In January 2013, a long-lasting episode of severe haze occurred in central and eastern China, and it attracted attention from all sectors of society. The process and evolution of haze pollution episodes were observed ...In January 2013, a long-lasting episode of severe haze occurred in central and eastern China, and it attracted attention from all sectors of society. The process and evolution of haze pollution episodes were observed by the ＂Forming Mechanism and Con- trol Strategies of Haze in China＂ group using an intensive aerosol and trace gases campaign that simultaneously obtained data at 11 ground-based observing sites in the CARE-China network. The characteristics and formation mechanism of haze pollu- tion episodes were discussed. Five haze pollution episodes were identified in the Beijing-Tianjin-Hebei （Jing-Jin-Ji） area; the two most severe episodes occurred during 9-15 January and 25-31 January. During these two haze pollution episodes, the maximum hourly PMz5 mass concentrations in Beijing were 680 and 530 ~tg m-3, respectively. The process and evolution of haze pollution episodes in other major cities in the Jing-Jin-Ji area, such as Shijiazhuang and Tianjin were almost the same as those observed in Beijing. The external cause of the severe haze episodes was the unusual atmospheric circulation, the depres- sion of strong cold air activities and the very unfavorable dispersion due to geographical and meteorological conditions. How- ever, the internal cause was the quick secondary transformation of primary gaseous pollutants to secondary aerosols, which contributed to the ＂explosive growth＂ and ＂sustained growth＂ of PM2.5. Particularly, the abnormally high amount of nitric ox- ide （NOx） in the haze episodes, produced by fossil fuel combustion and vehicle emissions, played a direct or indirect role in the quick secondary transformation of coal-burning sulphur dioxide （SO2） to sulphate aerosols. Furthermore, gaseous pollutants were transformed into secondary aerosols through heterogeneous reactions on the surface of fine particles, which can change the particle＇s size and chemical composition. Consequently, the proportion of secondary inorganic ions, such as sulphate and nitrate, gradually incr展开更多
The implementation of new type industrialization and urbanization and agricultural modernization strategies lacks of a major hand grip and spatial supporting platform, due to long-term existed ＂dual-track＂ structure...The implementation of new type industrialization and urbanization and agricultural modernization strategies lacks of a major hand grip and spatial supporting platform, due to long-term existed ＂dual-track＂ structure of rural-urban development in China as well as un- stable rural development institution and mechanism. It is necessary to restructure rural pro- duction, living and ecological space by carrying out land consolidation, so as to establish a new platform for building new countryside and realizing urban-rural integration development in China. This paper develops the concept and connotation of rural spatial restructuring. Basing on the effects analysis of industrialization and urbanization on rural production, living and ecological space, the mechanism of pushing forward rural spatial restructuring by carry- ing out land consolidation is probed. A conceptualization of the models of rural production, living and ecological spatial restructuring is analyzed combining with agricultural land con- solidation, hollowed villages consolidation and industrial and mining land consolidation. Fi- nally, the author argues that a ＂bottom-up＂ restructuring strategy accompanied by a few ＂top-down＂ elements is helpful for smoothly pushing forward rural spatial restructuring in China. In addition, the optimization and restructuring of rural production, living and ecological space will rely on the innovations of regional engineering technology, policy and mechanism, and mode of rural land consolidation, and more attentions should be paid to rural space, the foundation base and platform for realizing urban-rural integration development.展开更多
The transition of the global atmospheric circulation in the end of 1970's can clearly be detected in the atmospheric temperature, wind velocity, and so on. Wavelet analysis reveals that the temporal scale of this ...The transition of the global atmospheric circulation in the end of 1970's can clearly be detected in the atmospheric temperature, wind velocity, and so on. Wavelet analysis reveals that the temporal scale of this change is larger than 20 years. Studies in this work indicate that the trend of the transition over the mid-latitude Asia is opposite to that of global average for some variables at the middle troposphere. Another finding of this research is that the African-Asian monsoon circulation is weaker and the trade wind over the tropical eastern Pacific is weaker as well after this transition. Such a signal may be found in the summer precipitation over China as well. Key words Asian monsoon circulation - Weakening - Transition This research was supported by the key project of Chinese Academy of Sciences under Contract KZCX2-203 and the key program of the National Natural Science Foundation of China under Contract 49894170.展开更多
The cell-biological program termed the epithelial-to-mesenchymal transition （EMT） plays an important role in both development and cancer progression. Depending on the contextual signals and intracellular gene circui...The cell-biological program termed the epithelial-to-mesenchymal transition （EMT） plays an important role in both development and cancer progression. Depending on the contextual signals and intracellular gene circuits of a particular cell, this program can drive fully epithelial cells to enter into a series of phenotypic states arrayed along the epithelial-mesenehymal phenotypic axis. These cell states display distinctive cellular characteristics, including stemness, invasiveness, drug-resistance and the ability to form metastases at distant organs, and thereby contribute to cancer metastasis and relapse. Currently we still lack a coherent overview of the molecular and biochemical mechanisms inducing cells to enter various states along the epithelial-mesenchymal phenotypic spectrum. An improved understanding of the dynamic and plastic nature of the EMT program has the potential to yield novel therapies targeting this cellular program that may aid in the management of high-grade malignancies.展开更多
