This study aims to evaluate the torsional dynamics and 2D speckle tracking in heart failure with reduced ejection fraction on patients taking angiotensin receptor neprilysin inhibitors (ARNI) and none.?ARNI has been s...This study aims to evaluate the torsional dynamics and 2D speckle tracking in heart failure with reduced ejection fraction on patients taking angiotensin receptor neprilysin inhibitors (ARNI) and none.?ARNI has been shown to be superior to enalapril in?the?long term reducing the mortality and hospitalization of heart failure (HF). However short-term effects on diastolic function remain unclear. We sought to evaluate 6 months' effects of ARNI on left ventricular (LV) diastolic parameters determined by speckle tracking and tissue Doppler imaging. This study was carried out in Menoufia University Hospitals including 60 patients of HFrEF during the period from August 2019 to January 2020. (50%) of patients were?treated with traditional treatment of heart failure and the remaining were?treated with ARNI. Data were collected including history and clinical examination. ECG and speckle tracking and tissue Doppler imaging were?done to evaluate the diastolic function. Our results showed no significant difference between the two groups at baseline. There was?a?significant improvement?in?the LV diastolic function parameters. Untwisting?time and untwisting?onset showed the highly significant parameters of improvement. This study concluded that ARNI showed short term improvement of diastolic function of the left ventricle that could be detected by STE.展开更多
The twists of twelve kinds of the cotton OE yarns in different machine twists and different yarn linear density have been determined by one time back twisting and twisting method, triple twisting method and double twi...The twists of twelve kinds of the cotton OE yarns in different machine twists and different yarn linear density have been determined by one time back twisting and twisting method, triple twisting method and double twisting method. The quantitative analysis of the measurement principles of all the untwisting and retwisting methods has been made by the writers. It is theoretically and practically concluded that for twelve kinds of the cotton OE yarns the difference between the twist determined by triple twisting method and machine twist is the lowest and there is measuring method error in determining the twist of OE yarn by all the untwisting and retwisting methods.展开更多
Metal ions play important roles in the biological functions of nucleic adds. It is of importance to the life sciences to investigate the reaction of nucleic acids with metal ions. In the note the interaction of double...Metal ions play important roles in the biological functions of nucleic adds. It is of importance to the life sciences to investigate the reaction of nucleic acids with metal ions. In the note the interaction of double-stranded helical structure nucleic acid, polyinosinic acid: polycytidylic acid （poly （I:C）） with Cu<sup>2+</sup> is studied by means of absorption spectra, circular dichroism, fluorescent spectra, melting and cooling curves, acid titration curves and ethidium bromide fluorescent probe. The results show that Cu<sup>2+</sup> breaks the hydrogen-bonded structure of poly （I: C）, and the poly （I: C） untwisting induced by Cu<sup>2+</sup> is un-reversible and the apparent binding constant of poly （I: C） with Cu<sup>2+</sup> is 1.23×10<sup>4</sup>展开更多
Twist structures have diverse applications, ranging from dragline, electrical cable, and intelligent structure. Among these applications, tension deformation can＇t be avoided during the fabrication and working proces...Twist structures have diverse applications, ranging from dragline, electrical cable, and intelligent structure. Among these applications, tension deformation can＇t be avoided during the fabrication and working processes, which often leads to the twist structure rotation （called untwisting effect） and twist pitch increasing. As a consequence, this untwisting behavior has a large effect on the effective Young＇s modulus. In this paper, we present an improved model based on the classical Costello＇s theory to predict the effective Young＇s modulus of the basic structure, twisted by three same copper strands under cyclic loading. Series of experiments were carried out to verify the present model taking into account the untwisting effect. The experimental results have better agreements with the presented model than the common Costello＇s model.展开更多
文摘This study aims to evaluate the torsional dynamics and 2D speckle tracking in heart failure with reduced ejection fraction on patients taking angiotensin receptor neprilysin inhibitors (ARNI) and none.?ARNI has been shown to be superior to enalapril in?the?long term reducing the mortality and hospitalization of heart failure (HF). However short-term effects on diastolic function remain unclear. We sought to evaluate 6 months' effects of ARNI on left ventricular (LV) diastolic parameters determined by speckle tracking and tissue Doppler imaging. This study was carried out in Menoufia University Hospitals including 60 patients of HFrEF during the period from August 2019 to January 2020. (50%) of patients were?treated with traditional treatment of heart failure and the remaining were?treated with ARNI. Data were collected including history and clinical examination. ECG and speckle tracking and tissue Doppler imaging were?done to evaluate the diastolic function. Our results showed no significant difference between the two groups at baseline. There was?a?significant improvement?in?the LV diastolic function parameters. Untwisting?time and untwisting?onset showed the highly significant parameters of improvement. This study concluded that ARNI showed short term improvement of diastolic function of the left ventricle that could be detected by STE.
文摘The twists of twelve kinds of the cotton OE yarns in different machine twists and different yarn linear density have been determined by one time back twisting and twisting method, triple twisting method and double twisting method. The quantitative analysis of the measurement principles of all the untwisting and retwisting methods has been made by the writers. It is theoretically and practically concluded that for twelve kinds of the cotton OE yarns the difference between the twist determined by triple twisting method and machine twist is the lowest and there is measuring method error in determining the twist of OE yarn by all the untwisting and retwisting methods.
基金Project supported by the National Natural Science Foundation of China.
文摘Metal ions play important roles in the biological functions of nucleic adds. It is of importance to the life sciences to investigate the reaction of nucleic acids with metal ions. In the note the interaction of double-stranded helical structure nucleic acid, polyinosinic acid: polycytidylic acid （poly （I:C）） with Cu<sup>2+</sup> is studied by means of absorption spectra, circular dichroism, fluorescent spectra, melting and cooling curves, acid titration curves and ethidium bromide fluorescent probe. The results show that Cu<sup>2+</sup> breaks the hydrogen-bonded structure of poly （I: C）, and the poly （I: C） untwisting induced by Cu<sup>2+</sup> is un-reversible and the apparent binding constant of poly （I: C） with Cu<sup>2+</sup> is 1.23×10<sup>4</sup>
基金supported by the National Natural Science Foundation of China(11622217)the National Key Project of Scientific Instrument and Equipment Development(11327802)+1 种基金the National Program for Special Support of Top-Notch Young Professionalssupported by the Fundamental Research Funds for the Central Universities(lzujbky-2017-ot18,lzujbky-2017-k18)
文摘Twist structures have diverse applications, ranging from dragline, electrical cable, and intelligent structure. Among these applications, tension deformation can＇t be avoided during the fabrication and working processes, which often leads to the twist structure rotation （called untwisting effect） and twist pitch increasing. As a consequence, this untwisting behavior has a large effect on the effective Young＇s modulus. In this paper, we present an improved model based on the classical Costello＇s theory to predict the effective Young＇s modulus of the basic structure, twisted by three same copper strands under cyclic loading. Series of experiments were carried out to verify the present model taking into account the untwisting effect. The experimental results have better agreements with the presented model than the common Costello＇s model.
