Background:Virtual reality(VR)technology is increasingly used in stroke rehabilitation.This study aimed to investigate the effectiveness of using the glasses-free VR training to improve motor function of upper limb in...Background:Virtual reality(VR)technology is increasingly used in stroke rehabilitation.This study aimed to investigate the effectiveness of using the glasses-free VR training to improve motor function of upper limb in patients with stroke.Methods:Twelve patients with stroke were recruited to participate in the intervention of 3 weeks.At the baseline and post intervention,two times of evaluation including Fugl-Meyer upper-extremity scale(FMS-UE),transcranial magnetic stimulation(TMS)measurement and motion evaluation were performed.Results:No significant difference was observed between two groups at baseline evaluation.After the intervention,the FMS-UE scores presented a greater improvement in the VR group compared with the control group.TMS measurement showed that there was significant difference in cortex latency and central motor conduction time between two groups after the intervention,but no significant difference in the amplitude of motor event potential was observed.In addition,there was a significant correlation between game scores and FMS-UE scores.Conclusions:The novel glasses-free VR training was at least as effective as conventional occupational therapy in upper limb motor function,improving nerve conduction time and corticospinal excitability in patient with stroke.展开更多
Individuals with hemiplegia suffer from impaired arm movements that appear as a marked change in arm stiffness. A quantitative measure of arm stiffness would characterize rehabilitation therapy effectively, while litt...Individuals with hemiplegia suffer from impaired arm movements that appear as a marked change in arm stiffness. A quantitative measure of arm stiffness would characterize rehabilitation therapy effectively, while little mechanism is designed to implement the function. A symmetrical five-bar linkage consisting of two revolute joints and three prismatic joints is presented. Inverse kinematics and forward kinematics are obtained first. Then inverse singularities and direct singularities of the mechanism are gained. The global stiffness index is defined based on the results of kinematics analysis. Finally, optimal dimensional synthesis of the mechanism in terms of maximum stiffness is conducted by genetic algorithms. The calculation results show that with the length of both the two linkage a=830 mm, the interacting angle of the two guides 2δ=4.48 radian, and the maximum range of displacement of the two carriers dmax=940 mm, the mechanism achieves highest rigidity and its workspace is singularity-free, which covers the human left and right arm range of motion. The proposed novel mechanism featuring high rigidity and a singularity-free workspace can provide rehabilitation training, also solve the problem of quantitative measure of arm stiffness.展开更多
目的探讨上肢深静脉血栓(upper-extremity deep vein thrombosis,UEDVT)、下肢深静脉血栓(lower-extremity deep vein thrombosis,LEDVT)形成危险因素的差异,为其制定针对性的预防和治疗护理对策提供循证依据。方法采用病例对照研究方法...目的探讨上肢深静脉血栓(upper-extremity deep vein thrombosis,UEDVT)、下肢深静脉血栓(lower-extremity deep vein thrombosis,LEDVT)形成危险因素的差异,为其制定针对性的预防和治疗护理对策提供循证依据。方法采用病例对照研究方法,按照1:1:1的原则,以年龄和性别为匹配条件,选取本院2007年10月—2017年1月所有非静脉导管相关UEDVT、LEDVT患者以及非深静脉血栓(deep vein thrombosis,DVT)患者各82例,回顾性查阅患者相关病历资料,分析UEDVT与LEDVT患者危险因素。结果logistic回归分析结果:UEDVT与LEDVT不同的独立危险因素有肺癌、乳腺癌、起搏器植入、感染;LEDVT的独立危险因素有创伤、糖尿病;两者相同的独立危险因素有手术史、VTE家族史。在实验室检查方面,蛋白C或蛋白S、抗凝血酶Ⅲ、抗磷抗体缺乏LEDVT患者多于UEDVT患者,组间比较,差异具有统计学意义(均P<0.05)。结论UEDVT与LEDVT形成的危险因素,既存在着一定的差异,但也有相同之处,并且其发生发展与一些先天性的遗传因子缺乏相关。应针对性采取不同的预防策略。展开更多
基金This study was supported by National Natural Science Foundation of China(Nos.31771016,32071316,and 81971224)partly supported by Guangdong Basic and Applied Basic Research Foundation(No.2020A1515011356)+1 种基金Guangzhou Research Collaborative Innovation Projects(No.201907010034)the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(No.2020-JKCS005).