基金supported by the Chinese Academy of Sciences Strategic Priority Research Program(Grant Nos.XDB05020000 and XDA05100100)the National Natural Science Foundation of China(Grant Nos.41230642 and 41021004)
文摘In January 2013, a long-lasting episode of severe haze occurred in central and eastern China, and it attracted attention from all sectors of society. The process and evolution of haze pollution episodes were observed by the ＂Forming Mechanism and Con- trol Strategies of Haze in China＂ group using an intensive aerosol and trace gases campaign that simultaneously obtained data at 11 ground-based observing sites in the CARE-China network. The characteristics and formation mechanism of haze pollu- tion episodes were discussed. Five haze pollution episodes were identified in the Beijing-Tianjin-Hebei （Jing-Jin-Ji） area; the two most severe episodes occurred during 9-15 January and 25-31 January. During these two haze pollution episodes, the maximum hourly PMz5 mass concentrations in Beijing were 680 and 530 ~tg m-3, respectively. The process and evolution of haze pollution episodes in other major cities in the Jing-Jin-Ji area, such as Shijiazhuang and Tianjin were almost the same as those observed in Beijing. The external cause of the severe haze episodes was the unusual atmospheric circulation, the depres- sion of strong cold air activities and the very unfavorable dispersion due to geographical and meteorological conditions. How- ever, the internal cause was the quick secondary transformation of primary gaseous pollutants to secondary aerosols, which contributed to the ＂explosive growth＂ and ＂sustained growth＂ of PM2.5. Particularly, the abnormally high amount of nitric ox- ide （NOx） in the haze episodes, produced by fossil fuel combustion and vehicle emissions, played a direct or indirect role in the quick secondary transformation of coal-burning sulphur dioxide （SO2） to sulphate aerosols. Furthermore, gaseous pollutants were transformed into secondary aerosols through heterogeneous reactions on the surface of fine particles, which can change the particle＇s size and chemical composition. Consequently, the proportion of secondary inorganic ions, such as sulphate and nitrate, gradually incr
基金National Natural Science Foundation of China,No.41171149No.41130748No.41201176
文摘The implementation of new type industrialization and urbanization and agricultural modernization strategies lacks of a major hand grip and spatial supporting platform, due to long-term existed ＂dual-track＂ structure of rural-urban development in China as well as un- stable rural development institution and mechanism. It is necessary to restructure rural pro- duction, living and ecological space by carrying out land consolidation, so as to establish a new platform for building new countryside and realizing urban-rural integration development in China. This paper develops the concept and connotation of rural spatial restructuring. Basing on the effects analysis of industrialization and urbanization on rural production, living and ecological space, the mechanism of pushing forward rural spatial restructuring by carry- ing out land consolidation is probed. A conceptualization of the models of rural production, living and ecological spatial restructuring is analyzed combining with agricultural land con- solidation, hollowed villages consolidation and industrial and mining land consolidation. Fi- nally, the author argues that a ＂bottom-up＂ restructuring strategy accompanied by a few ＂top-down＂ elements is helpful for smoothly pushing forward rural spatial restructuring in China. In addition, the optimization and restructuring of rural production, living and ecological space will rely on the innovations of regional engineering technology, policy and mechanism, and mode of rural land consolidation, and more attentions should be paid to rural space, the foundation base and platform for realizing urban-rural integration development.
基金the key project of Chinese Academy of Sciences under ContractKZCX2-203 and the key program of the National Natural Science Fou
文摘The transition of the global atmospheric circulation in the end of 1970's can clearly be detected in the atmospheric temperature, wind velocity, and so on. Wavelet analysis reveals that the temporal scale of this change is larger than 20 years. Studies in this work indicate that the trend of the transition over the mid-latitude Asia is opposite to that of global average for some variables at the middle troposphere. Another finding of this research is that the African-Asian monsoon circulation is weaker and the trade wind over the tropical eastern Pacific is weaker as well after this transition. Such a signal may be found in the summer precipitation over China as well. Key words Asian monsoon circulation - Weakening - Transition This research was supported by the key project of Chinese Academy of Sciences under Contract KZCX2-203 and the key program of the National Natural Science Foundation of China under Contract 49894170.
文摘The cell-biological program termed the epithelial-to-mesenchymal transition （EMT） plays an important role in both development and cancer progression. Depending on the contextual signals and intracellular gene circuits of a particular cell, this program can drive fully epithelial cells to enter into a series of phenotypic states arrayed along the epithelial-mesenehymal phenotypic axis. These cell states display distinctive cellular characteristics, including stemness, invasiveness, drug-resistance and the ability to form metastases at distant organs, and thereby contribute to cancer metastasis and relapse. Currently we still lack a coherent overview of the molecular and biochemical mechanisms inducing cells to enter various states along the epithelial-mesenchymal phenotypic spectrum. An improved understanding of the dynamic and plastic nature of the EMT program has the potential to yield novel therapies targeting this cellular program that may aid in the management of high-grade malignancies.
