Effects of tranquil and its inhalation toxicity in experimental animals were studied. The drug was administered to the mice through respiratory tract by a static intoxication equipment. Automatic activities (AA) of mi...Effects of tranquil and its inhalation toxicity in experimental animals were studied. The drug was administered to the mice through respiratory tract by a static intoxication equipment. Automatic activities (AA) of mice were recorded by a YSD4G pharmacologicalphysiological multitrack recording equipment to evaluate the combined effects of tranquil and pentobarbital. Changes in amount of cerebral 5hydroxytryptamine(5HT) and 5hydroxyindole acetic acid (5HIAA) were observed. The results showed that tranquil could reduce the AA of mice and exert a synergic hypnotic effect with pentobarbital. There was a tendency in decreasing cerebral 5HT and increasing 5HIAA. LC50 value for mice exceeded 70 000 mg/m\+3. In rats exposed to tranquil at 59 066 mg/m\+3, 4 hours every day for 3 consecutive days, Author no respiratory irritative action was observed. This indicated the inhibitory effects of tranquil on the CNS of mice. Its action mechanism is probably different from that of diazepam and may be related to the function of central neurotransmitter 5hydroxytryptamine. Tranquil has low inhalation toxicity and no irritative action on the respiratory tract.\;展开更多
The main oil-bearing formation of Area 4 of Tahe oilfield is in Yingshan Group of Ordovician consisted of thick pure limestone. The types of the pore space contain the pore, fissure, cave as well as fracture formed by...The main oil-bearing formation of Area 4 of Tahe oilfield is in Yingshan Group of Ordovician consisted of thick pure limestone. The types of the pore space contain the pore, fissure, cave as well as fracture formed by solution collapse. The primary porosity and tectonic fracture are of poor growth. Therefore, the formation growth is mainly controlled by hydraulic units of the palaeo-karst. There are three palaeo-hydraulic zones: vadose zone (including infiltration sub-zone and percolation sub-zone), phreatic zone and tranquil zone. They are identified by retrieving the palaeo-geographical karst environment. The pore space of the infiltration zone is mainly solution fissures, small solution cavities and solution pores. The growth and lateral connection of the formation are favorable. The reservoir/formation ratio is 0. 54. The pore space of the phreatic zone developed large size cavities and fractures related to cave collapse. The height of the cavity can reach 71m. The fractures by collapse have a influencing range of more than 100m, and its reservoir/formation ratio is 0. 51. But the lateral connection is unfavorable. The percolation subzone and the tranquil zone are of relatively poor growth with the reservoir/ formation ratio less than 0. 3.展开更多
文摘Effects of tranquil and its inhalation toxicity in experimental animals were studied. The drug was administered to the mice through respiratory tract by a static intoxication equipment. Automatic activities (AA) of mice were recorded by a YSD4G pharmacologicalphysiological multitrack recording equipment to evaluate the combined effects of tranquil and pentobarbital. Changes in amount of cerebral 5hydroxytryptamine(5HT) and 5hydroxyindole acetic acid (5HIAA) were observed. The results showed that tranquil could reduce the AA of mice and exert a synergic hypnotic effect with pentobarbital. There was a tendency in decreasing cerebral 5HT and increasing 5HIAA. LC50 value for mice exceeded 70 000 mg/m\+3. In rats exposed to tranquil at 59 066 mg/m\+3, 4 hours every day for 3 consecutive days, Author no respiratory irritative action was observed. This indicated the inhibitory effects of tranquil on the CNS of mice. Its action mechanism is probably different from that of diazepam and may be related to the function of central neurotransmitter 5hydroxytryptamine. Tranquil has low inhalation toxicity and no irritative action on the respiratory tract.\;
文摘The main oil-bearing formation of Area 4 of Tahe oilfield is in Yingshan Group of Ordovician consisted of thick pure limestone. The types of the pore space contain the pore, fissure, cave as well as fracture formed by solution collapse. The primary porosity and tectonic fracture are of poor growth. Therefore, the formation growth is mainly controlled by hydraulic units of the palaeo-karst. There are three palaeo-hydraulic zones: vadose zone (including infiltration sub-zone and percolation sub-zone), phreatic zone and tranquil zone. They are identified by retrieving the palaeo-geographical karst environment. The pore space of the infiltration zone is mainly solution fissures, small solution cavities and solution pores. The growth and lateral connection of the formation are favorable. The reservoir/formation ratio is 0. 54. The pore space of the phreatic zone developed large size cavities and fractures related to cave collapse. The height of the cavity can reach 71m. The fractures by collapse have a influencing range of more than 100m, and its reservoir/formation ratio is 0. 51. But the lateral connection is unfavorable. The percolation subzone and the tranquil zone are of relatively poor growth with the reservoir/ formation ratio less than 0. 3.
