加速寿命试验(ALT)是用加大试验应力来缩短试验周期的一种基本寿命试验方法,其目的在于:以较低的试验代价(例如试验样本、试验周期等)获取具有足够精度的寿命信息.在现有方法的基础上,基于试验应力加载顺序的变化将可能使试验效率发生...加速寿命试验(ALT)是用加大试验应力来缩短试验周期的一种基本寿命试验方法,其目的在于:以较低的试验代价(例如试验样本、试验周期等)获取具有足够精度的寿命信息.在现有方法的基础上,基于试验应力加载顺序的变化将可能使试验效率发生重大改善的设想,该文提出了一种新的试验方法——序降应力加速寿命试验,然后根据失效物理的退化模型,与其它几种试验方法比较了其有效性,并且给出了序降应力加速寿命试验在we ibu ll分布场合下的分布函数.展开更多
Four weeks of uncertain stress was used to establish an animal model of chronic stress. Basic fibroblast growth factor was injected daily for 15 days following stress induction. Cell morphology in the hippocampal CA3 ...Four weeks of uncertain stress was used to establish an animal model of chronic stress. Basic fibroblast growth factor was injected daily for 15 days following stress induction. Cell morphology in the hippocampal CA3 region of chronic stress mice revealed cell damage. Nitric oxide content and calcium concentration were significantly increased in the hippocampus, and learning and memory functions were significantly decreased. After basic fibroblast growth factor intervention, Ca2~ overload was decreased and neuronal damage was relieved in hippocampal neurons, which improved learning and memory functions in chronic stress mice. Latency was prolonged and the number of errors was decreased in a passive avoidance test.展开更多
文摘加速寿命试验(ALT)是用加大试验应力来缩短试验周期的一种基本寿命试验方法,其目的在于:以较低的试验代价(例如试验样本、试验周期等)获取具有足够精度的寿命信息.在现有方法的基础上,基于试验应力加载顺序的变化将可能使试验效率发生重大改善的设想,该文提出了一种新的试验方法——序降应力加速寿命试验,然后根据失效物理的退化模型,与其它几种试验方法比较了其有效性,并且给出了序降应力加速寿命试验在we ibu ll分布场合下的分布函数.
基金the "Eleventh Five-Year" Scientific and Technological Research Projects of the Education Department of Jilin Province, No. [2008]137
文摘Four weeks of uncertain stress was used to establish an animal model of chronic stress. Basic fibroblast growth factor was injected daily for 15 days following stress induction. Cell morphology in the hippocampal CA3 region of chronic stress mice revealed cell damage. Nitric oxide content and calcium concentration were significantly increased in the hippocampus, and learning and memory functions were significantly decreased. After basic fibroblast growth factor intervention, Ca2~ overload was decreased and neuronal damage was relieved in hippocampal neurons, which improved learning and memory functions in chronic stress mice. Latency was prolonged and the number of errors was decreased in a passive avoidance test.
