本研究采用同体对照的方法,随机把12只大耳白兔分成5组。兔的左侧下颌体切除后缺损处用脱蛋白猪骨移植,右侧下颌骨体切除后骨缺损区用自体下颌骨移植。术后2、4、8、16、24周各处死兔子2只,进行 X 线照片和组织学观察。发现两种骨移植...本研究采用同体对照的方法,随机把12只大耳白兔分成5组。兔的左侧下颌体切除后缺损处用脱蛋白猪骨移植,右侧下颌骨体切除后骨缺损区用自体下颌骨移植。术后2、4、8、16、24周各处死兔子2只,进行 X 线照片和组织学观察。发现两种骨移植材料的骨修复过程相似。临床上可试用脱蛋白猪骨作为支架性骨移植材料替代自体骨移植。本实验为临床应用提供了初步的理论依据。展开更多
A pin-on-disk tribometer was used, in a comparative test to observe the tribological behavior of the swine femoral bone against UHMWPE with dry friction, physiological water and human plasma lubrication. The wear mech...A pin-on-disk tribometer was used, in a comparative test to observe the tribological behavior of the swine femoral bone against UHMWPE with dry friction, physiological water and human plasma lubrication. The wear mechanisms of swine bones and UHMWPE were investigated by SEM. The experimental results of these wear tests demon- strated that both the friction coefficient and wear rate of UHMWPE were the lowest when human plasma lubrication was used. The wear mechanism of the compact bone was mainly fatigue wear with dry friction, corrosive wear under physiological water lubrication and abrasive wear with human plasma lubrication. For UHMWPE, the wear mecha- nism was adhesive wear and plastic deformation with dry friction, serious ploughing and fatigue fracture wear under physiological water lubrication, fine ploughing and plastic deformation with human plasma lubrication. An analysis of nitrogen elements on the wear surface of UHMWPE indicated that the content of nitrogen in worn areas was 16 times higher than that in unworn areas, which proved that serum protein deposition occurred on worn areas.展开更多
文摘本研究采用同体对照的方法,随机把12只大耳白兔分成5组。兔的左侧下颌体切除后缺损处用脱蛋白猪骨移植,右侧下颌骨体切除后骨缺损区用自体下颌骨移植。术后2、4、8、16、24周各处死兔子2只,进行 X 线照片和组织学观察。发现两种骨移植材料的骨修复过程相似。临床上可试用脱蛋白猪骨作为支架性骨移植材料替代自体骨移植。本实验为临床应用提供了初步的理论依据。
基金Projects BK2005019 supported by the Natural Science Foundation of Jiangsu Province of China and 2005B032the Scientific Research Foundation ofChina University of Mining & Technology
文摘A pin-on-disk tribometer was used, in a comparative test to observe the tribological behavior of the swine femoral bone against UHMWPE with dry friction, physiological water and human plasma lubrication. The wear mechanisms of swine bones and UHMWPE were investigated by SEM. The experimental results of these wear tests demon- strated that both the friction coefficient and wear rate of UHMWPE were the lowest when human plasma lubrication was used. The wear mechanism of the compact bone was mainly fatigue wear with dry friction, corrosive wear under physiological water lubrication and abrasive wear with human plasma lubrication. For UHMWPE, the wear mecha- nism was adhesive wear and plastic deformation with dry friction, serious ploughing and fatigue fracture wear under physiological water lubrication, fine ploughing and plastic deformation with human plasma lubrication. An analysis of nitrogen elements on the wear surface of UHMWPE indicated that the content of nitrogen in worn areas was 16 times higher than that in unworn areas, which proved that serum protein deposition occurred on worn areas.
