFs)ratio as 0.6.In addition,all saturated fatty acids were basically separated.Finally,according to the difference in the solubility of fatty acids in solvents,the C18-C20 unsaturated fatty acids of oleic,linoleic,and linolenic acids and C22 unsaturated fatty acid of erucic acid were removed by solvent crystallization.The content of C18-C20 unsaturated fatty acids decreased to less than 5% with pentanol as the solvent after the first stage solvent crystallization.The content of erucic acid decreased to 3.47% with anhydrous ethanol as the solvent after the second to fifth stage solvent crystallization.The combined process of molecular distillation,urea inclusion and low temperature crystallization innovatively adopt展开更多
<正> Urea can be sorbed by coordination （or complexation）with transitional metalpolyacrylic acid complex and transitional metal-polyacrylamide containing polyethylenepolyamine ligand complexes. The experimenta...<正> Urea can be sorbed by coordination （or complexation）with transitional metalpolyacrylic acid complex and transitional metal-polyacrylamide containing polyethylenepolyamine ligand complexes. The experimental results indicate that the sorbents can sorb about 60mg urea per gram of sorbent at 37℃ and the concentration of urea was 1300.0rag/1 in NaH2PO4and Na2HPO4buffer solution （pH=7.0） and the urea sorption capacity was affected by many factors such as other competive ligands, sorption time, pH and the concentration of urea.展开更多
文摘Conjugated linoleic acid (CLA) is a kind of fatty acid with physiological activities and potential application prospect. A synthesis method of conjugated linoleic acid and a purification technology were studied. CLA was prepared and purified by urea-complexation and conjugation using safflower oil as raw material. The purity of CLA and total recovery of the product was more than 95% and 48%, respectively. The main isomers produced in alkali-catalyzed conjugation were identified by gas chromatography (GC) linked to mass spectrometry (MS) and Fourier transform infrared spectroscopy (FTIR). The total amount of the two main isomers (9cis, 11trons-and 10trans, 12cis-CLA) determined by GC was more than 90% of the product.
文摘油页岩的萃取物中含有多种脂肪烃、芳香烃和含N,O,S杂原子化合物,为了提高页岩油的利用价值,需要将混合物分离。通过萃取、尿素络合分离,柱层析分离等方法达到萃取物组分族分离的目的。在温和条件下对油页岩进行了甲醇溶剂萃取,对萃取液原样采取尿素络合法,分离出了正构烷烃,并得到尿素络合法的分离工艺条件为:尿素质量13 g、乙醇体积30 m L、反应温度30℃、反应时间90 min。用硅胶柱色谱分离络合后的其他物质,分别采用正己烷、苯、甲醇3种不同淋洗液淋洗,得到10个组分的混合物。用正己烷淋洗的接收液为烷烃类;用苯淋洗的接收液中,含有苯环结构的化合物;用甲醇淋洗的接收液,含有醚类物质和氨基等杂原子化合物。
基金supported by the National Natural Science Foundation of China(22125802 and 22078010)Beijing Natural Science Foundation(2222017)Big Science Project from BUCT(XK180301).
文摘Nervonic acid is the world’s first and only potent substance that can repair damaged nerve fibers and promote nerve cell regeneration with high nutritional value.The wide variety of fatty acids in plant oils and fats with similar structures makes the large-scale separation and purification of high-purity nervonic acid very difficult.A new combined process of molecular distillation,urea inclusion and solvent crystallization was established to prepare high-purity nervonic acid with the mixed fatty acids obtained after saponification and acidification of Acer truncatum Bunge oil as raw materials.First,according to the difference in the mean free path of fatty acids,molecular distillation was used to separate and remove C16 saturated fatty acid of palmitic acid and four C18-C20 fatty acids of stearic,oleic,linoleic,and linolenic acids.The content of C16-C20 fatty acids decreased from 72.92% to 19.22% after two-stage molecular distillation processes,in which the contents of saturated fatty acid of palmitic acid decreased to about 0.5%.Then,according to the difference in carbon chain length and saturation of fatty acid,the contents of C22-C24 saturated fatty acids of tetracosanoic and docosanoic acids decreased to 0.21% and 0.07% by urea inclusion with urea/free fatty acid preparation by saponification(SPOMFs)ratio as 0.6.In addition,all saturated fatty acids were basically separated.Finally,according to the difference in the solubility of fatty acids in solvents,the C18-C20 unsaturated fatty acids of oleic,linoleic,and linolenic acids and C22 unsaturated fatty acid of erucic acid were removed by solvent crystallization.The content of C18-C20 unsaturated fatty acids decreased to less than 5% with pentanol as the solvent after the first stage solvent crystallization.The content of erucic acid decreased to 3.47% with anhydrous ethanol as the solvent after the second to fifth stage solvent crystallization.The combined process of molecular distillation,urea inclusion and low temperature crystallization innovatively adopt
文摘<正> Urea can be sorbed by coordination （or complexation）with transitional metalpolyacrylic acid complex and transitional metal-polyacrylamide containing polyethylenepolyamine ligand complexes. The experimental results indicate that the sorbents can sorb about 60mg urea per gram of sorbent at 37℃ and the concentration of urea was 1300.0rag/1 in NaH2PO4and Na2HPO4buffer solution （pH=7.0） and the urea sorption capacity was affected by many factors such as other competive ligands, sorption time, pH and the concentration of urea.
