BACKGROUND Previous studies found several factors associated with suicide in schizophrenic patients,such as age,sex,education level,history of suicide attempts,psychotic symptoms,social factors,and substance abuse.How...BACKGROUND Previous studies found several factors associated with suicide in schizophrenic patients,such as age,sex,education level,history of suicide attempts,psychotic symptoms,social factors,and substance abuse.However,there might be some additional factors that were not considered in previous studies but may be correlated with a greater likelihood of suicide attempts,such as medication and treatment.AIM To investigate the prevalence of suicide attempts and identify the risk of suicidality in hospitalized schizophrenia patients.METHODS This is a cross-sectional study of schizophrenic patients admitted to a psychiatric hospital who were 18 years of age or more.The outcomes and possible suicide risk factors in these patients were collated.The current suicide risk was evaluated using the mini-international neuropsychiatric interview module for suicidality and categorized as none(0 points),mild(1-8 points),moderate(9-16 points),or severe(17 or more points).This study used ordinal logistic regression to assess the association of potential risk factors with the current suicide risk in schizophrenic patients.RESULTS Of 228 hospitalized schizophrenia patients,214(93.9%)were included in this study.The majority(79.0%)of patients were males.Females appeared to have a slightly higher suicidality risk than males,with borderline significance.With regard to the current suicide risk assessed with the mini-international neuropsychiatric interview,172(80.4%)schizophrenic patients scored zero,20(9.4%)had a mild risk,8(3.7%)had a moderate risk,and 14(6.5%)had a severe risk.The total prevalence of current suicide risk in these schizophrenic patients was 19.6%.Based on multivariable ordinal logistic regression analysis with backward elimination,it was found that younger age,a current major depressive episode,receiving fluoxetine or lithium carbonate in the previous month,or a relatively higher Charlson comorbidity index score were all significantly and independently associated with a higher level of suicide risk.CONCLUSION The prev展开更多
目的探讨抑郁障碍青少年反刍思维与抑郁症状和自杀未遂的关系,及反刍思维在抑郁症状和自杀未遂间的中介作用。方法对331例11~18岁抑郁障碍青少年开展问卷调查,采用病人健康问卷(patient health questionnaire-9,PHQ-9)评估抑郁症状、反...目的探讨抑郁障碍青少年反刍思维与抑郁症状和自杀未遂的关系,及反刍思维在抑郁症状和自杀未遂间的中介作用。方法对331例11~18岁抑郁障碍青少年开展问卷调查,采用病人健康问卷(patient health questionnaire-9,PHQ-9)评估抑郁症状、反刍思维量表-10简表(ruminative responses scale,RRS-10)评估反刍思维,采用MINI 5.0中文版自杀模块评估自杀行为。应用SPSS 23.0对数据进行描述统计、χ^(2)检验、t检验、Spearman相关分析和分层回归分析;应用SPSS PROCESS V 3.4插件进行Bootstrap中介效应检验。结果抑郁障碍青少年自杀未遂发生率为53.78%,其中女孩(59.48%)显著高于男孩(40.40%),差异有统计学意义(χ^(2)=10.16,P<0.01)。与无自杀未遂组相比,自杀未遂组在PHQ-9[(11.08±9.26)分与(14.43±7.49)分,t=-3.634,P<0.01]、强迫思考[(10.76±3.89)分与(12.44±3.87)分,t=-3.926,P<0.01]、反省深思[(10.05±3.54)分与(11.20±3.33)分,t=-3.044,P<0.01]和反刍思维总量表[(20.81±6.78)分与(23.64±6.42)分,t=-3.898,P<0.01]均差异有统计学意义。回归分析显示女孩(β=0.175,t=3.228,P=0.001)、抑郁症状(β=0.168,t=3.082,P=0.002)、反刍思维(β=0.138,t=2.364,P=0.019)是自杀未遂的风险因素。反刍思维在抑郁症状与自杀未遂之间起着完全中介效应(效应值=0.013,95%CI=0.003~0.027)。抑郁症状能显著正向预测反刍思维(P<0.01);反刍思维显著正向预测自杀未遂(P<0.05)。结论抑郁障碍青少年自杀未遂发生率较高,其抑郁症状主要通过反刍思维影响自杀未遂,临床中应对反刍思维进行有效的评估和干预,通过心理治疗调整患者认知反应方式,减轻反刍思维,提高心理健康水平,降低自杀发生率。展开更多
Research has indicated that child maltreatment is associated with an increased likelihood of mental disorders and suicidal ideation and attempts that continues into adulthood. The purpose of this paper is to provide a...Research has indicated that child maltreatment is associated with an increased likelihood of mental disorders and suicidal ideation and attempts that continues into adulthood. The purpose of this paper is to provide a synopsis of the recent published research from 2006 to 2010 on the association between child maltreatment and Axis I mental disorders and suicidal ideation and attempts. The databases MEDLINE and PsycINFO were searched for relevant and high quality citations up to October 2010. The results indicated that all types of child maltreatment examined are linked to reduced mental health. A general noted trend in the literature is that earlier age of onset of child maltreatment is associated with poorer mental health outcomes. Sex differences do exist with some disorders being more likely among males (e.g., anti-social behaviour) and other more likely among females (e.g., depression, PTSD, substance use disorders) following child maltreatment.展开更多
