By suspension cultivating of Lithospermum erythrorhizon and determining the dynamic curves, a structural kinetic model was established. By using the equation sets including 14 parameters and 9 state variables,the chan...By suspension cultivating of Lithospermum erythrorhizon and determining the dynamic curves, a structural kinetic model was established. By using the equation sets including 14 parameters and 9 state variables,the changes of excellular carbon source, intracellular carbon source, intracellular structural components,intracellular intermediate,cell respiration loss and intra/extracellular products were discussed. The model parameters were estimated by the Runge-Kutta method and the nonlinear Powell method. The sensitivity analysis was done. The simulation results could fit the real curves quite well. It was the first time to use a structural model to describe the suspension culture dynamics of Lithospermum erythrorhizon cells. The structural model was also the foundation for further study.展开更多
文摘By suspension cultivating of Lithospermum erythrorhizon and determining the dynamic curves, a structural kinetic model was established. By using the equation sets including 14 parameters and 9 state variables,the changes of excellular carbon source, intracellular carbon source, intracellular structural components,intracellular intermediate,cell respiration loss and intra/extracellular products were discussed. The model parameters were estimated by the Runge-Kutta method and the nonlinear Powell method. The sensitivity analysis was done. The simulation results could fit the real curves quite well. It was the first time to use a structural model to describe the suspension culture dynamics of Lithospermum erythrorhizon cells. The structural model was also the foundation for further study.
