We studied the effect of all-trans-retinoic acid (RA)on the expression of several surface lectin receptors and cell membrane fluidity of mouse forestomach carcinoma cell line (MFC) in vitro. The results showed that ce...We studied the effect of all-trans-retinoic acid (RA)on the expression of several surface lectin receptors and cell membrane fluidity of mouse forestomach carcinoma cell line (MFC) in vitro. The results showed that cells treated with RA manifested decreased expression of lectin receptors, increased memhrane fluidity and reduced spontaneous metastasis. These results suggest that the effect of RA on tumor cell membrane may be one of the mechanisms involved in the alternation of cell metastatic phenotype.展开更多
Quenching effects of cis-DDP on fluorescence of membranes of rat Ehrlich ascites tumor cell and binding of cis-DDP with the membranes were studied.The results indicate that cis-DDP can react with tumor cell membrane p...Quenching effects of cis-DDP on fluorescence of membranes of rat Ehrlich ascites tumor cell and binding of cis-DDP with the membranes were studied.The results indicate that cis-DDP can react with tumor cell membrane proteins.If the Pt binding sites were grouped into two types,the apparent stability canstants(K) and number of binding sites(n) are estimated.展开更多
文摘We studied the effect of all-trans-retinoic acid (RA)on the expression of several surface lectin receptors and cell membrane fluidity of mouse forestomach carcinoma cell line (MFC) in vitro. The results showed that cells treated with RA manifested decreased expression of lectin receptors, increased memhrane fluidity and reduced spontaneous metastasis. These results suggest that the effect of RA on tumor cell membrane may be one of the mechanisms involved in the alternation of cell metastatic phenotype.
文摘Quenching effects of cis-DDP on fluorescence of membranes of rat Ehrlich ascites tumor cell and binding of cis-DDP with the membranes were studied.The results indicate that cis-DDP can react with tumor cell membrane proteins.If the Pt binding sites were grouped into two types,the apparent stability canstants(K) and number of binding sites(n) are estimated.