文摘Background:Virtual reality(VR)technology is increasingly used in stroke rehabilitation.This study aimed to investigate the effectiveness of using the glasses-free VR training to improve motor function of upper limb in patients with stroke.Methods:Twelve patients with stroke were recruited to participate in the intervention of 3 weeks.At the baseline and post intervention,two times of evaluation including Fugl-Meyer upper-extremity scale(FMS-UE),transcranial magnetic stimulation(TMS)measurement and motion evaluation were performed.Results:No significant difference was observed between two groups at baseline evaluation.After the intervention,the FMS-UE scores presented a greater improvement in the VR group compared with the control group.TMS measurement showed that there was significant difference in cortex latency and central motor conduction time between two groups after the intervention,but no significant difference in the amplitude of motor event potential was observed.In addition,there was a significant correlation between game scores and FMS-UE scores.Conclusions:The novel glasses-free VR training was at least as effective as conventional occupational therapy in upper limb motor function,improving nerve conduction time and corticospinal excitability in patient with stroke.
基金Supported by National Natural Science Foundation of China(Grant No U1304510)Development Foundation for Outstanding Young Teachers of Zhengzhou University,China(Grant No.1421321076)
文摘Individuals with hemiplegia suffer from impaired arm movements that appear as a marked change in arm stiffness. A quantitative measure of arm stiffness would characterize rehabilitation therapy effectively, while little mechanism is designed to implement the function. A symmetrical five-bar linkage consisting of two revolute joints and three prismatic joints is presented. Inverse kinematics and forward kinematics are obtained first. Then inverse singularities and direct singularities of the mechanism are gained. The global stiffness index is defined based on the results of kinematics analysis. Finally, optimal dimensional synthesis of the mechanism in terms of maximum stiffness is conducted by genetic algorithms. The calculation results show that with the length of both the two linkage a=830 mm, the interacting angle of the two guides 2δ=4.48 radian, and the maximum range of displacement of the two carriers dmax=940 mm, the mechanism achieves highest rigidity and its workspace is singularity-free, which covers the human left and right arm range of motion. The proposed novel mechanism featuring high rigidity and a singularity-free workspace can provide rehabilitation training, also solve the problem of quantitative measure of arm stiffness.
文摘目的探讨上肢深静脉血栓(upper-extremity deep vein thrombosis,UEDVT)、下肢深静脉血栓(lower-extremity deep vein thrombosis,LEDVT)形成危险因素的差异,为其制定针对性的预防和治疗护理对策提供循证依据。方法采用病例对照研究方法,按照1:1:1的原则,以年龄和性别为匹配条件,选取本院2007年10月—2017年1月所有非静脉导管相关UEDVT、LEDVT患者以及非深静脉血栓(deep vein thrombosis,DVT)患者各82例,回顾性查阅患者相关病历资料,分析UEDVT与LEDVT患者危险因素。结果logistic回归分析结果:UEDVT与LEDVT不同的独立危险因素有肺癌、乳腺癌、起搏器植入、感染;LEDVT的独立危险因素有创伤、糖尿病;两者相同的独立危险因素有手术史、VTE家族史。在实验室检查方面,蛋白C或蛋白S、抗凝血酶Ⅲ、抗磷抗体缺乏LEDVT患者多于UEDVT患者,组间比较,差异具有统计学意义(均P<0.05)。结论UEDVT与LEDVT形成的危险因素,既存在着一定的差异,但也有相同之处,并且其发生发展与一些先天性的遗传因子缺乏相关。应针对性采取不同的预防策略。
