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产前筛查并染色体分析预防染色体病胎儿出生 被引量:2
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作者 王宏 陈武斌 《中国妇幼健康研究》 2011年第4期511-514,共4页
目的对产前筛查和染色体分析预防染色体病胎儿出生的工作进行回顾性的总结,为今后减少出生缺陷提供指导。方法通过对优生咨询、血清筛查检出的高风险孕妇和超声筛查怀疑胎儿有染色体病的孕妇进行胎儿染色体分析,核型严重异常者终止妊... 目的对产前筛查和染色体分析预防染色体病胎儿出生的工作进行回顾性的总结,为今后减少出生缺陷提供指导。方法通过对优生咨询、血清筛查检出的高风险孕妇和超声筛查怀疑胎儿有染色体病的孕妇进行胎儿染色体分析,核型严重异常者终止妊娠。结果①优生咨询筛查出的高风险孕妇中接受染色体分析者372例,染色体异常检出率为4.57%(17/372),终止妊娠5例;②血清筛查孕妇共32848例,高风险2085例,筛查阳性率6.35%;染色体分析740例,染色体异常检出率为4.59%(34/740),终止妊娠18例;③超声筛查异常进行染色体分析177例,异常检出率为19.77%(35/177),终止妊娠32例;④染色体分析共1289例,异常检出率为6.67%(86/1289),数目异常50例全部终止妊娠,结构异常36例中有5例终止妊娠,终止妊娠率为4.27%(55/1289)。结论优生咨询、血清筛查、超声筛查组成的筛查体系结合染色体分析可提高染色体病的检出率,超声筛查的检出率最高;每位孕妇都应接受系统的产前筛查,高危孕妇应接受染色体分析,最大限度地避免染色体病胎儿出生。 展开更多
关键词 产前筛查 高危孕妇 染色体异常 终止妊娠
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Evaluation of Current Termination of Pregnancy and Related Services at Grimsby(UK) and Recommendations for Service Improvement
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作者 Ka Yan Shirley SZE Ibrahim BOLAJI 《Journal of Reproduction and Contraception》 CAS 2013年第3期181-193,共13页
Objective To develop local termination of pregnancy (TOP) dataset and to identify "hotspots" for highest activity and gaps in our fertility control services. Methods This was a retrospective analysis of 305 women... Objective To develop local termination of pregnancy (TOP) dataset and to identify "hotspots" for highest activity and gaps in our fertility control services. Methods This was a retrospective analysis of 305 women who received TOP under section C of the Abortion Act 1967 over a period of 9 consecutive months from 1st March through to 31st October 2012. Results There were 275 (90.2%) British White (BW) and 30 non-BW women. Among 30 non-BW women, 10 (3.3%) were British Asian, 8 (2.6%) were Polish, 6 (2.0%) were British Black or Black, 5 (1.6%) were Chinese and i (0.3%) was White Latvian. The TOP rate was 8.9% in the under 18 years old and 27.9% in the over 30 years old. Totally 240 TOPs (78. 7%) occurred in 〈10 weeks and 276 TOPs (90.5%) occurred under 13 weeks of gestation. Eight-five women who received TOP-service have had one or more previous termination(s) in the last 3 years. The contraception use was low pre-TOP and none of the women were on long-acting reversible contraception (LARCs) pre- TOP, including those who had repeat terminations. Conclusion There are inequalities and gaps in the TOP and related services in Grimsby which must be addressed to reduce the rate of TOP. This is a major challenge involving multiple agencies. Provision of contraception across all age and ethnic groups, improving sex education, engaging with parents and women to improve their negotiation skills for safer sex, supporting vulnerable women, reducing risk factors e.g. alcohol and substance misuse and raising aspirations across the region will contribute to a reduction in termination rate. 展开更多
关键词 termination of pregnancy top CONTRACEPTION long acting reversible contraception (LARC)
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Prenatal congenital heart defects in southern China:detection rate and termination of preqnancy,2006-2016
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作者 Yongchao Yang Yu Xia +4 位作者 Shufang Huang Yueheng Wu Jimei Chen Ping Li Jian Zhuang 《中国循环杂志》 CSCD 北大核心 2018年第S01期114-114,共1页
Objective Congenital heart defect (CHD) is one of the most common birth anomalies with high morbidity and mortality. Previous studies of CHD mostly focus on the postnatal prevalence, mortality and successful rate of o... Objective Congenital heart defect (CHD) is one of the most common birth anomalies with high morbidity and mortality. Previous studies of CHD mostly focus on the postnatal prevalence, mortality and successful rate of operation, etc. This study aimed to explore the detection rate of prenatal CHD and CHD factors that attribute to termination of pregnancy (TOP). 展开更多
关键词 CONGENITAL heart defect(CHD) POSTNATAL prevalence termination of pregnancy(top)
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