3DMove software, based on the three-dimension structural model of geologic inter- pretation, can forecast reservoir cracks from the point of view of formation of the structural ge- ology, and analyze the characteristi...3DMove software, based on the three-dimension structural model of geologic inter- pretation, can forecast reservoir cracks from the point of view of formation of the structural ge- ology, and analyze the characteristics of the cracks. 3DMove software dominates in forecasting cracks. We forecast the developments and directions of the cracks in Chengbei buried hill with the application of forecasting technique in 3DMove software, and obtain the chart about strain distributing on top in buried hill and the chart about relative density and orientation and the chart about the analysis of crack unsealing. In Chengbei 30 buried hill zone, north-west and north-east and approximately east-west cracks in Cenozoic are very rich and the main directions in every fault block are different. Forecasting results that are also verified by those of drilling approxi- mately accord with the data from well logging, the case of which shows that the technique has the better ability in forecasting cracks, and takes more effects on exploration and exploitation of crack reservoir beds in ancient buried hill reservoirs.展开更多
Spinal cord injury results in paralysis, sensory disturbances, sphincter dysfunction, and multiple systemic secondary conditions, most arising from autonomic dysregulation. All this produces profound negative psychoso...Spinal cord injury results in paralysis, sensory disturbances, sphincter dysfunction, and multiple systemic secondary conditions, most arising from autonomic dysregulation. All this produces profound negative psychosocial implications for affected people, their families, and their communities;the financial costs can be challenging for their families and health institutions. Treatments aimed at restoring the spinal cord after spinal cord injury, which have been tested in animal models or clinical trials, generally seek to counteract one or more of the secondary mechanisms of injury to limit the extent of the initial damage. Most published works on structural/functional restoration in acute and chronic spinal cord injury stages use a single type of treatment: a drug or trophic factor, transplant of a cell type, and implantation of a biomaterial. Despite the significant benefits reported in animal models, when translating these successful therapeutic strategies to humans, the result in clinical trials has been considered of little relevance because the improvement, when present, is usually insufficient. Until now, most studies designed to promote neuroprotection or regeneration at different stages after spinal cord injury have used single treatments. Considering the occurrence of various secondary mechanisms of injury in the acute and sub-acute phases of spinal cord injury, it is reasonable to speculate that more than one therapeutic agent could be required to promote structural and functional restoration of the damaged spinal cord. Treatments that combine several therapeutic agents, targeting different mechanisms of injury, which, when used as a single therapy, have shown some benefits, allow us to assume that they will have synergistic beneficial effects. Thus, this narrative review article aims to summarize current trends in the use of strategies that combine therapeutic agents administered simultaneously or sequentially, seeking structural and functional restoration of the injured spinal cord.展开更多
The pre-Eocene history of the region around the present South China Sea is not well known. New multi-channel seismic profiles provide valuable insights into the probable Mesozoic history of this region. Detailed struc...The pre-Eocene history of the region around the present South China Sea is not well known. New multi-channel seismic profiles provide valuable insights into the probable Mesozoic history of this region. Detailed structural and stratigraphic interpretations of the multi-channel seismic profiles, calibrated with relevant drilling and dredging data, show major Mesozoic structural features. A structural restoration was done to remove the Cenozoic tectonic influence and calculate the Mesozoic tectonic compression ratios. The results indicate that two groups of compressive stress with diametrically opposite orientations, S(S)E– N(N)W and N(N)W–S(S)E, were active during the Mesozoic. The compression ratio values gradually decrease from north to south and from west to east in each stress orientation. The phenomena may be related to the opening of the proto-South China Sea(then located in south of the Nansha block) and the rate at which the Nansha block drifted northward in the late Jurassic to late Cretaceous. The Nansha block drifted northward until it collided and sutured with the southern China margin. The opening of the present South China Sea may be related to this suture zone, which was a tectonic zone of weakness.展开更多
基金supported by the Knowledge Innovation Program of CAS(Grant No.40276022)Fundamental Science Research Program of Ministry of Science&Technology of China(Grant No.200046704).
文摘3DMove software, based on the three-dimension structural model of geologic inter- pretation, can forecast reservoir cracks from the point of view of formation of the structural ge- ology, and analyze the characteristics of the cracks. 3DMove software dominates in forecasting cracks. We forecast the developments and directions of the cracks in Chengbei buried hill with the application of forecasting technique in 3DMove software, and obtain the chart about strain distributing on top in buried hill and the chart about relative density and orientation and the chart about the analysis of crack unsealing. In Chengbei 30 buried hill zone, north-west and north-east and approximately east-west cracks in Cenozoic are very rich and the main directions in every fault block are different. Forecasting results that are also verified by those of drilling approxi- mately accord with the data from well logging, the case of which shows that the technique has the better ability in forecasting cracks, and takes more effects on exploration and exploitation of crack reservoir beds in ancient buried hill reservoirs.
文摘Spinal cord injury results in paralysis, sensory disturbances, sphincter dysfunction, and multiple systemic secondary conditions, most arising from autonomic dysregulation. All this produces profound negative psychosocial implications for affected people, their families, and their communities;the financial costs can be challenging for their families and health institutions. Treatments aimed at restoring the spinal cord after spinal cord injury, which have been tested in animal models or clinical trials, generally seek to counteract one or more of the secondary mechanisms of injury to limit the extent of the initial damage. Most published works on structural/functional restoration in acute and chronic spinal cord injury stages use a single type of treatment: a drug or trophic factor, transplant of a cell type, and implantation of a biomaterial. Despite the significant benefits reported in animal models, when translating these successful therapeutic strategies to humans, the result in clinical trials has been considered of little relevance because the improvement, when present, is usually insufficient. Until now, most studies designed to promote neuroprotection or regeneration at different stages after spinal cord injury have used single treatments. Considering the occurrence of various secondary mechanisms of injury in the acute and sub-acute phases of spinal cord injury, it is reasonable to speculate that more than one therapeutic agent could be required to promote structural and functional restoration of the damaged spinal cord. Treatments that combine several therapeutic agents, targeting different mechanisms of injury, which, when used as a single therapy, have shown some benefits, allow us to assume that they will have synergistic beneficial effects. Thus, this narrative review article aims to summarize current trends in the use of strategies that combine therapeutic agents administered simultaneously or sequentially, seeking structural and functional restoration of the injured spinal cord.
基金supported by the National Natural Science Foundation of China(Nos.41476039,91328205,415760 68 and 41606080)
文摘The pre-Eocene history of the region around the present South China Sea is not well known. New multi-channel seismic profiles provide valuable insights into the probable Mesozoic history of this region. Detailed structural and stratigraphic interpretations of the multi-channel seismic profiles, calibrated with relevant drilling and dredging data, show major Mesozoic structural features. A structural restoration was done to remove the Cenozoic tectonic influence and calculate the Mesozoic tectonic compression ratios. The results indicate that two groups of compressive stress with diametrically opposite orientations, S(S)E– N(N)W and N(N)W–S(S)E, were active during the Mesozoic. The compression ratio values gradually decrease from north to south and from west to east in each stress orientation. The phenomena may be related to the opening of the proto-South China Sea(then located in south of the Nansha block) and the rate at which the Nansha block drifted northward in the late Jurassic to late Cretaceous. The Nansha block drifted northward until it collided and sutured with the southern China margin. The opening of the present South China Sea may be related to this suture zone, which was a tectonic zone of weakness.