As compared with the control,the malondialdehyde(MDA)levels in the cardi-ac,pulmonary,and intestinal tissues were elevated(P【0.05),and the superoxide dismu-tase activities in the cardiac,pulmonary,and intestinal tiss...As compared with the control,the malondialdehyde(MDA)levels in the cardi-ac,pulmonary,and intestinal tissues were elevated(P【0.05),and the superoxide dismu-tase activities in the cardiac,pulmonary,and intestinal tissues increased(P【0.05)at the30th min after endotoxic shock;the former in the cardiac,hepatic,renal,pulmonary,andintestinal tissues were elevated(P【0.05～0.001)and the latter in the cardiac,pulmona-ry,and intestinal tissues decreased in the 2nd h after shock;and the former were marke-dly elevated(P【0.01～0.001)and the latter severely decreased(P【【0.05～0.001)in allthe visceral tissues tested in the 4th h after shock.These data showed that lipid peroxid-ation mediated through oxygen-derived free radicals brought about tissue damage of theviscera listed above,which occurred earlier in the heart,the lungs and the intestines thanin the liver and the kidneys,and superoxide dismutase(SOD)activity was suppressed inthe late stage of endotoxic shock.展开更多
[Objective] To investigate the relationship between perinatal diseases and contents of superoxide dismutase （SOD） and malondialde- hyde （MDA） in serum of dairy cows. [ Method] A total of 38 dairy cows including 22...[Objective] To investigate the relationship between perinatal diseases and contents of superoxide dismutase （SOD） and malondialde- hyde （MDA） in serum of dairy cows. [ Method] A total of 38 dairy cows including 22 healthy cows, five cows with ketosis, four cows with fatty liver and seven cows with retained fatal placenta in perinatal period were selected. The contents of SOD and MDA in serum were respectively determined at different times ante partum and post partum. [Result] In the dairy cows with perinatal diseases, the SOD activity is lower and the MDA content was higher than that in the healthy dairy cows during perinatal period. [Conclusion] The antioxidant activity of dairy cows with perinatal diseases is lower than that of healthy dairy cows during perinatal period.展开更多
基金This study was supported by the National Natural Science Fundation of China
文摘As compared with the control,the malondialdehyde(MDA)levels in the cardi-ac,pulmonary,and intestinal tissues were elevated(P【0.05),and the superoxide dismu-tase activities in the cardiac,pulmonary,and intestinal tissues increased(P【0.05)at the30th min after endotoxic shock;the former in the cardiac,hepatic,renal,pulmonary,andintestinal tissues were elevated(P【0.05～0.001)and the latter in the cardiac,pulmona-ry,and intestinal tissues decreased in the 2nd h after shock;and the former were marke-dly elevated(P【0.01～0.001)and the latter severely decreased(P【【0.05～0.001)in allthe visceral tissues tested in the 4th h after shock.These data showed that lipid peroxid-ation mediated through oxygen-derived free radicals brought about tissue damage of theviscera listed above,which occurred earlier in the heart,the lungs and the intestines thanin the liver and the kidneys,and superoxide dismutase(SOD)activity was suppressed inthe late stage of endotoxic shock.
文摘[Objective] To investigate the relationship between perinatal diseases and contents of superoxide dismutase （SOD） and malondialde- hyde （MDA） in serum of dairy cows. [ Method] A total of 38 dairy cows including 22 healthy cows, five cows with ketosis, four cows with fatty liver and seven cows with retained fatal placenta in perinatal period were selected. The contents of SOD and MDA in serum were respectively determined at different times ante partum and post partum. [Result] In the dairy cows with perinatal diseases, the SOD activity is lower and the MDA content was higher than that in the healthy dairy cows during perinatal period. [Conclusion] The antioxidant activity of dairy cows with perinatal diseases is lower than that of healthy dairy cows during perinatal period.
