Alginate were hydrophobically modified by coupling of heptylamine onto it.The composition and structure of the product were characterized by IR and 1HNMR.The result of fluorescence analysis showed that S-0 and S-3 for...Alginate were hydrophobically modified by coupling of heptylamine onto it.The composition and structure of the product were characterized by IR and 1HNMR.The result of fluorescence analysis showed that S-0 and S-3 formed self-aggregates in 0.15mol/L aqueous NaCl solution and their critical aggregation concentration were 0.7g/L and 1.1g/L respectively.The new heptylamine-alginate conjugate was used for immobilization of BSA in the presence of calcium chloride.In addition,the encapsulation rate and the release behavior in deionized water and Tris-Hcl buffer solution(pH7.2) were investigated.Comparing to unmodified alginate,the modified sodium alginate has relative higher encapsulation rate and prolonger release behavior.展开更多
文摘Alginate were hydrophobically modified by coupling of heptylamine onto it.The composition and structure of the product were characterized by IR and 1HNMR.The result of fluorescence analysis showed that S-0 and S-3 formed self-aggregates in 0.15mol/L aqueous NaCl solution and their critical aggregation concentration were 0.7g/L and 1.1g/L respectively.The new heptylamine-alginate conjugate was used for immobilization of BSA in the presence of calcium chloride.In addition,the encapsulation rate and the release behavior in deionized water and Tris-Hcl buffer solution(pH7.2) were investigated.Comparing to unmodified alginate,the modified sodium alginate has relative higher encapsulation rate and prolonger release behavior.
