Web服务作为一种新型的Web应用模式,近年来得到了迅速的发展.如何动态地把现存的各种Web服务整合起来以形成新的、满足不同用户需求的、增值的复杂服务已成为新的应用需求和研究热点.针对现有服务聚合中服务选择技术的不足,提出了一种...Web服务作为一种新型的Web应用模式,近年来得到了迅速的发展.如何动态地把现存的各种Web服务整合起来以形成新的、满足不同用户需求的、增值的复杂服务已成为新的应用需求和研究热点.针对现有服务聚合中服务选择技术的不足,提出了一种解决服务聚合中服务动态选择QoS全局最优化问题的实现算法GODSS(global optimal of dynamic Web services selection).算法的主要思想是把服务动态选择全局最优化问题转化为一个带QoS约束的多目标服务组合优化问题,利用多目标遗传算法的智能优化原理,通过同时优化多个目标函数,最终产生一组满足约束条件的Pareto优化服务聚合流程集.理论分析和实验结果说明了算法的可行性和有效性.展开更多
KaKs_Calculator is a software package that calculates nonsynonymous (Ka) and synonymous (Ks) substitution rates through model selection and model averaging. Since existing methods for this estimation adopt their s...KaKs_Calculator is a software package that calculates nonsynonymous (Ka) and synonymous (Ks) substitution rates through model selection and model averaging. Since existing methods for this estimation adopt their specific mutation (substitution) models that consider different evolutionary features, leading to diverse estimates, KaKs_Calculator implements a set of candidate models in a maximum likelihood framework and adopts the Akaike information criterion to measure fitness between models and data, aiming to include as many features as needed for accurately capturing evolutionary information in protein-coding sequences. In addition, several existing methods for calculating Ka and Ks are also incorporated into this software. KaKs_Calculator, including source codes, compiled executables, and documentation, is freely available for academic use at http://evolution.genomics.org.cn/software.htm.展开更多
基金Supported by the National HighTech Research and Development Plan of China under Grant Nos.2002AA1340102002AA1340202003AA135110(国家高技术研究发展计划(863))
文摘Web服务作为一种新型的Web应用模式,近年来得到了迅速的发展.如何动态地把现存的各种Web服务整合起来以形成新的、满足不同用户需求的、增值的复杂服务已成为新的应用需求和研究热点.针对现有服务聚合中服务选择技术的不足,提出了一种解决服务聚合中服务动态选择QoS全局最优化问题的实现算法GODSS(global optimal of dynamic Web services selection).算法的主要思想是把服务动态选择全局最优化问题转化为一个带QoS约束的多目标服务组合优化问题,利用多目标遗传算法的智能优化原理,通过同时优化多个目标函数,最终产生一组满足约束条件的Pareto优化服务聚合流程集.理论分析和实验结果说明了算法的可行性和有效性.
基金grants from the Ministry of Science and Technology of China (No. 2001AA231061) the National Natural Science Foundation of China (No. 30270748)
文摘KaKs_Calculator is a software package that calculates nonsynonymous (Ka) and synonymous (Ks) substitution rates through model selection and model averaging. Since existing methods for this estimation adopt their specific mutation (substitution) models that consider different evolutionary features, leading to diverse estimates, KaKs_Calculator implements a set of candidate models in a maximum likelihood framework and adopts the Akaike information criterion to measure fitness between models and data, aiming to include as many features as needed for accurately capturing evolutionary information in protein-coding sequences. In addition, several existing methods for calculating Ka and Ks are also incorporated into this software. KaKs_Calculator, including source codes, compiled executables, and documentation, is freely available for academic use at http://evolution.genomics.org.cn/software.htm.