基金Supported by the Faculty of Medicine,Chiang Mai University,No.046/2557Chiang Mai University,No.04/2562
文摘BACKGROUND Previous studies found several factors associated with suicide in schizophrenic patients,such as age,sex,education level,history of suicide attempts,psychotic symptoms,social factors,and substance abuse.However,there might be some additional factors that were not considered in previous studies but may be correlated with a greater likelihood of suicide attempts,such as medication and treatment.AIM To investigate the prevalence of suicide attempts and identify the risk of suicidality in hospitalized schizophrenia patients.METHODS This is a cross-sectional study of schizophrenic patients admitted to a psychiatric hospital who were 18 years of age or more.The outcomes and possible suicide risk factors in these patients were collated.The current suicide risk was evaluated using the mini-international neuropsychiatric interview module for suicidality and categorized as none(0 points),mild(1-8 points),moderate(9-16 points),or severe(17 or more points).This study used ordinal logistic regression to assess the association of potential risk factors with the current suicide risk in schizophrenic patients.RESULTS Of 228 hospitalized schizophrenia patients,214(93.9%)were included in this study.The majority(79.0%)of patients were males.Females appeared to have a slightly higher suicidality risk than males,with borderline significance.With regard to the current suicide risk assessed with the mini-international neuropsychiatric interview,172(80.4%)schizophrenic patients scored zero,20(9.4%)had a mild risk,8(3.7%)had a moderate risk,and 14(6.5%)had a severe risk.The total prevalence of current suicide risk in these schizophrenic patients was 19.6%.Based on multivariable ordinal logistic regression analysis with backward elimination,it was found that younger age,a current major depressive episode,receiving fluoxetine or lithium carbonate in the previous month,or a relatively higher Charlson comorbidity index score were all significantly and independently associated with a higher level of suicide risk.CONCLUSION The prev
文摘目的探讨抑郁障碍青少年反刍思维与抑郁症状和自杀未遂的关系,及反刍思维在抑郁症状和自杀未遂间的中介作用。方法对331例11~18岁抑郁障碍青少年开展问卷调查,采用病人健康问卷(patient health questionnaire-9,PHQ-9)评估抑郁症状、反刍思维量表-10简表(ruminative responses scale,RRS-10)评估反刍思维,采用MINI 5.0中文版自杀模块评估自杀行为。应用SPSS 23.0对数据进行描述统计、χ^(2)检验、t检验、Spearman相关分析和分层回归分析;应用SPSS PROCESS V 3.4插件进行Bootstrap中介效应检验。结果抑郁障碍青少年自杀未遂发生率为53.78%,其中女孩(59.48%)显著高于男孩(40.40%),差异有统计学意义(χ^(2)=10.16,P<0.01)。与无自杀未遂组相比,自杀未遂组在PHQ-9[(11.08±9.26)分与(14.43±7.49)分,t=-3.634,P<0.01]、强迫思考[(10.76±3.89)分与(12.44±3.87)分,t=-3.926,P<0.01]、反省深思[(10.05±3.54)分与(11.20±3.33)分,t=-3.044,P<0.01]和反刍思维总量表[(20.81±6.78)分与(23.64±6.42)分,t=-3.898,P<0.01]均差异有统计学意义。回归分析显示女孩(β=0.175,t=3.228,P=0.001)、抑郁症状(β=0.168,t=3.082,P=0.002)、反刍思维(β=0.138,t=2.364,P=0.019)是自杀未遂的风险因素。反刍思维在抑郁症状与自杀未遂之间起着完全中介效应(效应值=0.013,95%CI=0.003~0.027)。抑郁症状能显著正向预测反刍思维(P<0.01);反刍思维显著正向预测自杀未遂(P<0.05)。结论抑郁障碍青少年自杀未遂发生率较高,其抑郁症状主要通过反刍思维影响自杀未遂,临床中应对反刍思维进行有效的评估和干预,通过心理治疗调整患者认知反应方式,减轻反刍思维,提高心理健康水平,降低自杀发生率。
文摘Research has indicated that child maltreatment is associated with an increased likelihood of mental disorders and suicidal ideation and attempts that continues into adulthood. The purpose of this paper is to provide a synopsis of the recent published research from 2006 to 2010 on the association between child maltreatment and Axis I mental disorders and suicidal ideation and attempts. The databases MEDLINE and PsycINFO were searched for relevant and high quality citations up to October 2010. The results indicated that all types of child maltreatment examined are linked to reduced mental health. A general noted trend in the literature is that earlier age of onset of child maltreatment is associated with poorer mental health outcomes. Sex differences do exist with some disorders being more likely among males (e.g., anti-social behaviour) and other more likely among females (e.g., depression, PTSD, substance use disorders) following child maltreatment.
